416 episodes

Hi, I'm Chris Masterjohn and I have a PhD in Nutritional Sciences. I am an entrepreneur in all things fitness, health, and nutrition. In this show I combine my scientific expertise with my out-of-the-box thinking to translate complex science into new, practical ideas that you can use to help yourself on your journey to vibrant health. This show will allow you to master the science of nutrition and apply it to your own life like a pro.

Mastering Nutrition Chris Masterjohn, PhD

    • Alternative Health
    • 4.7 • 322 Ratings

Hi, I'm Chris Masterjohn and I have a PhD in Nutritional Sciences. I am an entrepreneur in all things fitness, health, and nutrition. In this show I combine my scientific expertise with my out-of-the-box thinking to translate complex science into new, practical ideas that you can use to help yourself on your journey to vibrant health. This show will allow you to master the science of nutrition and apply it to your own life like a pro.

    COVID Conversations: Gabriela Gomes on Herd Immunity

    COVID Conversations: Gabriela Gomes on Herd Immunity

    I don't usually interview people on my podcast, but this is an important exception and I'd appreciate it if you'd share it far and wide.
    Here's the YouTube version:
    COVID Conversations: Gabriela Gomes on Herd Immunity
    Gabriela Gomes is Professor of Mathematics and Statistics at University of Strathclyde Glasgow and corresponding author of the recent paper, "Herd immunity thresholds for SARS-CoV-2 estimated from unfolding epidemics," one of the papers arguing that the herd immunity threshold is on the order of 10-20% in the European communities they studied rather than the 60-80% more commonly cited, and she's here to talk about herd immunity and COVID-19.
    Here's a list of topics we covered:
    00:00:01 Introduction
    00:01:28 Gabriela's body of research showing the importance of individual variation in susceptibility to infectious diseases.
    00:04:25 Conventional models that don't take into account individual variation overestimate the size of epidemics and overestimate the effect of interventions.
    00:05:21 How has her research been received by her colleagues?
    00:09:30 The evolution of immunity has to be through the action of natural selection on variation, making it logically necessary that variation exists.
    00:11:54 Nutrition scientists underestimated variation in nutritional requirements but have been much more receptive than infectious disease epidemiologists to incorporating it into their models.
    00:15:51 The ability to identify a single necessary factor in infectious disease spread has biased the field toward a ground-up mechanistic model to vet the inclusion of variables.
    00:22:34 What is herd immunity?
    00:26:11 Tuberculosis disappeared because socioeconomic conditions improved.
    00:29:06 Until the vaccine, measles cycled in and out of herd immunity as new infants entered the susceptible population.
    00:31:13 Measles is much more transmissible than SARS-CoV-2.
    00:32:21 SARS was contained before it had a chance to spread.
    00:34:08 Herd immunity is not the end of concern about a disease.
    00:34:33 The herd immunity threshold for COVID will be crossed many times, but crossing it the first time is the end of the "pandemic phase."
    00:39:16 The seasonality of the flu is influenced not only by weather and social patterns that influence transmissibility, but also by cyclically crossing in and out of herd immunity. Viral mutations can be the trigger to temporarily cycle out of herd immunity.
    00:46:57 Why conventional herd immunity threshold calculations say the threshold is 60-80% for COVID, but why Gabriela's model says 10-20%.
    00:51:45 How do we know what the degree of variation is?
    00:54:56 Gabriela's conclusions are similar to those reached by other researchers when looking at NYC and Chicago.
    00:56:48 As long as susceptibility is correlated to infectiousness, natural infections will remove the most infectious people early on.
    01:01:26 Is it possible that lockdowns and social distancing are solely responsible for everything we attribute to herd immunity?
    01:08:30 How likely is it that fading immunity and reinfection would render the herd immunity model useless?
    01:11:19 What does the New York City data tell us about herd immunity and reinfection?
    01:15:32 What does Spain's second wave tell us?
    01:19:21 We discuss Harvard Professor Miguel Hernán's suggestion on Twitter that NYC is doing so much better than Madrid because NYC had superior testing, contact tracing, and phased reopening.
    01:23:16 Misunderstanding herd immunity has huge economic consequences.
    01:25:13 Should we be looking at cases, hospitalizations, deaths, or seroprevalence as our primary metric?
    01:35:28 We discuss University of Minnesota epidemiologist Michael Osterholm's suggestion that scientists modeling a 20% herd immunity threshold are "not connected with real-world thinking" and that the much higher infection rates in prisons and

    • 1 hr 59 min
    COVID-19: Are We Already Reaching Herd Immunity?

