27 episodes

Barry Singer, MD, Director of The MS Center for Innovations in Care at Missouri Baptist Medical Center, interviews global expert guests about the latest treatments, innovations and tips for people living with multiple sclerosis.

MS Living Well: Key Info from Multiple Sclerosis Experts Barry Singer, MD

    • Health & Fitness
    • 4.9 • 77 Ratings

Barry Singer, MD, Director of The MS Center for Innovations in Care at Missouri Baptist Medical Center, interviews global expert guests about the latest treatments, innovations and tips for people living with multiple sclerosis.

    Personalized Medicine for MS

    Personalized Medicine for MS

    With over 20 options, what is the best multiple sclerosis treatment for me? Selecting an appropriate disease-modifying therapy (DMT) needs to consider your risk of worsening disability over time. Your age, sex and race can affect your prognosis and can influence the power of treatment chosen. Details about your early relapses and MRI activity are very important for treatment decisions.
    Treatment selection should also consider responsiveness to vaccines, family planning and other medical problems (another autoimmune disease or cancer). For each individual living with multiple sclerosis, balancing power of treatment against serious risks of treatment needs to be considered.  The future of personalizing care to better pick the right medication shared.
    Barry Singer MD, Director of The MS Center for Innovations in Care, interviews Celia Oreja-Guevara MD PhD, Vice Chair of Neurology & Head of the Multiple Sclerosis Center, University Hospital, San Carlos, Madrid, Spain & John Foley MD, Director, Rocky Mountain MS Clinic, Salt Lake City, Utah

    • 35 min
    Digital Health & MS

    Digital Health & MS

    Digital technology has transformed our lives. For people living with multiple sclerosis, electronic health opens a new world. Biosensors in our smartphones and wearable devices can monitor physical activity levels and sleep and may detect MS disease changes faster than that next neurologist appointment. New apps can help people with MS manage and track their disease including gaming to assess cognition.
    Digital health is becoming an indispensable part of in-office and virtual patient appointments. Privacy concerns with electronic healthcare addressed. Treatment decisions facing both doctors and patients are getting increasingly complex. New artificial intelligence technology may soon help personalize treatment and predict treatment response using a concept of a digital twin.
    Barry Singer MD, Director of The MS Center for Innovations in Care interviews:
    Jennifer Graves MD PhD is an Associate Professor at UC San Diego School of Medicine and serves as Director of the UC San Diego Neuroimmunology Research Program. Dr. Graves completed a fellowship in neuro-ophthalmology and residency in neurology at the University of Pennsylvania Perelman School of Medicine. She earned her medical degree and PhD in molecular biophysics from University of Texas Southwestern Medical School. She also holds a master's degree in epidemiology and biostatistics from UC San Francisco.
    Tjalf Ziemssen MD PhD is founder and director of the MS Center in Dresden, Germany where he did his neurology training. Professor Ziemssen is also Director of the Center of Clinical Neuroscience and the neuroimmunological lab at the Carl Gustav Carus University Hospital in Dresden. He completed his medical training and doctoral thesis at the University of Bochum. He also was a research fellow at the Max Planck Institute of Neurobiology.

    • 36 min
    Vision & Multiple Sclerosis

    Vision & Multiple Sclerosis

    Multiple sclerosis frequently causes visual impairment. 70% of people living with the disease can develop optic neuritis at some point and often the first sign of MS. The symptoms, medical evaluation, treatment and prognosis of optic neuritis are conveyed. Besides multiple sclerosis, other causes are discussed including MOG antibody-associated disease (MOGAD) and neuromyelitis (NMO).
    Double vision and shaky (or jumpy) vision are other concerning visual symptoms for people with MS. The reason for these eye movement abnormalities and detailed treatment options are covered. Experts share the latest advancements in vision research for those living with multiple sclerosis. Barry Singer MD, Director of The MS Center for Innovations in Care, interviews:
    Dr. Anneke van der Walt is an Associate Professor of Neurology at Monash University in Melbourne, Australia. She is the head of the MS and Neuro-ophthalmology Research Group. She completed her undergraduate work in South Africa and completed her neurology training and PhD at the University of Melbourne. She is also the Chief Operating Officer of MSBase Foundation.
    Dr. Tariq Bhatti is a neuro-ophthalmologist currently at Kaiser Permanente in Northern California. He completed his neuro-ophthalmology fellowship at Emory.  Dr. Bhatti was most recently a Professor of Ophthalmology and Neurology at Mayo Clinic and previously Chief of Neuro-ophthalmology at Duke University. 

