128 episodes

Each week, MIB Agents talks with the leaders and innovators in osteosarcoma surgery, research, treatment and advocacy. Questions are taken during the webinar and are included in each podcast. More information is available at www.mibagents.org

MIB Agents OsteoBites Ann Graham

    • Health & Fitness
    • 5.0 • 4 Ratings

Each week, MIB Agents talks with the leaders and innovators in osteosarcoma surgery, research, treatment and advocacy. Questions are taken during the webinar and are included in each podcast. More information is available at www.mibagents.org

    Immunological Mechanisms of Cancer Defense

    Immunological Mechanisms of Cancer Defense

    Ming Li, PhD, is Member of the Immunology Program at Memorial Sloan Kettering Cancer Center and Professor at Weill Cornell Graduate School of Medical Sciences. His laboratory studies immune regulation and its relevance to diseases including cancer. Recent work has focused on the signaling, metabolic, and transcriptional mechanisms of T cell regulation as well as tumor-elicited innate and adaptive immune responses, and how this knowledge can be translated for novel cancer immunotherapy. Dr. Li received his PhD in Biological Sciences from Columbia University, and postdoctoral training at Yale University. Dr. Li is an American Academy of Arts and Sciences (AAAS) Fellow and has received a number of honors including a Howard Hughes Medical Institute (HHMI) Faculty Scholar Award, a Rita Allen Foundation Scholar Award, an American Cancer Society Scholar award, and the 2016 American Association of Immunologists (AAI)-BD Bioscience Investigator Award for outstanding contributions to the field of immunology.

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    What We Do at MIB Agents: PROGRAMS: End-of-Life MISSIONS Gamer Agents Agent Writers Prayer Agents Healing Hearts - Bereaved Parent and Sibling Support Ambassador Agents - Peer Support Warrior Mail Young Adult Survivorship Support Group EDUCATION for physicians, researchers and families: OsteoBites, weekly webinar & podcast with thought leaders and innovators in Osteosarcoma MIB Book: Osteosarcoma: From our Families to Yours RESEARCH: Annual MIB FACTOR Research Conference Funding multiple $100,000 and $50,000 grants annually for OS research MIB Testing & Research Directory The Osteosarcoma Project partner with Broad Institute of MIT and Harvard ... Kids are still dying with 40+ year old treatments. Help us MakeItBetter. https://www.mibagents.org​ Help support MIB Agents, Donate here https://give-usa.keela.co/embed/YAipuSaWxHPJP7RCJ SUBSCRIBE for all the Osteosarcoma Intel

    • 59 min
    osTEAo: Long Term Osteosarcoma Survivors: Where They Were and Where They Are Now

    osTEAo: Long Term Osteosarcoma Survivors: Where They Were and Where They Are Now

    In this episode, OsteoWarriors Camille and Mia interview three long term osteosarcoma survivors.  Hear from Maeve, Sloane, and Eva about their osteosarcoma stories, what the most difficult hurdles have been for them, and what advice they would give themselves if they could go back in time.  While osteosarcoma is a tough journey for most patients, this episode will fill you with hope.

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    What We Do at MIB Agents: PROGRAMS: End-of-Life MISSIONS Gamer Agents Agent Writers Prayer Agents Healing Hearts - Bereaved Parent and Sibling Support Ambassador Agents - Peer Support Warrior Mail Young Adult Survivorship Support Group EDUCATION for physicians, researchers and families: OsteoBites, weekly webinar & podcast with thought leaders and innovators in Osteosarcoma MIB Book: Osteosarcoma: From our Families to Yours RESEARCH: Annual MIB FACTOR Research Conference Funding multiple $100,000 and $50,000 grants annually for OS research MIB Testing & Research Directory The Osteosarcoma Project partner with Broad Institute of MIT and Harvard ... Kids are still dying with 40+ year old treatments. Help us MakeItBetter. https://www.mibagents.org​ Help support MIB Agents, Donate here https://give-usa.keela.co/embed/YAipuSaWxHPJP7RCJ SUBSCRIBE for all the Osteosarcoma Intel

    • 1 hr 5 min
    Cabozantinib as a Maintenance Therapy to Prevent Recurrence of High-Risk Pediatric Solid Tumors

    Cabozantinib as a Maintenance Therapy to Prevent Recurrence of High-Risk Pediatric Solid Tumors

    Nilay Shah, MD is a clinician-scientist and Associate Professor in the Division of Hematology/Oncology/BMT at Nationwide Children’s Hospital. His primary clinical focus is on pediatric solid tumors, including neuroblastomas, tumors of the kidneys, and rare solid tumors of childhood. His research focuses on the molecular drivers of pediatric cancers and how new treatment approaches can be taken to better target those drivers. In this role, he works to identify new uses of currently available anticancer treatments, including drugs originally developed for use against cancers in adults. He serves as Associate Director for Liver Tumor, Kidney Tumor, Germ Cell, and Neuroblastoma Targeted Therapies, and is currently the Sponsor and Study Principal Investigator the CaboMain trial, a Phase 2 study evaluating the efficacy of the oral anticancer agent cabozantinib as a maintenance therapy for ultra-high-risk solid tumors.