    COVID-19: Are We Already Reaching Herd Immunity?

    Read the written version here, with links to the original references:
    https://chrismasterjohnphd.com/covid-19/are-we-already-reaching-herd-immunity
    Sign up for the free newsletter: https://chrismasterjohnphd.com/covid19-updates 
    Discuss this in the Masterpass Free Forum at https://chrismasterjohnphd.com/discuss 
    Discuss this in the Coronavirus Forum when you purchase the guide, pre-order my upcoming book, or join the CMJ Masterpass.
    Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: https://chrismasterjohnphd.com/coronavirus 
    Get the guide for free when pre-ordering my Vitamins and Minerals 101 book: https://chrismasterjohnphd.com/book 
    Get the guide for free and get 30-50% off the pre-orders of my book when you sign up for the CMJ Masterpass: https://chrismasterjohnphd.com/masterpass 
    DISCUSS!
    Here are three ways to discuss this topic, including asking me questions and getting a response:
    The Masterpass FREE Forum. This forum is free and open to anyone to participate. Anything related to health and nutrition, including all aspects of the coronavirus, is welcome. I will do my best to participate several times a week, though I expect this to eventually be very large and may at some point have to participate on a weekly basis if it starts to take on a life of its own. Join for free at chrismasterjohnphd.com/discuss
    The Coronavirus Forum. This is for anyone who purchases The Food and Supplement Guide for the Coronavirus, pre-orders my upcoming Vitamins and Minerals 101 book, or joins the CMJ Masterpass (if you join, use the coupon code COVID19 for 10% off the membership price). This forum is dedicated specifically to the coronavirus, has subsections based on topics (nutrition, medicine, lifestyle, mechanisms of disease), and has a section where the archive version of this newsletter is directly linked and each newsletter can be discussed as an individual thread. I consistently participate in this forum 3-5 times a week. Purchase the guide at chrismasterjohnphd.com/coronavirus
    The Masterpass Discussion Group. Preserved for those who join the CMJ Masterpass, it's the best place to ask me questions in a fairly intimate environment and get a rapid response. All topics I cover are fair game, and I consistently participate approximately five times per week. The Masterpass also has monthly live Zoom Q&As that are even more intimate. Join the Masterpass at chrismasterjohnphd.com/masterpass
    SUPPORT
    These research updates are made possible by purchases of The Food and Supplement Guide to the Coronavirus. The guide contains my most up-to-date conclusions about what we should be doing for nutritional and herbal support on top of hygiene and social distancing for added protection. Due to the absence of randomized controlled trials testing nutritional or herbal prevention, these are my best guesses for what is likely to work without significant risk of harm, based on the existing science. By purchasing the guide, you are enabling me to continue devoting my skills to the most important issue we now face. I am genuinely grateful for your contribution. You can purchase a copy at chrismasterjohnphd.com/coronavirus
    You can get the guide for free if you pre-order my upcoming book, Vitamins and Minerals 101: How to Get the Nutrients You Need on Any Diet (to be released when the COVID-19 crisis subsides). You can pre-order it at chrismasterjohnphd.com/book
    You can also get the guide free when you join the CMJ Masterpass, which is meant to help people with significant health and wellness expenditures consistently save money by returning marketing cost of the companies involved back to the members as rebates. A membership also saves you 30% on pre-orders of the paperback and 50% on pre-orders of the digital versions of my book. You can sign up at chrismasterjohnphd.com/masterpass
    SUBSC

