18 min

EMCrit 298 – Calcium in Exsanguinating Patients with Ricky Ditzel and Jeffrey Siegler EMCrit Podcast - Critical Care and Resuscitation

    • Medicine

Something I have been preaching for a decade has finally gotten the attention and research it deserves. On this episode, I get two of the authors from the Lethal Diamond Paper to discuss hypocalcemia in the bleeding patient.

Ricky Ditzel

Prior Special Operations Combat Medic and current Premed Postbacc Student at Columbia trying to go to medical school

Jeffrey Siegler

EM Doc & EMS Physician at Wash U in St. Louis

Read the Lethal Diamond Paper



* Official JTACS Lethal Diamond



Here is a powerpoint from Ricky

The Lethal Triad Should be the Lethal Diamond

Calcium is an independent part of the death spiral, but it is also intertwined with the other three factors as this diagram demonstrates:





Calcium in Clotting

 















from @MikeEMPharmD  data from: Giancarelli A, Birrer K, Alban R, Hobbs B, Liu-DeRyke X. Hypocalcemia in trauma patients receiving massive transfusion. J Surg Res. 2016;202(1):182-187. [PubMed]

What to Do



* Give calcium with your first unit of blood in trauma (and TXA)

* Consider giving 1g for every 2-4 products you administer during large transfusion

* Send and Respond to Icals



Read these Papers



* MilMed

* Citrate in Cirrhotics

* Hypocalcemia during MTP

* mass trans

* Ionised-calcium-levels-in-major-trauma-patients-who-received-blood-in-the-emergency-department

* Howland WS, Schweizer O, Carlon GC, Goldiner PL. The cardiovascular effects of low levels of ionized calcium during massive transfusion. Surg Gynecol Obstet 1977; 145:581.

* Hypocalcemia in trauma patients receiving massive transfusion. J Surg Res. 2016;202(1):182-187.

* Retrospective Study



Related EMCrit Stuff



* Hypocalcemia

* EMCrit 278 – Labors of Trauma – Blunt Edition (Part 1)

* EMCrit Podcast 13 – Trauma Resus II: Massive Transfusion

* Massive Transfusion Protocol (MTP)



Now on to the Podcast...

Something I have been preaching for a decade has finally gotten the attention and research it deserves. On this episode, I get two of the authors from the Lethal Diamond Paper to discuss hypocalcemia in the bleeding patient.

Ricky Ditzel

Prior Special Operations Combat Medic and current Premed Postbacc Student at Columbia trying to go to medical school

Jeffrey Siegler

EM Doc & EMS Physician at Wash U in St. Louis

Read the Lethal Diamond Paper



* Official JTACS Lethal Diamond



Here is a powerpoint from Ricky

The Lethal Triad Should be the Lethal Diamond

Calcium is an independent part of the death spiral, but it is also intertwined with the other three factors as this diagram demonstrates:





Calcium in Clotting

 















from @MikeEMPharmD  data from: Giancarelli A, Birrer K, Alban R, Hobbs B, Liu-DeRyke X. Hypocalcemia in trauma patients receiving massive transfusion. J Surg Res. 2016;202(1):182-187. [PubMed]

What to Do



* Give calcium with your first unit of blood in trauma (and TXA)

* Consider giving 1g for every 2-4 products you administer during large transfusion

* Send and Respond to Icals



Read these Papers



* MilMed

* Citrate in Cirrhotics

* Hypocalcemia during MTP

* mass trans

* Ionised-calcium-levels-in-major-trauma-patients-who-received-blood-in-the-emergency-department

* Howland WS, Schweizer O, Carlon GC, Goldiner PL. The cardiovascular effects of low levels of ionized calcium during massive transfusion. Surg Gynecol Obstet 1977; 145:581.

* Hypocalcemia in trauma patients receiving massive transfusion. J Surg Res. 2016;202(1):182-187.

* Retrospective Study



Related EMCrit Stuff



* Hypocalcemia

* EMCrit 278 – Labors of Trauma – Blunt Edition (Part 1)

* EMCrit Podcast 13 – Trauma Resus II: Massive Transfusion

* Massive Transfusion Protocol (MTP)



Now on to the Podcast...

18 min