660 episodes

Hi, I'm Chris Masterjohn and I have a PhD in Nutritional Sciences. I am an entrepreneur in all things fitness, health, and nutrition. In this show I combine my scientific expertise with my out-of-the-box thinking to translate complex science into new, practical ideas that you can use to help yourself on your journey to vibrant health. This show will allow you to master the science of nutrition and apply it to your own life like a pro.

Mastering Nutrition Chris Masterjohn, PhD

    • Health & Fitness
    • 4.6 • 397 Ratings

Hi, I'm Chris Masterjohn and I have a PhD in Nutritional Sciences. I am an entrepreneur in all things fitness, health, and nutrition. In this show I combine my scientific expertise with my out-of-the-box thinking to translate complex science into new, practical ideas that you can use to help yourself on your journey to vibrant health. This show will allow you to master the science of nutrition and apply it to your own life like a pro.

    How do I consume omega-3 without hurting my omega-6 status? | Masterjohn Q&A Files #316

    How do I consume omega-3 without hurting my omega-6 status? | Masterjohn Q&A Files #316

    Question: If I don’t want to hurt my omega 6 status through my omega 3 intake, how do I do that? Is it simply a question of taking them at separate times? Or is it a question of dose? And if it is a question of dose, how do I know when to start eating fish and taking my omega 3 supplement again?
    Short Answer: How they are combined in meals is not important, but it is important not to have too much EPA in cell membranes relative to arachidonic acid, and this is driven by cumulative intake over years. For someone who has consumed too much EPA for many years, the best approach is to eat liver and egg yolks for arachidonic acid while getting omega-3s from a DHA supplement and not from fish, fish oil, or fish liver oil.
    This is a clip from a live Q&A session open to CMJ Masterpass members. In addition to this episode, you can access two other free samples using this link:
    https://chrismasterjohnphd.substack.com/p/questions-on-plant-compounds-and
    In that batch of free episodes you will also find the answers to these questions:
    Can plant foods and their phytochemicals be used to reduce arterial plaque?
    If I have a hereditary weakness in breaking down branched-chain amino acids, what cofactors do I need to consider, and do I need to restrict my protein when losing weight?
    If you want to become a Masterpass member so you can participate in the next live Q&A, or so you can have access to the complete recording and transcript of each Q&A session, you can save 10% off the subscription price for as long as you remain a member by using this link to sign up:
    https://chrismasterjohnphd.substack.com/qanda
    Learn more about the Masterpass here:
    https://chrismasterjohnphd.substack.com/about
    This snippet is from the January 21, 2023 AMA. The full recording and transcript is reserved for Masterpass members. Here is a preview of what’s included:
    Can plant foods and their phytochemicals be used to reduce arterial plaque?
    If I have a hereditary weakness in breaking down branched-chain amino acids, what cofactors do I need to consider, and do I need to restrict my protein when losing weight?
    Could carnitine help a fatty acid oxidation disorder?
    Should anti-inflammatories be taken away from workouts?
    How does vitamin C affect autoimmune disease?
    Folate form and purines
    Can methylene blue help the respiratory chain?
    Best references for omega-3 and inflammation resolution?
    Smoothies and blood sugar
    Is transdermal magnesium oil effective for osteoarthritis?
    Why do K2 and Mg help my nerve pain?
    Should I separate my potassium benzoate and vitamin C supplements?
    The best and most simple comprehensive micronutrient panel.
    How much K2 is needed in pregnancy?
    How do I accentuate the fasting-feeding cycle?
    Could K2 help with environmental pollution?
    Why do shoulders crack when we get older?
    Why do I react poorly to anti-inflammatory foods?
    Here’s a link to the full AMA: https://chrismasterjohnphd.substack.com/p/recording-and-transcript-of-the-january 

    Access the show notes, transcript, and comments here.

    • 24 min
    Energy Metabolism Governs Everything

    Energy Metabolism Governs Everything

    That was not an exaggeration. Everything.

    In this podcast I cover why riboflavin abolished my allergies, why a respiratory chain disorder could cause an autoimmune condition, and why a hypothetical athlete who went keto to take home the silver might be able to use thiamin to take home the gold.
    Most importantly, I cover why these are idiosyncratic needs, not general rules.
    The generalizable principle is that nothing is more central to life and health than energy.
    Read the written version with links here:
    https://chrismasterjohnphd.substack.com/p/energy-metabolism-governs-everything
    Get the methylation protocol here: 
    https://chrismasterjohnphd.substack.com/p/mthfr-protocol
    Check out my course on energy metabolism here:
    https://chrismasterjohnphd.substack.com/p/masterclass-with-masterjohn-energy

    • 42 min
    Can plant foods and their phytochemicals be used to reduce arterial plaque? | Masterjohn Q&A Files #315

