Osteomyelitis: Achieving Antibiotic Penetration On Medical Grounds

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Dr. Adam Bressler is an infectious disease specialist affiliated with Emory Hillandale Hospital and Emory Decatur Hospital. He will be joining us to discuss the role of antibiotic-resistance and other complications in current treatment regimens for osteomyelitis, developments in novel glycopeptide antibiotic treatments for Gram-positive and antibiotic-resistant osteomyelitis, and the multidisciplinary approach to the diagnosis and treatment of osteomyelitis. 

(00:22) CME/CE information
(01:57) What is osteomyelitis and why is it tough to treat
(02:53) Role of antibiotic or antimicrobial resistance
(03:37) Challenges of bone tissue
(04:45) Role of biofilms in osteomyelitis
(06:30) First line treatments often fail
(07:28) New antibiotics showing promise
(09:15) Need for guidelines for osteomyelitis treatment
(10:35) Glycopeptide antibiotics
(11:08) Glycopeptide antibiotic mechanisms
(11:55) Telavancin Observational Use Registry (TOUR) study
(13:03) TOUR methods
(14:04) TOUR results
(16:46) Infusion centers and pumps
(17:58) TOUR demographics
(20:20) Immunocompromised patients and other risk factors
(24:18) Multidisciplinary approach