66 episodes

The talks from the researchers in the field of infectious diseases. The podcast is hosted by South Texas Center for Emerging Infectious Diseases (STCEID).

microTalk Karl Klose

    • Life Sciences
    • 4.9, 16 Ratings

The talks from the researchers in the field of infectious diseases. The podcast is hosted by South Texas Center for Emerging Infectious Diseases (STCEID).

    066: The Eyes Have It: Corneal Infections with Eric Pearlman

    066: The Eyes Have It: Corneal Infections with Eric Pearlman

    Our eyes are one of the most sensitive areas on our bodies, and they are constantly bathed in microbes, and yet we rarely get eye infections. However, certain microbes can take advantage of minor injuries to the eye and cause very serious infections that can lead to blindness.

    Dr. Eric Pearlman is a Professor of Ophthalmology at the University of California Irvine and the Director of the Institute for Immunology.

    Dr. Pearlman studies how the immune system is able to fight against bacteria and fungi that manage to infect the cornea.
    Dr. Pearlman talks about how the eye is a specialized site that is resistant to microbial infections, what types of microbes can infect the eye, how neutrophils help protect the eye, how fungi can cause more serious eye infections due to lack of effective antifungals, why damage to the cornea results in so much pain, why everyone chopping wood should wear eye protection, and how his fascination with parasites led to him studying river blindness.
    The microCase for listeners to solve is about Ally Louia, whose mid-life crisis leads to an exotic vacation and a potentially deadly disease.
    Participants:
    Karl Klose, Ph.D. (UTSA)
    Eric Pearlman, Ph.D. (University of California Irvine)
    Janakiram Seshu, Ph.D. (UTSA)
    Mylea Echazarreta (UTSA)

    • 1 hr 5 min
    065: Cheese Please! The Cheese Microbiome with Rachel Dutton

    065: Cheese Please! The Cheese Microbiome with Rachel Dutton

    Cheese is delicious, and also the product of a complex mixture of microbes.

    Different communities of microbes produce the wide variety of cheeses made around the world. Dr. Rachel Dutton is an Assistant Professor at the University of California San Diego who studies cheese microbiomes.

    Dr. Dutton talks about how cheese is made, how the cheese microbiome is a great model for understanding how microbes interact with each other, how the microbial community determines what type of cheese is made, how her experience working on a cheese farm influenced her research, how the long history of cheesemaking practices gives great insight into microbial interactions, where the holes in Swiss cheese come from, and how studying the cheese microbiome has the added benefit of being able to eat your experiments.

    microTalk was pleased to be joined by Dr. Jimmy Ballard (University of Oklahoma Health Science Center) when this podcast was recorded at the ASM Microbe 2019 conference in San Francisco, CA.

    The microCase for listeners to solve is about Houser Sampson, whose voracious appetite for sushi causes him to come down with a mysterious illness.

    Participants:
    Karl Klose, Ph.D. (UTSA)
    Rachel Dutton, Ph.D. (University of California San Diego)
    Janakiram Seshu, Ph.D. (UTSA)
    Mylea Echazarreta (UTSA)
    Jimmy Ballard (OUHSC)

    • 54 min
    064: Fun(gus) in the Sun(gus): Fungal Infections with Neil Clancy

    064: Fun(gus) in the Sun(gus): Fungal Infections with Neil Clancy

    Candida albicans is the most common cause of fungal disease in the United States. C. albicans can cause serious and often fatal systemic infections, especially in hospitalized patients with underlying conditions.
    Dr. Cornelius Clancy is an Associate Professor at the University of Pittsburgh and the Director of the XDR Pathogen Lab. Dr. Clancy talks about the clinical implications of fungal infections, how a physician should communicate with patients, how the unique perspective of a clinician enhances research, why there is a lack of effective antifungal drugs, why the societal cost needs to be factored into the cost of antimicrobials, why there has never been a better time to do science, and what the right motivation is to choose medicine as a career.

    The microCase for listeners to solve is about Alf Viddersane, who gets sick along with all his family and friends at his 50th birthday party.
    Participants:
    Karl Klose, Ph.D. (UTSA)
    Cornelius Clancy, M.D. (University of Pittsburgh)
    Janakiram Seshu, Ph.D. (UTSA)
    Mylea Echazarreta (UTSA)

