Gynecological manifestations of GVHD

Graft-versus-host disease (GVHD) presenting in the vulva and vagina can often be overlooked. What can be done to detect signs and symptoms, and how is GVHD differentiated from other possible post-transplant complications?

Our host, Dr. Dennis Kim, covers these topics and more with Dr. Michelle Jacobson, a gynecologist and menopause specialist with the Society of Obstetricians and Gynecologists of Canada. Dr. Jacobson also sits on the board of the Canadian Menopause Society and the Menopause Foundation of Canada.

In this episode, the incidence of GVHD in the vulva and vagina is discussed, followed by screening tips and recommendations for specialist referral. Dr. Jacobson also describes the gynecological sequelae associated with stem cell transplant, the similarities between GVHD and other vulvar and vaginal conditions, and provides management options, as well as advice, for talking to patients about their genital health and sexual function.

Don’t miss the conversation!

The views and opinions expressed in this episode are those of the speakers and do not necessarily reflect the views or positions of any entities they represent.

Declaration of conflict of interest:

Dr. Dennis Kim:

• Direct financial relationship including receipt of honoraria: Novartis, Sanofi, Pfizer, Jazz, Paladin. Membership on advisory board: Novartis, Sanofi, Jazz, Paladin. Funded grants, research, or clinical trials: Novartis, Sanofi, Jazz, Paladin.

Dr. Michelle Jacobson:

• Direct financial relationship including receipt of honoraria: AbbVie, Astellas, Bayer, BioSyent, Duchesnay, Hologic, Knight, Lupin, Organon, Pfizer, Searchlight. Membership on advisory board: AbbVie, Astellas, Bayer, BioSyent, Duchesnay, Eisai, Knight, Lupin, Pfizer. Funded grants, research, or clinical trials: Health Canada, Canadian Institutes of Health Research

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