How to Live Forever with Dr. Aubrey de Grey

This episode will take you through Dr. Aubrey de Grey’s Seven Pillars of aging, the research that he's currently doing, his opinion on biological age, AGEs and the different sources, and the impact of growth hormone on biological age.

Who is Dr. Aubrey de Grey?

Aubrey de Grey is an English author and biomedical gerontologist. He is the Chief Science Officer of the SENS Research Foundation and VP of New Technology Discovery at AgeX Therapeutics, Inc.

He is the editor-in-chief of the academic journal Rejuvenation Research, author of The Mitochondrial Free Radical Theory of Aging and co-author of Ending Aging. He is known for his view that medical technology may enable human beings alive today not to die from age-related causes.

He is also an amateur mathematician who has contributed to the study of the Hadwiger–Nelson problem.

His research focuses on whether regenerative medicine can prevent the aging process. He works on the development of what he calls "Strategies for Engineered Negligible Senescence" (SENS), a collection of proposed techniques to rejuvenate the human body and stop aging. 

To this end, he has identified seven types of molecular and cellular damage caused by essential metabolic processes. SENS is a proposed panel of therapies designed to repair this damage. De Grey is an international adjunct professor of the Moscow Institute of Physics and Technology, a fellow of the Gerontological Society of America, the American Aging Association, and the Institute for Ethics and Emerging Technologies.

He has been interviewed in recent years in a number of news sources, including CBS 60 Minutes, the BBC, The New York Times, Fortune Magazine, The Washington Post, TED, Popular Science, The Colbert Report, Time, the Skeptics' Guide to the Universe, and The Joe Rogan Experience. 

He is also a member of Flooved advisory board.

Highlights

[1:57] Where are we in the battle against aging?

[4:29] Dr. de Grey explains the seven aspects of aging

[8:38] Effects of lifestyle on the AGEs and aging

[12:23] Measures for biological age

[18:07] Why haven’t we evolved past aging?

[20:28] Alzheimers, cancer and cardiovascular disease as components of aging

[24:44] Transitioning from computer science to gerontology

[27:53] Dr. de Grey answers the Superhuman six

Resources

The Health Optimisation Summit

Horvath’s Epigenetic clock

Reversing Biological Age by Greg Fahy

Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime

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