Dog Cancer Answers Dog Podcast Network

Inspired by a question from listener Mariana Diaz regarding her Pomeranian, Joya, who is battling lymphoma, this episode explores the potential of T-cell infusions as a follow-up treatment to the CHOP chemotherapy protocol.
Join us as we consult with veterinary oncologist Dr. Megan Duffy to uncover the science, the practicality, and the future of T-cell infusions in canine cancer treatment.
Join our Facebook support group at https://www.dogcancer.com/support
Your Voice Matters!
If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question.
Related Videos:           
Learn about dog lymphoma from Dr. Demian Dressler: https://www.youtube.com/watch?v=PNbQ4mNx938
Did you know dogs can get bone marrow transplant for lymphoma? https://www.youtube.com/watch?v=49DaJWBuOMM
More from Dr. Megan Duffy about new treatments in this in-depth look at Laverdia for dogs with lymphoma: https://www.youtube.com/watch?v=3Didq5brhso
Related Links:
An amazing overview article about Lymphoma in Dogs on DogCancer.com: https://www.dogcancer.com/articles/types-of-dog-cancer/lymphoma-in-dogs/
Chapters:
00:00 - Introduction to T-Cell Infusions for dogs with lymphoma
01:00 - Share Your Story and Ask Your Question
02:00 – Preview T-Cell Infusion Validity and the Practical Challenges of T-Cell Infusions
05:00 - Mariana's Question on T-Cell Infusion for Joya the Pomeranian Fighting Lymphoma with the CHOP Protocol
06:00 – T-Cell Infusion for B-Cell Lymphoma vs. T-Cell Lymphoma with Veterinary Oncologist Dr. Megan Duffy
07:00 - Concerns and Recommendations When Considering T-Cell Infusion Therapy
08:00 – The Experimental Nature and Research on T-Cell Harvesting
09:00 - Blood Volume Needed and T-Cell Infusion Process Explained
10:00 - Future of T-Cell Infusion in Veterinary Medicine
11:00 - Closing Remarks and Reminder to Share Your Own Story!
12:00 - Outro and Disclaimer
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Get to know Dr. Megan Duffy: https://www.dogcancer.com/people/megan-duffy-dvm-acvim-oncology/
For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/
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ELIAS Animal Health CEO Tammie Wahaus returns to Dog Cancer Answers to talk about the company’s immunotherapy for dogs with osteosarcoma, which recently cleared an important milestone on the way to market.
ELIAS hopes their treatment will be accepted and used as a safe and appropriate alternative to chemotherapy in dogs with osteosarcoma. Instead of using chemotherapy to control metastasis, ELIAS uses the dog’s tumor to create a series of vaccines. Once the dog has the vaccinations, their immune system cells are harvested, taken back to the ELIAS labs, and spun up into an “army of angry killer T-cells” that are ready to murder that specific tumor!
It's truly personalized medicine, and it’s the first of its kind in animals OR people. Join us as we follow ELIAS progress on the way to market.
Listen to the first interview here: https://www.youtube.com/watch?v=YGIvyktfXlY
ELIAS Animal Health’s website: https://eliasanimalhealth.com/
Join our Facebook support group at https://dogcancer.com/support
Call +1 808-868-3200 to leave a question on our Listener Line for a future show!
Related Videos:           
Tammie Wahaus’s first interview: https://www.youtube.com/watch?v=YGIvyktfXlY
Dr. Susan Ettinger, AKA Dr. Sue Cancer Vet, on HER2/NEU immunotherapy: https://www.youtube.com/watch?v=AEbcZVLoNeY
Chapters:
00:00 - Introduction: ELIAS Animal Health's Alternative to Chemotherapy for Dog Osteosarcoma
02:05 – Personalized Cancer Treatment for Dogs on the Horizon?
04:06 - Regulatory Landscape: Navigating the USDA Process
05:43 - Clinical Trial Results: Promising Alternatives to Traditional Chemotherapy
08:30 - Comparison with Chemotherapy: Effectiveness and Safety Insights
10:56 - Future Look: Will Carboplatin Continue to Be Standard of Care for Osteosarcoma?
12:45 - Safety Concerns: Cytokine Release Syndrome from Immunotherapy
19:30 – New Targets: Combining Immunotherapies, Adding Chemotherapy
20:02 – Metastatic Osteosarcoma: Adding a Checkpoint Inhibitor
22:08 – Experimental Use: Veterinarian Experience with Using ELIAS Under the Experimental License
26:15 – Human Vs. Animal Regulatory Approvals: What the FDA and USDA Do
28:41 - Human Application: Potential Implications for One Health Initiatives
33:40 - What Happens Next: Label to USDA Licensed Product and Commercial Launch
34:28 - Conclusion: Looking Forward to a Brighter Future in Canine Oncology
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Get to know Tammie Wahaus: https://www.dogcancer.com/people/tammie-wahaus/
For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/
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Is Palladia safe? Does it have a lot of side effects? Does giving my dog a cancer drug at home multiple times a week make my dog “toxic”? Can my dog with other health problems take this drug safely?