    Can plant foods and their phytochemicals be used to reduce arterial plaque? | Masterjohn Q&A Files #315

    Question: Can plant foods and their phytochemicals be used to reduce arterial plaque?
    Short Answer: Yes, but if you don’t have specific intolerances to plant compounds the best thing to do is simply aim to meet your vitamin and mineral targets from a diet rich in fruits, vegetables, herbs, and spices, rather than trying to use specific plant compounds from specific studies in any specific amount.
    This is a clip from a live Q&A session open to CMJ Masterpass members. In addition to this episode, you can access two other free samples using this link:
    https://chrismasterjohnphd.substack.com/p/questions-on-plant-compounds-and
    In that batch of free episodes you will also find the answers to these questions:
    How do I consume omega-3 without hurting my omega-6 status?
    If I have a hereditary weakness in breaking down branched-chain amino acids, what cofactors do I need to consider, and do I need to restrict my protein when losing weight?
    If you want to become a Masterpass member so you can participate in the next live Q&A, or so you can have access to the complete recording and transcript of each Q&A session, you can save 10% off the subscription price for as long as you remain a member by using this link to sign up:
    https://chrismasterjohnphd.substack.com/qanda
    Learn more about the Masterpass here:
    https://chrismasterjohnphd.substack.com/about
    This snippet is from the January 21, 2023 AMA. The full recording and transcript is reserved for Masterpass members. Here is a preview of what’s included:
    Can plant foods and their phytochemicals be used to reduce arterial plaque?
    How do I consume omega-3 without hurting my omega-6 status?
    If I have a hereditary weakness in breaking down branched-chain amino acids, what cofactors do I need to consider, and do I need to restrict my protein when losing weight?
    Could carnitine help a fatty acid oxidation disorder?
    Should anti-inflammatories be taken away from workouts?
    How does vitamin C affect autoimmune disease?
    Folate form and purines
    Can methylene blue help the respiratory chain?
    Best references for omega-3 and inflammation resolution?
    Smoothies and blood sugar
    Is transdermal magnesium oil effective for osteoarthritis?
    Why do K2 and Mg help my nerve pain?
    Should I separate my potassium benzoate and vitamin C supplements?
    The best and most simple comprehensive micronutrient panel.
    How much K2 is needed in pregnancy?
    How do I accentuate the fasting-feeding cycle?
    Could K2 help with environmental pollution?
    Why do shoulders crack when we get older?
    Why do I react poorly to anti-inflammatory foods?
    Here’s a link to the full AMA: https://chrismasterjohnphd.substack.com/p/recording-and-transcript-of-the-january

    Access the show notes, transcript, and comments here.
     

    • 28 min
    What to Do About Twitching | Masterjohn Q&A Files #314

    What to Do About Twitching | Masterjohn Q&A Files #314

    Question: What can be done about twitching?

    Short Answer: Most twitching will be driven by glutamate/GABA balance or acetylcholine regulation, and the most likely nutritional issues are any of the electrolytes or any factor that influences energy metabolism. The best way to address it is to consider the conditions that influence it and then trial and error your way through each potential nutritional issue in order of which ones make the most sense for your individual case first.

    This is a clip from a live Q&A session open to CMJ Masterpass members. In addition to this episode, you can access two other free samples using this link:

    https://chrismasterjohnphd.substack.com/p/questions-on-phosphatidylcholine

    In that batch of free episodes you will also find the answers to these questions:
    Phosphatidylcholine and TMAO Vitamin K2 and Undercarboxylated Osteocalcin If you want to become a Masterpass member so you can participate in the next live Q&A, or so you can have access to the complete recording and transcript of each Q&A session, you can save 10% off the subscription price for as long as you remain a member by using this link to sign up:

    https://chrismasterjohnphd.substack.com/qanda

    Learn more about the Masterpass here:

    https://chrismasterjohnphd.substack.com/about

    This snippet is from the December 14, 2022 AMA. The full recording and transcript is reserved for Masterpass members. Here is a preview of what’s included:
    Inositol, What Is It Good For? If I am at risk of heart disease, and phosphatidylcholine raises my TMAO, should I stop the supplement? If undercarboxylated osteocalcin (ucOCN) has health benefits and vitamin K2 decreases it, what does that mean for vitamin K2 supplementation? Maragen Calcium Could slow methylation cause high selenium levels? My current thoughts on cholesterol and heart disease If I already have oxidative stress, what ducks should I have in a row before supplementing with iron? Is it safe to take eight milligrams of zinc daily without copper? What to do about developing sensitivities to an increasingly broad range of foods? What else to do about hemochromatosis besides phlebotomy? If gestational diabetes is just a biotin deficiency, why are women who are insulin resistant prior to pregnancy at higher risk for it, including women with PCOS? What to do about chronically elevated amylase and lipase? What to do about a non-drinker having very high GGT and occasionally high ALT? What are the most common vitamin and mineral deficiencies? What are the best supplements, vitamins, and minerals for OCD and depression? What is the connection between low pyruvate and high ketones? Is high LDL a concern if the carotid IMT and coronary calcium scan are clear?  Do I trust food allergy tests? Here’s a link to the full AMA: https://chrismasterjohnphd.substack.com/p/recording-and-transcript-of-the-december
    Access the show notes, transcript, and comments here.