    • 51 min
    063: Tick Schtick: Lyme Disease with Tim Sellati

    063: Tick Schtick: Lyme Disease with Tim Sellati

    Lyme Disease is the most common vector-borne disease in the United States.  The bacterium Borrelia burgdorferi is transmitted to humans through the bite of a deer tick, and can lead to the debilitating disease that most commonly is associated with arthritis, but can also cause heart and neurological problems.
    Dr. Tim Sellati is the Chief Scientific Officer at the Global Lyme Alliance (GLA).  GLA is dedicated to development of more effective diagnostics and treatments of Lyme and other tick-borne diseases. 
    Dr. Sellati talks about how people can avoid Lyme Disease, what typically happens when someone is infected with Borrelia burdorferi, how the immune response against the bacteria is the cause of disease symptoms, why people in the Northeast U.S. are more likely to get Lyme Disease, whether tick eradication is a possibility for the elimination of Lyme, how the internet can spread misinformation that inhibits the control of this disease, and what the likely prospects are for a Lyme Disease vaccine. 
    The microCase for listeners to solve is about Wandering River Spirit, a young hippie who comes down with a potentially debilitating disease while trying to volunteer with a global health charity.
    Participants: Karl Klose, Ph.D. (UTSA) Timothy Sellati, Ph.D. (Global Lyme Alliance) Janakiram Seshu, Ph.D. (UTSA) Mylea Echazarreta (UTSA) Subscribe to microTalk via Apple Podcasts, Google Podcasts, Android, Email or RSS and never miss an episode!

    • 1 hr 5 min
    062: The Rules of Attraction: Bacterial Magnetosomes with Arash Komeili

    062: The Rules of Attraction: Bacterial Magnetosomes with Arash Komeili

    Some bacteria have the amazing ability to orient themselves using the earth’s magnetic field, due to the presence of an intracellular organelle called the magnetosome, which are estimated to have evolved 3 billion years ago.  
    Dr. Arash Komeili is a Professor at the University of California Berkeley who studies bacterial magnetosomes. 
    Dr. Komeili talks about how magnetotactic bacteria were discovered, how the earth’s magnetic field orients the bacteria in the aquatic environment, whether a Martian meteorite had bacterial magnetite in it, how bacterial magnetosomes can be exploited for targeting cancer cells, and whether bacterial magnetosomes could be used to generate energy.  
    microTalk was pleased to be joined by Dr. Marvin Whiteley (Georgia Tech) when this podcast was recorded at the ASM Microbe 2019 conference in San Francisco, CA.
    The microCase for listeners to solve is about Randy Farmer, a businessman who comes down with an uncomfortable disease after a trip to Bangkok.
    Participants: Karl Klose, Ph.D. (UTSA) Arash Komeili, Ph.D. (University of California Berkeley) Janakiram Seshu, Ph.D. (UTSA) Mylea Echazarreta (UTSA) Marvin Whiteley, Ph.D. (Georgia Institute of Technology)

    • 52 min
    061: TB or not TB? That is the Question… for Bill Jacobs

    061: TB or not TB? That is the Question… for Bill Jacobs

    Tuberculosis (TB) remains one of the most prevalent infectious diseases in the world, with approximately 10 million people becoming sick and 1.5 million people dying every year from Mycobacterium tuberculosis infection.
    Dr. William Jacobs is a Professor at the Albert Einstein College of Medicine and member of the National Academy of Sciences who studies M. tuberculosis.
    TB is notoriously difficult to treat, due to the slow growth and persistence of the bacteria in the lungs, requiring extensive antibiotic treatment over a long period of time.
    Dr. Jacobs talks about the history of tuberculosis (“consumption”) in humans, how M. tuberculosis can hang out in the lungs for an entire lifetime, how slow growth is a bacterial strategy to avoid killing by antibiotics, how growth in armadillos is required to study the closely related M. leprae (causes leprosy), just how scary drug-resistant TB strains are, and how dirt from the Bronx Zoo was hiding a genetic tool that was a game-changer for the study of TB.
    The microCase for listeners to solve is about Ella Copta and Lana Jorgia, two internet vloggers who become ill after visiting an African shaman.
    Participants:
    Karl Klose, Ph.D. (UTSA)
    William Jacobs, Ph.D. (Albert Einstein College of Medicine)
    Janakiram Seshu, Ph.D. (UTSA)
    Mylea Echazarreta (UTSA)
    Abigail Blaschke (UTSA)
    Jacobi Brown (UTSA)

    • 48 min

Customer Reviews

4.9 out of 5
16 Ratings

16 Ratings

Bjartur108 ,

Where is Dr. Seshu?

I’m a microbiology PhD student and I love the podcast! The mystery cases are especially fun. But is it ever NOT Micro-Seshu who hosts? I want to hear from his alter ego once in a while!

tchen18 ,

Great

I am working on medical mycology and really love this podcast.

Freddy Sea ,

Brilliant topics

Very interesting with great scientists.

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