Palladia was approved for dogs with high-grade mast cell tumors in dogs over a decade ago. But since then, veterinary oncologists have started using it in many solid tumor types. They’ve also tweaked the doses to lessen the risk of side effects.
Veterinary oncologist Dr. Megan Duffy joins us for an in-depth look at this “kind of weird, exciting drug.” She explains a little about how it works, when it is used, and answers ALL the questions that came up in our Facebook Dog Cancer Support Group about this drug.
If your veterinarian wants to start your dog on Palladia, and you’re wondering why … this is a must-watch video for you because Dr. Duffy has advice about how to know if Palladia might help YOUR dog’s case.
Join our Facebook support group at https://dogcancer.com/support
Call +1 808-868-3200 to leave a question on our Listener Line for a future show!
Related Videos:           
Our first show on Palladia many years ago: https://www.youtube.com/watch?v=ShOzhnd-Hw4
Chemotherapy for Dogs Demystified: https://www.youtube.com/watch?v=V6_fWtQbxfw
A wonderful show about how Regular Veterinarians Can Offer Chemotherapy: https://www.youtube.com/watch?v=1izf0aw-cr4
Related Links:
Our DogCancer.com article on Palladia: https://www.dogcancer.com/articles/drugs/palladia-for-dogs/
Our DogCancer.com article about whether chemotherapy for dogs is worth doing: https://www.dogcancer.com/articles/drugs/dog-chemotherapy/
Dr. Duffy mentioned using Palladia at the same time as metronomic chemotherapy. Here’s our DogCancer.com article about that: https://www.dogcancer.com/articles/diagnosis-and-medical-procedures/metronomic-chemotherapy-for-dogs/
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Get to know Megan Duffy, DVM, ACVIM (Oncology): https://www.dogcancer.com/people/megan-duffy-dvm-acvim-oncology/ 
For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/
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When Sheila Cooperman’s husband said he wanted a dog, she said that was fine and good, but it would be HIS responsibility. Then she met Tucker, the Boykin Spaniel, and transformed into a full-fledged Dog Mom.
When Tucker died suddenly of lymphoma last year, Sheila, a teacher with decades of experience and a literacy expert, turned to writing to help herself cope. Her “Friday posts” on social media are turning into books.
Sheila’s message that “writing is for everyone; you don’t have to be a writer” is a refreshing one and much-needed for those who are going through a tough time. In fact, Sheila has realized recently that her grieving for Tucker has helped her to resolve her grief over losing her own mother to the same disease fifty years ago.
This is truly a very special episode of Dog Cancer Answers!
Join our Facebook support group at https://dogcancer.com/support
Call +1 808-868-3200 to leave a question on our Listener Line for a future show!
Related Videos:           
Dr. Dressler’s biggest signs that a dog is nearing the end of their life: https://www.youtube.com/watch?v=Ff4zmrzS0Mk
Wendy Van de Poll on how to cope and prepare for your dog’s death:
https://www.youtube.com/watch?v=J5Bh1wIp5bY
Related Links:
A Tucker story reprinted with permission from Dr. Sheila Cooperman on DogCancer.com: https://www.dogcancer.com/perspectives/hospice-and-end-of-life/tucker-week-22/
Just one of the beautiful Tucker posts in our support group: https://www.facebook.com/groups/dogcancersupport/permalink/3538454839753356/
Everything-Lymphoma article on DogCancer.com: https://www.dogcancer.com/articles/types-of-dog-cancer/lymphoma-in-dogs/
A helpful perspective on how to know your dog is near the end of their life: https://www.dogcancer.com/perspectives/hospice-and-end-of-life/warning-signs-dog-is-dying/
The Dog Cancer Survival Guide: Full Spectrum Treatments to Optimize Your Dog’s Life Quality & Longevity by Dr. Demian Dressler and Dr. Susan Ettinger, DVM, Dip. ACVIM (Oncology) is available everywhere books are sold and on https://dogcancerbook.com
Chapters:
00:00 START
01:20 About Tucker
03:57 Discovering Tucker’s Mutated B-Cell Lymphoma
07:07 Tucker's True Tail Cancer Journey
14:41 Finding the Facebook Support Group
17:25 Finding Writing After Tucker's Passing
22:25 Writing a Book
25:44 Writing as Catharsis for Everyone, Not Just “Writers”
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Get to know Sheila Cooperman, PhD: https://www.dogcancer.com/people/sheila-cooperman-phd/
For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/
Learn more about your ad choices. Visit megaphone.fm/adchoices

If you’re trying to decide between dog euthanasia or a natural death, Molly Jacobson, editor-in-chief at DogCancer.com, has a dog cancer tip for you. Turning your thoughts around and understanding what death really is can help you help your dog at this most tender time. 