    • 7 min
    Can Biotin Help Detoxify Oxalate?

    Can Biotin Help Detoxify Oxalate?

    This is a hypothesis that may reconcile some anecdotes and has many hints suggested in the enzymological literature.
    First, make sure you get my MTHFR Protocol, my free 7-page quick guide to optimizing and personalizing your methylation status, here:
     https://chrismasterjohnphd.com/blog/2019/03/01/start-here-for-mthfr-and-methylation
    For the written version with references, as well as the 58 comments, including from Susan Owens, head over to Substack:
    https://chrismasterjohnphd.substack.com/p/can-biotin-help-detoxify-oxalate 
     

    • 40 min
    Vitamin K2 and Undercarboxylated Osteocalcin | Masterjohn Q&A Files #313

    Vitamin K2 and Undercarboxylated Osteocalcin | Masterjohn Q&A Files #313

    Question: If undercarboxylated osteocalcin has health benefits, and vitamin K2 decreases it, what does that mean for K2 supplementation?

    Short Answer: Vitamin K2 helps secure osteocalcin in bone matrix, where it is decarboxylated and released as an endocrine hormone in response to certain stimuli. When released, it acts to optimize insulin secretion, insulin sensitivity, fuel use during exercise, and male testosterone.

    This is a clip from a live Q&A session open to CMJ Masterpass members. In addition to this episode, you can access two other free samples using this link:

    https://chrismasterjohnphd.substack.com/p/questions-on-phosphatidylcholine

    In that batch of free episodes you will also find the answers to these questions:
    Phosphatidylcholine and TMAO What to Do About Twitching If you want to become a Masterpass member so you can participate in the next live Q&A, or so you can have access to the complete recording and transcript of each Q&A session, you can save 10% off the subscription price for as long as you remain a member by using this link to sign up:

    https://chrismasterjohnphd.substack.com/qanda

    Learn more about the Masterpass here:

    https://chrismasterjohnphd.substack.com/about
    This snippet is from the December 14, 2022 AMA. The full recording and transcript is reserved for Masterpass members. Here is a preview of what’s included:
    Inositol, What Is It Good For? If I am at risk of heart disease, and phosphatidylcholine raises my TMAO, should I stop the supplement? Maragen Calcium Could slow methylation cause high selenium levels? My current thoughts on cholesterol and heart disease If I already have oxidative stress, what ducks should I have in a row before supplementing with iron? Is it safe to take eight milligrams of zinc daily without copper? What to do about developing sensitivities to an increasingly broad range of foods? What else to do about hemochromatosis besides phlebotomy? If gestational diabetes is just a biotin deficiency, why are women who are insulin resistant prior to pregnancy at higher risk for it, including women with PCOS? What to do about chronically elevated amylase and lipase? What to do about a non-drinker having very high GGT and occasionally high ALT? What are the most common vitamin and mineral deficiencies? What are the best supplements, vitamins, and minerals for OCD and depression? What is the connection between low pyruvate and high ketones? Is high LDL a concern if the carotid IMT and coronary calcium scan are clear?  An algorithm to fix twitching Do I trust food allergy tests? Here’s a link to the full AMA: https://chrismasterjohnphd.substack.com/p/recording-and-transcript-of-the-december
    Access the show notes, transcript, and comments here.

    • 17 min

Customer Reviews

4.6 out of 5
397 Ratings

397 Ratings

robeeenz ,

This just became my favorite podcast

I’ve been to 14 doctors who don’t understand ferritin or riboflavin- I know this podcast is not medical advice but it is imperative that if you want optimal health you must educate yourself!! This is a great podcast to start!

malfoxley ,

Great show!

Chris, host of the podcast, highlights all aspects of health, nutrition and more in this can’t miss podcast! The host and expert guests offer insightful advice and information that is helpful to anyone that listens!

Sandyjohnsn ,

Prepare before you record

I’m a health and nutrition nut and love learning. But 5 min in to your podcast and I had to turn it off it was annoying me so much. So much dead air while you tried to read a study on the topic of psyllium. It’s like you were reading the info for the first time while recording. Dude. Read the studies and make some notes and THEN record your podcast to bring the info to your audience. Geeze… most painful podcast I’ve ever heard.

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