Episode 4: Conformational Ensembles & Teaching Vibe Coding

- News round-up

- Conformational Ensembles Conference

- Preprints discussed:

Multiscale guidance of AlphaFold3 with heterogeneous cryo-EM data (https://www.arxiv.org/abs/2506.04490)

Boltz-2 Towards Accurate and EfficientBinding Affinity Prediction (https://jeremywohlwend.com/assets/boltz2.pdf)

- Guiding vibe coding for science

-Dipsea & Montpelier Mile