    He also serves as co-director of the Cancer Genetics Program. This program serves to advance the use of genetic and genomic evaluations for the benefits of patients. In this role, he sees patients in the Cancer Predisposition Clinic for evaluation, surveillance, and management of patients with genetic alterations that predispose to cancer development. He also consults on patients for precision oncology, partnering with the Institute for Genomic Medicine to identify therapeutic approaches based on patient tumor and germline genomics.



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    What We Do at MIB Agents: PROGRAMS: End-of-Life MISSIONS Gamer Agents Agent Writers Prayer Agents Healing Hearts - Bereaved Parent and Sibling Support Ambassador Agents - Peer Support Warrior Mail Young Adult Survivorship Support Group EDUCATION for physicians, researchers and families: OsteoBites, weekly webinar & podcast with thought leaders and innovators in Osteosarcoma MIB Book: Osteosarcoma: From our Families to Yours RESEARCH: Annual MIB FACTOR Research Conference Funding multiple $100,000 and $50,000 grants annually for OS research MIB Testing & Research Directory The Osteosarcoma Project partner with Broad Institute of MIT and Harvard ... Kids are still dying with 40+ year old treatments. Help us MakeItBetter. https://www.mibagents.org​ Help support MIB Agents, Donate here https://give-usa.keela.co/embed/YAipuSaWxHPJP7RCJ SUBSCRIBE for all the Osteosarcoma Intel

    • 1 hr 3 min
    osTEAo - Coping with Cancer through Music

    osTEAo - Coping with Cancer through Music

    In this episode, OsteoWarriors Camille and Mia share songs that have resonated with them during their life with cancer. Find out why Fight Song is not their preferred anthem for AYA cancer patients and why hope can feel like a four letter word. Listen in as they break down lyrics, discuss why osteosarcoma is like a masochistic toxic ex, and examine how music can heal and help validate the feelings and emotions that AYA cancer patients deal with. You can also listen to these meaningful musical selections on a special Spotify playlist by copying and pasting the link here into your web browser, or scanning the QR code :

    https://open.spotify.com/playlist/6ARr8egX2vQ23Aql1ypSb5?si=0d1d2abf6da44cb5



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    What We Do at MIB Agents: PROGRAMS: End-of-Life MISSIONS Gamer Agents Agent Writers Prayer Agents Healing Hearts - Bereaved Parent and Sibling Support Ambassador Agents - Peer Support Warrior Mail Young Adult Survivorship Support Group EDUCATION for physicians, researchers and families: OsteoBites, weekly webinar & podcast with thought leaders and innovators in Osteosarcoma MIB Book: Osteosarcoma: From our Families to Yours RESEARCH: Annual MIB FACTOR Research Conference Funding multiple $100,000 and $50,000 grants annually for OS research MIB Testing & Research Directory The Osteosarcoma Project partner with Broad Institute of MIT and Harvard ... Kids are still dying with 40+ year old treatments. Help us MakeItBetter. https://www.mibagents.org​ Help support MIB Agents, Donate here https://give-usa.keela.co/embed/YAipuSaWxHPJP7RCJ SUBSCRIBE for all the Osteosarcoma Intel

    • 59 min
    OsteoBites Preguntas & Respuestas con Nino Rainusso, MD

    OsteoBites Preguntas & Respuestas con Nino Rainusso, MD

    OsteoBites Preguntas & Respuestas con Nino Rainusso, MD: Únase a nosotros para un episodio especial de OsteoBites en español. Nino Rainusso, MD del Texas Children's Hospital con preguntas de respuesta sobre el osteosarcoma de pacientes y cuidadores.



    El Dr. Nino Rainusso es miembro del equipo de tumores sólidos pediátricos y codirector del programa de cardiooncología del Texas Children's Hospital - Baylor College of Medicine. Su laboratorio se centra en comprender el papel de las células madre cancerosas (CSC) tanto en el desarrollo de tumores como en la resistencia a la quimioterapia en sarcomas pediátricos. Ha realizado varios estudios destinados a caracterizar las CSC en tumores óseos pediátricos. Han desarrollado varios modelos de xenoinjerto derivado de paciente (PDX) de osteosarcoma, sarcoma de Ewing, rabdomiosarcoma y sarcomas de tejidos blandos. Su laboratorio participa actualmente en un proyecto PDX multiinstitucional destinado a caracterizar y evaluar el impacto de nuevos enfoques terapéuticos en cánceres pediátricos que utilizan PDX.



