42 min

Episode 15 Convalescent Plasma Breaking Bad Science

    • Science

Recently, the US released an Emergency Use Authorization (EUA) for the use of convalescent plasma in the treatment of COVID-19. What is an EUA? What does it mean? Is it something the population should be concerned about? Does this mean we should be using it on all patients who are attempting to recover from the virus? Join hosts Shanti and Danny as we discuss the importance of this treatment, whether it holds promise and try to make sense of the political landscape surrounding this treatment.


References
Luke, T., et. al.; Meta-analysis: Convalescent Blood Products for Spanish Influenza Pneumonia: A Future H5N1 Treatment?. Annals of Internal Medicine. 17-Oct-2006. 145:8 (599-609). Doi: https://doi.org/10.7326/0003-4819-145-8-200610170-00139 
Chippaux, J., et. al.; Production and Use of Snake Antivenin. Handbook of Natural Toxins (Volume 5 Reptile Venoms and Toxins). 03-Mar-1992. 5 (529 - 555). https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.598.1709&rep=rep1&type=pdf
Nellis, R.; Mayo Finds Convalescent Plasma Safe for Diverse Patients With COVID-19. Mayo Clinic. 18-Jun-2020. https://newsnetwork.mayoclinic.org/discussion/mayo-finds-convalescent-plasma-safe-for-diverse-patients-with-covid-19/
VanArsdel, P.; Allergic Reactions to Penicillin. Journal of the American Medical Association. 18-Jan-1965. 191:3 (238 - 239). Doi: https://10.0.3.233/jama.1965.03080030082012
Perrone, G., et. al.;  Penicillium Species and Their Associated Mycotoxins. Mycotoxigenic Fungi. 07-Dec-2016. (107 - 119) Doi: https://doi.org/10.1007/978-1-4939-6707-0_5
Mayo Clinic. Convalescent Plasma Therapy. Patient Care and Health information: Tests and Procedures. https://www.mayoclinic.org/tests-procedures/convalescent-plasma-therapy/about/pac-20486440
Siripanthong, B., et. al.; Recognizing COVID-19-Related Myocarditis: The Possible Pathophysiology and Proposed Guideline for Diagnosis and Management. Heart Rhythm Society Cardiac Electrophysiology Society. Sep-2020. 17:9 (1463 - 1471). Doi: https://10.0.3.248/j.hrthm.2020.05.001
Ruuskanen, O., et. al.; Viral Pneumonia. The Lancet. 15-Apr-2011. 377:9773 (1264 - 1275). Doi: https://doi.org/10.1016/S0140-6736(10)61459-6



Support the show

Recently, the US released an Emergency Use Authorization (EUA) for the use of convalescent plasma in the treatment of COVID-19. What is an EUA? What does it mean? Is it something the population should be concerned about? Does this mean we should be using it on all patients who are attempting to recover from the virus? Join hosts Shanti and Danny as we discuss the importance of this treatment, whether it holds promise and try to make sense of the political landscape surrounding this treatment.


References
Luke, T., et. al.; Meta-analysis: Convalescent Blood Products for Spanish Influenza Pneumonia: A Future H5N1 Treatment?. Annals of Internal Medicine. 17-Oct-2006. 145:8 (599-609). Doi: https://doi.org/10.7326/0003-4819-145-8-200610170-00139 
Chippaux, J., et. al.; Production and Use of Snake Antivenin. Handbook of Natural Toxins (Volume 5 Reptile Venoms and Toxins). 03-Mar-1992. 5 (529 - 555). https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.598.1709&rep=rep1&type=pdf
Nellis, R.; Mayo Finds Convalescent Plasma Safe for Diverse Patients With COVID-19. Mayo Clinic. 18-Jun-2020. https://newsnetwork.mayoclinic.org/discussion/mayo-finds-convalescent-plasma-safe-for-diverse-patients-with-covid-19/
VanArsdel, P.; Allergic Reactions to Penicillin. Journal of the American Medical Association. 18-Jan-1965. 191:3 (238 - 239). Doi: https://10.0.3.233/jama.1965.03080030082012
Perrone, G., et. al.;  Penicillium Species and Their Associated Mycotoxins. Mycotoxigenic Fungi. 07-Dec-2016. (107 - 119) Doi: https://doi.org/10.1007/978-1-4939-6707-0_5
Mayo Clinic. Convalescent Plasma Therapy. Patient Care and Health information: Tests and Procedures. https://www.mayoclinic.org/tests-procedures/convalescent-plasma-therapy/about/pac-20486440
Siripanthong, B., et. al.; Recognizing COVID-19-Related Myocarditis: The Possible Pathophysiology and Proposed Guideline for Diagnosis and Management. Heart Rhythm Society Cardiac Electrophysiology Society. Sep-2020. 17:9 (1463 - 1471). Doi: https://10.0.3.248/j.hrthm.2020.05.001
Ruuskanen, O., et. al.; Viral Pneumonia. The Lancet. 15-Apr-2011. 377:9773 (1264 - 1275). Doi: https://doi.org/10.1016/S0140-6736(10)61459-6



Support the show

42 min

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