Join our Facebook support group at https://facebook.com/groups/dogcancersupport
Call +1 808-868-3200 to leave a question on our Listener Line for a future show!
Related Videos:           
Podcast episode with more dog cancer tips on how to handle change: https://www.youtube.com/watch?v=lHWVGRjUjjc
An Interview with Lap of Love founder Dani McVety: https://www.youtube.com/watch?v=Y28IQXhAtXk
Related Links:
Article on DogCancer.com about euthanasia: https://www.dogcancer.com/articles/hospice-and-end-of-life/dog-euthanasia/
Chapters:
00:00 Start
00:59 About Molly
01:31 Euthanasia Is Not Giving Up
02:04 Dying Happens in Stages
04:16 Natural Death Does Not Always Equal an Easy Death
06:23 Sparing Suffering
07:15 Impossible to “Choose” the Moment of Death
08:49 Reframing Euthanasia vs. Natural Death
10:44 Outro
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Get to know Molly Jacobson: https://www.dogcancer.com/people/molly-jacobson/
For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/
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A company in Raleigh, North Carolina, is using worms to sniff dog urine for cancer metabolites. It’s a simple, non-invasive, relatively inexpensive way to screen for cancer. Could this test catch cancer early enough to make a dent in the number of dogs who succumb to their #1 killer?
Six to ten million dogs are diagnosed with cancer every year in the U.S. alone, and veterinarians think half of those cases could be treated and cured if caught early. But our canine companions are naturally stoic, so we don’t often get it early enough. If early detection methods were available and less expensive, it would help us catch cancer earlier. And that might save millions of dogs every year from their deadliest illness.
Imaging tests like ultrasound, x-ray, and MRI are expensive and invasive. Few dog lovers can afford to engage them routinely once a dog hits their senior years at age seven.
Oncotect’s promise is that their urine test, which costs much less and involves a simple urine catch, will help find dog cancer early. Once they receive the urine in their lab, the company uses C. elegans nematodes, tiny little worms, to “sniff” the urine. Their behavior helps discern whether cancer by-products are present in the urine sample.
We are joined today by Oncotect CEO and founder, Chan Namgong. Also, Dr. Page Wages, a Raleigh-area veterinarian who has been using Oncotect for years with hundreds of patients and says this urine test has changed the way she screens for cancer.
Join our Facebook support group at https://facebook.com/groups/dogcancersupport
Call +1 808-868-3200 to leave a question on our Listener Line for a future show!
Related Videos:           
Early signs of cancer you should pay attention to from veterinary oncologist Dr. David Vail: https://www.youtube.com/watch?v=bBuIqGadKbQ
A blood test for dog cancer, OncoK9 with Dr. Andi Flory: https://www.youtube.com/watch?v=7ahExyrbs8U
Someday poop might be used as a screening tool and/or diagnostic for dog cancer, too! https://www.youtube.com/watch?v=ZDkV5oKS0vw
Related Links:
Oncotect website: https://oncotect.co/
Chapters:
00:00 START
00:03 Introduction
01:21 What are C. Elegans
02:40 Using C. Elegans To Detect Cancer?
04:55 Conversation with Dr. Page Wages
09:29 False Positives Using Oncotect?
14:18 The Most Bizarre Dog Cancer Oncotect Found
15:02 How Often Dr. Wages Uses Oncotect
21:23 Conversation with Chan Namgong, CEO and Founder of Oncotect
21:44 How Worms Can Be Used to Detect Dog Cancer
24:11 Oncotect Reliability
26:01 Degree of Effectiveness
28:12 All About Nematodes
31:44 What’s on the Report
34:41 How Much Oncotect Costs
43:48 How To Get Oncotect
48:00 What Other Veterinarians Have Told Us
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Get to know Dr. Page Wages: https://www.dogcancer.com/people/page-wages-dvm/
Get to know Oncotect CEO and founder Chan Namgong: https://www.dogcancer.com/people/chan-namgong/
For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/
Learn more about your ad choices. Visit megaphone.fm/adchoices