Learning & Living STEMM in Connecticut

How Ketamine is Rewriting the Biology of Depression

What if the traditional view of depression—a simple imbalance of serotonin—was wrong? In this episode of Learning and Living STEM in Connecticut, host Tanimu Deleon talks with Dr. John Krystal, Chair of Psychiatry at Yale and recipient of the 2026 Connecticut Medal of Technology, to discuss his groundbreaking discovery of ketamine's rapid antidepressant effects and how it changed our understanding of depression's biology.