    Dr. Nino Rainusso is a member of the Pediatric Solid Tumor Team and Co-Director of the Cardio-Oncology Program at Texas Children’s Hospital - Baylor College of Medicine. Their laboratory focuses on understanding the role of cancer stem cells (CSCs) in both tumor development and chemotherapy resistance in pediatric sarcomas. He has conducted several studies aimed to characterize CSCs in pediatric bone tumors. They have developed several patient-derived xenograft (PDX) models of osteosarcoma, Ewing sarcoma, rhabdomyosarcoma, and soft-tissue sarcomas. Their laboratory currently participates in a multi-institutional PDX project aimed to characterize and to evaluate the impact of novel therapeutic approaches in pediatric cancers using PDXs.

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    What We Do at MIB Agents: PROGRAMS: End-of-Life MISSIONS Gamer Agents Agent Writers Prayer Agents Healing Hearts - Bereaved Parent and Sibling Support Ambassador Agents - Peer Support Warrior Mail Young Adult Survivorship Support Group EDUCATION for physicians, researchers and families: OsteoBites, weekly webinar & podcast with thought leaders and innovators in Osteosarcoma MIB Book: Osteosarcoma: From our Families to Yours RESEARCH: Annual MIB FACTOR Research Conference Funding multiple $100,000 and $50,000 grants annually for OS research MIB Testing & Research Directory The Osteosarcoma Project partner with Broad Institute of MIT and Harvard ... Kids are still dying with 40+ year old treatments. Help us MakeItBetter. https://www.mibagents.org​ Help support MIB Agents, Donate here https://give-usa.keela.co/embed/YAipuSaWxHPJP7RCJ SUBSCRIBE for all the Osteosarcoma Intel

    • 55 min
    TCF-001 TRACK (Target Rare Cancer Knowledge): A Clinical Trial Studying Precision Medicine in Rare Cancers

    TCF-001 TRACK (Target Rare Cancer Knowledge): A Clinical Trial Studying Precision Medicine in Rare Cancers

    TCF-001 TRACK is a patient advocacy initiated, decentralized clinical trial enrolling patients with rare cancers and cancer of unknown primary. Patients can enroll remotely without a requirement to travel, and enrolled patients receive biomarker testing of tissue and blood at no cost, as well as treatment recommendations from a virtual molecular tumor board. This presentation will provide details on how TRACK works, and how it seeks to achieve its goals of providing patients with personalized, potentially actionable information while simultaneously generating critical research data.



    Jim Palma is the Executive Director of TargetCancer Foundation. Since joining TargetCancer Foundation in 2010, Jim has overseen its growth from a small start-up to a nationally recognized foundation supporting comprehensive rare cancer research programs and patient support services. Prior to joining TargetCancer Foundation, he spent eleven years at Fidelity Investments in Boston, MA. Jim is a member of the Board of Directors of the National Organization for Rare Disorders (NORD), and is a founding Co-Chair of the NORD Rare Cancers Coalition. In addition, Jim is a Steering Committee member at the GI Cancers Alliance and the Global Cholangiocarcinoma Alliance. Jim completed studies at the Institute for Nonprofit Management and Leadership at the Questrom School of Business at Boston University, and received his B.A. from Loyola University Maryland.



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    What We Do at MIB Agents: PROGRAMS: End-of-Life MISSIONS Gamer Agents Agent Writers Prayer Agents Healing Hearts - Bereaved Parent and Sibling Support Ambassador Agents - Peer Support Warrior Mail Young Adult Survivorship Support Group EDUCATION for physicians, researchers and families: OsteoBites, weekly webinar & podcast with thought leaders and innovators in Osteosarcoma MIB Book: Osteosarcoma: From our Families to Yours RESEARCH: Annual MIB FACTOR Research Conference Funding multiple $100,000 and $50,000 grants annually for OS research MIB Testing & Research Directory The Osteosarcoma Project partner with Broad Institute of MIT and Harvard ... Kids are still dying with 40+ year old treatments. Help us MakeItBetter. https://www.mibagents.org​ Help support MIB Agents, Donate here https://give-usa.keela.co/embed/YAipuSaWxHPJP7RCJ SUBSCRIBE for all the Osteosarcoma Intel

    • 59 min

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