54 min

Ep.35 - Jon Jones & The Long Term Metabolite for Turinabol Anti-Doping Science Podcast

    • Sports

Earlier this week it was announced that Jon Jones’s urine produced an Adverse Analytical Finding (AAF) for a long-term metabolite for the Anabolic Androgenic Steroid (AAS) Chlorodehydromethyltestosterone (DHCMT) – which is known by it’s trade name Oral-Turinabol. This is the 2nd time this long-term metabolite has been discovered inside Jon Jones urine. This podcast covers a detailed discussion on Jon Jones’s previous anti-doping rule violation for Clomiphene, his 2nd antidoping rule violation for the M3 metabolite and a discussion of the reappearance of this metabolite in his urine. I also discuss the research that has been conducted so far on the long-term metabolite (M3 metabolite) of Turinabol. Links to all reference material is below:

Article on Jon Jones Fighting History: https://mmajunkie.com/2018/12/ufc-232-preview-jon-jones-career-statistics-facts

Article on Atypical Finding announced in December 2018: https://mmajunkie.com/2018/12/jon-jones-drug-test-atypical-result-ufc-232-moved-to-los-angeles-gustafsson-dana-white

Article on Jones’s 1st AAF for Clomiphene: http://www.espn.com/mma/story/_/id/25608180/jon-jones-long-winding-road-ufc-232

Article on Clomiphene https://anabolic.org/clomid-clomiphene-citrate/
USADA High Risk List of Supplements & Supplement 411: https://www.usada.org/substances/supplement-411/

USADA Arbitration Report on 2nd AAF for M3 Metabolite for Turinabol: https://ufc.usada.org/wp-content/uploads/Final-Redacted-Award-Jones-and-USADA.pdf

Discovery of the M3 metabolite in 2012 by Sobolevsky & Rodchenkov: https://www.ncbi.nlm.nih.gov/pubmed/22142641

Critique of Sobolevsky & Rodchenkov’s research: https://www.researchgate.net/publication/305489931_Novel_metabolites_of_turinabol_WADA_moving_toward_illusions

Synthesis of the M3 metabolite in 2018 (also discussing the extension in detection from the long term metabolite): https://pubs.rsc.org/en/content/articlelanding/2018/ob/c8ob00122g#!divAbstract

Confirmation of the M3 metabolite in 2018: https://www.ncbi.nlm.nih.gov/pubmed/29570240

Earlier this week it was announced that Jon Jones’s urine produced an Adverse Analytical Finding (AAF) for a long-term metabolite for the Anabolic Androgenic Steroid (AAS) Chlorodehydromethyltestosterone (DHCMT) – which is known by it’s trade name Oral-Turinabol. This is the 2nd time this long-term metabolite has been discovered inside Jon Jones urine. This podcast covers a detailed discussion on Jon Jones’s previous anti-doping rule violation for Clomiphene, his 2nd antidoping rule violation for the M3 metabolite and a discussion of the reappearance of this metabolite in his urine. I also discuss the research that has been conducted so far on the long-term metabolite (M3 metabolite) of Turinabol. Links to all reference material is below:

Article on Jon Jones Fighting History: https://mmajunkie.com/2018/12/ufc-232-preview-jon-jones-career-statistics-facts

Article on Atypical Finding announced in December 2018: https://mmajunkie.com/2018/12/jon-jones-drug-test-atypical-result-ufc-232-moved-to-los-angeles-gustafsson-dana-white

Article on Jones’s 1st AAF for Clomiphene: http://www.espn.com/mma/story/_/id/25608180/jon-jones-long-winding-road-ufc-232

Article on Clomiphene https://anabolic.org/clomid-clomiphene-citrate/
USADA High Risk List of Supplements & Supplement 411: https://www.usada.org/substances/supplement-411/

USADA Arbitration Report on 2nd AAF for M3 Metabolite for Turinabol: https://ufc.usada.org/wp-content/uploads/Final-Redacted-Award-Jones-and-USADA.pdf

Discovery of the M3 metabolite in 2012 by Sobolevsky & Rodchenkov: https://www.ncbi.nlm.nih.gov/pubmed/22142641

Critique of Sobolevsky & Rodchenkov’s research: https://www.researchgate.net/publication/305489931_Novel_metabolites_of_turinabol_WADA_moving_toward_illusions

Synthesis of the M3 metabolite in 2018 (also discussing the extension in detection from the long term metabolite): https://pubs.rsc.org/en/content/articlelanding/2018/ob/c8ob00122g#!divAbstract

Confirmation of the M3 metabolite in 2018: https://www.ncbi.nlm.nih.gov/pubmed/29570240

54 min

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