25 min

Mapping the Human Proteoform: The Future of Cancer Therapy Think Like a Scientist

    • Science

What will be the future of cancer therapy? In this episode I discuss the major key takeaways from the recently published paper and established project: "The Human Proteoform Project: Defining the human proteome." 

Ranging from stories of a six year old girl, among many, who was cured from childhood cancer using immunotherapy. We've known that strategies like chemotherapy and immune-supression like insulin have only been partially successful. What have we been missing this whole time? I discuss how the emerging field of precision medicine takes into account the other half of what has been missed—which will increase the efficacy and aid the development of novel therapeutics that are both preventative and curative. 



The Human Proteoform Project: Defining the human proteome: 

https://doi.org/10.1126/sciadv.abk0734



Differences between germline genomes of monozygotic twins:

https://www.nature.com/articles/s41588-020-00755-1

What will be the future of cancer therapy? In this episode I discuss the major key takeaways from the recently published paper and established project: "The Human Proteoform Project: Defining the human proteome." 

Ranging from stories of a six year old girl, among many, who was cured from childhood cancer using immunotherapy. We've known that strategies like chemotherapy and immune-supression like insulin have only been partially successful. What have we been missing this whole time? I discuss how the emerging field of precision medicine takes into account the other half of what has been missed—which will increase the efficacy and aid the development of novel therapeutics that are both preventative and curative. 



The Human Proteoform Project: Defining the human proteome: 

https://doi.org/10.1126/sciadv.abk0734



Differences between germline genomes of monozygotic twins:

https://www.nature.com/articles/s41588-020-00755-1

25 min

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