A podcast about the body's defenders against disease.
I fell in love with worms with Keke Fairfax
Keke Fairfax joins Immune to discuss the work from her laboratory on understanding how maternal schistosomiasis impairs IL-4 production and B cell expansion in offspring, and modulation of macrophage immunometabolism by helminths.
Environmental enteric dysfunction with Timothy Hand
Tim Hand joins Immune to discuss the work from his laboratory showing that environmental enteric dysfunction, a disease caused by chronic malnutrition and infection, and which is associated with reduced growth and oral vaccine failure, is controlled by an increase in intestinal regulatory T cells.
Trapping viruses in NETs
The immune professors discuss neutrophil extracellular traps, and how IgA-virus immune complexes potentiate this process through Fc receptors on neutrophils.
Bats don't STING like a bee
Immune explore the observation that bat cells display dampened STING-dependent interferon activation, suggesting why bats might have a unique capacity to harbor many viruses.
On this episode of Immune, we answer listener questions about CAR-Macs, complement and COVID-19, sleep and the immune system, caving and the immune system, germinal centers, COVID-19 vaccines and much more.
Got IgA on the brain
On this episode of Immune, IgA-producing plasma cells mobilized from the gut play an unexpected role in suppressing neuroinflammation.
Hello Immune Generals
I am thrilled to have found your podcast. This is exactly what a basic immunology master turned a full time wife and mom in chief needs in her life. Thank you, thank you!
No episode on Li-Meng Yan
Also, that the platypus would be considered a potential vector for COVID *evolution* is pathetic. Transmission? MAYBE. But it is an endangered species! Do you understand the Wright/Fischer maths on population genetics? There are no such things as “infinite pangolins” ...
it’s as if the institutions of science are terminally politicized or have such overinflated egos as to be exhibiting some kind of institutional meningitis. Absolutely pathetic. Between these 3 things — 1️⃣ lack of *real discussion* on Li-Meng Yan 2️⃣ pangolins as inpossibly endangered vectors and 3️⃣ lack of coverage on the importance of “micro-zinc” or bioavailable zinc — modern science and esp. health research has lost all credibility. I have looked at Yan’s research and it is unbelievable how her work has been smeared. There are serious problems in “peer review” and related processes that science can just defame her and trash her research in mainstream media. PATHETIC
Excellent on many levels
The hosts and guests give thorough explanations of the topics at hand. They describe and explain things with an emphasis on the fundamentals. Then they delve into the more technical aspects. Their approach appeals to those new to the topic as well as experts and anyone in between.