    • 52 min
    Why would blood glucose go up on a low-carb diet? | Masterjohn Q&A Files #131

    Why would blood glucose go up on a low-carb diet? | Masterjohn Q&A Files #131

    Question: Why would blood glucose go up on a low-carb diet?
    When you're adapted to low insulin levels with lower GLUT expression, but you want to get glucose into muscle, you're going to need higher blood glucose levels to do it.
    I think elevated blood glucose is sufficiently known to be pathological that it would be unwise to assume the sort of more generous interpretation of that as a physiological response. I think it would be a much better approach to do what you need to do to get your blood glucose levels into the healthy range. Otherwise, I think it's quite a gamble to presume innocence of that elevated blood glucose.
    This Q&A can also be found as part of a much longer episode, here.

    If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.
    There are two ways to discuss this episode:
    Discuss it in The Masterpass FREE Forum, which is freely open to everyone, at https://chrismasterjohnphd.com/discuss
    If you’re a Masterpass member, discuss it in the Masterpass Discussion Group, found in your dashboard.
    DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

    • 2 min
    Why do thyroid levels drop on a low-carb diet? | Masterjohn Q&A Files #130

    Why do thyroid levels drop on a low-carb diet? | Masterjohn Q&A Files #130

    Question: Why do thyroid levels drop on a low-carb diet?
    So insulin and leptin are both positive regulators of thyroid hormone, production, and conversion. And generally I do think there's probably a larger effect from thyroid production than peripheral conversion. I'm not too sure about that, but insulin does directly regulate thyroid. It has TSH-like effects on the thyroid gland. It doesn't replicate all of TSH's effects, but it does replicate a portion of them. So basically, more or less, have like TSH amplification with insulin.

    This Q&A can also be found as part of a much longer episode, here.
    If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.

    There are two ways to discuss this episode:
    Discuss it in The Masterpass FREE Forum, which is freely open to everyone, at https://chrismasterjohnphd.com/discuss  If you’re a Masterpass member, discuss it in the Masterpass Discussion Group, found in your dashboard. DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

    • 1 min
    How Diabetes, Like Sugar, May Fuel Viral Growth

    How Diabetes, Like Sugar, May Fuel Viral Growth

    Sign up for the free newsletter: https://chrismasterjohnphd.com/covid19-updates 
    Discuss this in the Masterpass Free Forum at https://chrismasterjohnphd.com/discuss 
    Discuss this in the Coronavirus Forum when you purchase the guide, pre-order my upcoming book, or join the CMJ Masterpass.
    Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: https://chrismasterjohnphd.com/coronavirus 
    Get the guide for free when pre-ordering my Vitamins and Minerals 101 book: https://chrismasterjohnphd.com/book 
    Get the guide for free and get 30-50% off the pre-orders of my book when you sign up for the CMJ Masterpass: https://chrismasterjohnphd.com/masterpass 
    DISCUSS!
    Here are three ways to discuss this topic, including asking me questions and getting a response:
    The Masterpass FREE Forum. This forum is free and open to anyone to participate. Anything related to health and nutrition, including all aspects of the coronavirus, is welcome. I will do my best to participate several times a week, though I expect this to eventually be very large and may at some point have to participate on a weekly basis if it starts to take on a life of its own. Join for free at chrismasterjohnphd.com/discuss
    The Coronavirus Forum. This is for anyone who purchases The Food and Supplement Guide for the Coronavirus, pre-orders my upcoming Vitamins and Minerals 101 book, or joins the CMJ Masterpass (if you join, use the coupon code COVID19 for 10% off the membership price). This forum is dedicated specifically to the coronavirus, has subsections based on topics (nutrition, medicine, lifestyle, mechanisms of disease), and has a section where the archive version of this newsletter is directly linked and each newsletter can be discussed as an individual thread. I consistently participate in this forum 3-5 times a week. Purchase the guide at chrismasterjohnphd.com/coronavirus
    The Masterpass Discussion Group. Preserved for those who join the CMJ Masterpass, it's the best place to ask me questions in a fairly intimate environment and get a rapid response. All topics I cover are fair game, and I consistently participate approximately five times per week. The Masterpass also has monthly live Zoom Q&As that are even more intimate. Join the Masterpass at chrismasterjohnphd.com/masterpass
    SUPPORT
    These research updates are made possible by purchases of The Food and Supplement Guide to the Coronavirus. The guide contains my most up-to-date conclusions about what we should be doing for nutritional and herbal support on top of hygiene and social distancing for added protection. Due to the absence of randomized controlled trials testing nutritional or herbal prevention, these are my best guesses for what is likely to work without significant risk of harm, based on the existing science. By purchasing the guide, you are enabling me to continue devoting my skills to the most important issue we now face. I am genuinely grateful for your contribution. You can purchase a copy at chrismasterjohnphd.com/coronavirus
    You can get the guide for free if you pre-order my upcoming book, Vitamins and Minerals 101: How to Get the Nutrients You Need on Any Diet (to be released when the COVID-19 crisis subsides). You can pre-order it at chrismasterjohnphd.com/book
    You can also get the guide free when you join the CMJ Masterpass, which is meant to help people with significant health and wellness expenditures consistently save money by returning marketing cost of the companies involved back to the members as rebates. A membership also saves you 30% on pre-orders of the paperback and 50% on pre-orders of the digital versions of my book. You can sign up at chrismasterjohnphd.com/masterpass
    SUBSCRIBE
    This series is based on my free daily newsletter, COVID-19 Research Updates. As a result of the time it takes to produce an video or podcast from

