This episode discusses six MMWR COVID-19 reports. The first one describes recommendations from the Advisory Committee on Immunization Practices for Johnson and Johnson's Janssen COVID-19 vaccine. Two reports detail how two new variants of the virus that causes COVID-19 were discovered in the United States. The fourth report underscores how proper resources and infection control measures can keep infection rates low among healthcare personnel. Another report found that the actual number of children in Mississippi with COVID-19 might have been much higher than the number of cases reported. The last report describes changes in rates of COVID-19 cases and deaths in counties with statewide mask mandates and counties where states allowed on-site dining at restaurants.