    • 37 min
    Multiple Sclerosis Biomarkers including Blood Tests

    Multiple Sclerosis Biomarkers including Blood Tests

    Rapid recent advancements have led to blood tests (biomarkers) to track multiple sclerosis disease activity. A biomarker is something that can be measured to check normal functioning or the impact of a disease. Blood biomarkers are common in medicine to measure response to therapy such as measuring hemoglobin A1c levels for diabetic control and cholesterol levels for high cholesterol treatment.
    Injury to nerve cells (neurons) and other cells in the brain and spinal cord can be measured in the blood by checking levels of proteins such as neurofilament light chains (NfL) and glial fibrillary acid protein (GFAP). One panel of these blood markers helps identify people with multiple sclerosis with current active MRI scans. The future of MS biomarkers involves blood tests to diagnose multiple sclerosis, select the best treatment for an individual, and measure treatment response.
    Barry Singer MD, Director of The MS Center for Innovations in Care, interviews:
    Tanuja Chitnis MD, Professor of Neurology at Harvard Medical School, is the Director of both MGB Pediatric Multiple Sclerosis Center and Translational Neuroimmunology Research Center at Brigham and Women’s Hospital. She is also Co-Director of the Brigham Multiple Sclerosis Center at Brigham and Women’s Hospital. 

    • 21 min
    Aging and Multiple Sclerosis

    Aging and Multiple Sclerosis

    Our immune systems become less robust as we age. With an autoimmune disease such as multiple sclerosis, a weakened immune system can lead to less relapses and active MRI lesions. However, many people living with multiple sclerosis develop progressive disease with worsening physical and cognitive disability as they age. Strategies to live better with MS as one grows older are shared.
    The vast majority of treatments for multiple sclerosis have been studied in people 55 years of age or younger. However, 46% of people living with MS are older than age 55. New studies are answering important questions about MS treatment in older patients. At what age can treatment safely be stopped without risk of relapse or worsening disability? Safety concerns such as serious infections, cancer risk, and immunization responsiveness in older MS patients on immunosuppressive treatments are addressed.
    Barry Singer MD, director of The MS Center for Innovations in Care, interviews:
    Bianca Weinstock-Guttman MD, Professor of Neurology at the Jacobs School of Medicine & Biomedical Sciences in Buffalo, New York, and the Director of the Jacobs MS Center for Treatment and Research.
    John Corboy MD, Professor of Neurology at the University of Colorado Denver School of Medicine and Co-Director of the Rocky Mountain MS Center.

    • 32 min
    Diet & Multiple Sclerosis

    Diet & Multiple Sclerosis

    Trying to figure out the ideal diet for multiple sclerosis?  Two of the leading experts on diet and multiple sclerosis share our current understanding based on the latest research. Diets reviewed include intermittent fasting, Swank diet, Wahls protocol and Mediterranean diet.  The role of the gut organisms, called the microbiome, on immune health explained.
    In-depth information highlights how certain foods affect people living with multiple sclerosis. Specifically dairy, gluten, polyunsaturated fats, fruits, vegetables, salt, vitamins and supplements are covered.  Dr. Ellen Mowery and Dr. Ilana Katz Sand also discuss how they counsel their own MS patients on diet.
    Barry Singer MD, Director of The MS Center for Innovations in Care, interviews:
    Ellen Mowry MD is a Professor of Neurology and Epidemiology at Johns Hopkins University.  Dr. Mowry also co-directs the Johns Hopkins MS Precision Medicine Center of Excellence. Her research focuses on environmental factors that influence the risk and prognosis of multiple sclerosis.
    Ilana Katz Sand MD is an Associate Professor of Neurology at the Icahn School of Medicine at Mount Sinai and on staff at the Corinne Goldsmith Dickinson Center for MS in New York City. One of main areas of her research is the role of diet in MS.

    • 36 min

Customer Reviews

4.9 out of 5
77 Ratings

77 Ratings

Francis#7 ,

Thank you

Dr Singer has helped my Vennisa achieve two clear MRI’s in the last year!
I’m a podcast fan and enjoy this one for sure.
Well done all around!

68KAnderson ,

MS patients and families have to listen to this podcast

I have learned so much about my MS from Dr. Singer’s podcasts!! I have been a patient of his since my diagnosis and you only have so much time at your appointments. . . I feel so much more knowledgeable about my disease!! Thank you all so much!!

1279926 ,

Great and informative podcast. Highly recommend

Great info for anyone with MS or anyone who knows someone with MS. Very helpful, highly recommend. Dr. Singer discusses interesting and helpful strategies with MS experts on how to maximize the quality of life and attain your goals, covers new research and patterning with your neurologist.

Great info from experts on handling Fatigue, Cognition and other symptoms of MS. Highly recommend!

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