    • 21 min
    Is hydrogen sulfide produced in the gut a bad thing, and what to do about it? | Masterjohn Q&A Files #129

    Is hydrogen sulfide produced in the gut a bad thing, and what to do about it? | Masterjohn Q&A Files #129

    Question: Is hydrogen sulfide produced in the gut a bad thing, and what to do about it?

    I agree that most people that have this problem have some kind of deranged sulfur metabolism, but I don't see why that makes it a physiological adaptation rather than a pathological condition. The correlation is probably a direct result of the predominance of sulfur-metabolizing bacteria in the gut, which is a bad thing that is actually causing the derangement of sulfur metabolism.

    Well, you could go the antibiotic route. And I think metronidozole, and let me see if I can dig this up quickly because I have done a lot of research on this issue for one of my clients. Okay. So from the research I was looking at, metronidozole is very effective against sulfur-metabolizing bacteria. But isn't that reliably delivered to the stool and maybe could be used as an enema. But I think generally, it is used. And then I think there's one other one that's sometimes used. I forgot what the other one is. I think it's... Okay. I can't find it. Anyway, you can go the antibiotic route under the guidance of a prescribing specialist.

    This Q&A can also be found as part of a much longer episode, here.
    If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.

    There are two ways to discuss this episode:
    Discuss it in The Masterpass FREE Forum, which is freely open to everyone, at https://chrismasterjohnphd.com/discuss  If you’re a Masterpass member, discuss it in the Masterpass Discussion Group, found in your dashboard. DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

    • 6 min

Customer Reviews

4.7 out of 5
322 Ratings

322 Ratings

Marisa J2 ,

LOVE IT!!!

Chris is awesome, he offers amazing insight and information that is really helpful for listeners!

KSSLC ,

Detailed Covid 19 information

Thanks Chris for the information regarding Covid 19. I am keeping notes. In the event I or someone I know ends is hospitalized I will know what to ask the healthcare professionals and what to keep an eye on. Your podcasts are precise and informative. Information is power and I feel like I have (at least a little bit) of control over this virus.

Clarisse Gomez ,

Awesome Podcast!!!

Chris, host of the Mastering Nutrition podcast, highlights all aspects of health, wellness and more in this can’t miss podcast! The host and expert guests offer insightful advice and information that is helpful to anyone that listens!

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