18 episodes

Why do some of us age gracefully and others don’t? How do our bodies and minds experience aging at the cellular and molecular level? Why do we even age to begin with? And maybe most importantly, can we do anything about it? Join host Gordon Lithgow at the Buck Institute in California as he speaks with some of the brightest scientific stars on the planet to search for – and actually find answers to – these questions and many more.

We're not getting any younger... yet‪.‬ The Buck Institute

    • Science
    • 5.0 • 43 Ratings

Why do some of us age gracefully and others don’t? How do our bodies and minds experience aging at the cellular and molecular level? Why do we even age to begin with? And maybe most importantly, can we do anything about it? Join host Gordon Lithgow at the Buck Institute in California as he speaks with some of the brightest scientific stars on the planet to search for – and actually find answers to – these questions and many more.

    Season Two Coming Soon!

    Season Two Coming Soon!

    We're back! In season one, we investigated the biology of aging in many different organisms to learn why and how we age. This season we'll take a close look at potential interventions that modify mechanisms of aging biology and may dramatically change the way we age in our lifetimes.

    Get ready for season two of the Buck's podcast We're not getting any younger... yet. with scientist Gordon Lithgow. Subscribe today!
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    • 1 min
    Between the lines: Mobilizing the immune system

    Between the lines: Mobilizing the immune system

    Gordon and Stella revisit key concepts from the conversation with Arne Akbar, such as using sestrins to modulate T-cells and telomeres. Looking back over the course of season one, Stella and Gordon discuss the need to think about aging as an organizing principle, and how to deal with all the things we don't yet know.

    Stay tuned for season two!
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    • 12 min
    Arne Akbar: Immunity and Beyond

    Arne Akbar: Immunity and Beyond

    What role does the immune system play in aging? How do senescent cells evade it and promote inflammation? And what does it reveal about developing effective interventions? Immunologist Arne Akbar joins Gordon to break down the array of actors and pathways involved, including sestrins, immune memory, the gut microbiome, and more. Along the way, Arne highlights the need to connect across research areas, and shares why courage is the most important quality for a scientist to cultivate.
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    • 33 min
    Between the lines: The many fates of cells

    Between the lines: The many fates of cells

    After the conversation with Monica Driscoll, Gordon and show editor Stella connect to discuss the link between cell death and aging, what we can learn from sending worms to space, and the need for personalized medicine in aging interventions. Finally, they look forward to the next episode with immunologist Arne Akbar.
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    • 10 min
    Monica Driscoll: Exploring the Wild World Within

    Monica Driscoll: Exploring the Wild World Within

    How do different cells in our bodies age differently? What exactly happens when a neuron takes out its trash? In this episode, neuroscientist Monica Driscoll takes Gordon on a tour through her serendipitous career. Topics include sloppy developmental biology, enigmatic exophers, worms in space, and the importance of studying things no one else is thinking about.
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    • 38 min
    Between the lines: Genetics and geroprotectors

    Between the lines: Genetics and geroprotectors

    After a wide-ranging conversation with Nir Barzilai, Gordon and show editor Stella discuss efforts to turn research on geroprotective mechanisms into effective interventions, and look forward to the next episode with neuroscientist Monica Driscoll.
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    • 4 min

Customer Reviews

5.0 out of 5
43 Ratings

43 Ratings

Fat Chat kat ,

Fascinating content!

Not the same old trending topic! Covered many aspects of longevity and hope for attainable avenues of health span and lifespan.
Thank you!!!

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