Pharmacology is one of the most challenge topics you will encounter as a healthcare professional, but it can be the most rewarding with a good understanding. Whether you are preparing to be a nurse, physician, physician assistant, pharmacist, dentist, nurse practitioner, pharmacy technician, pharmacologist, or other healthcare professional, this podcast will help you better understand pharmacology. In addition to giving you the basics like mechanism of action, side effects, drug interactions, etc., you will also be exposed to how medications actually impact patients in real life. In the Real Life Pharmacology podcast, Eric Christianson, PharmD shares his real world experiences about how a medication's mechanism of action, pharmacokinetics, adverse effects, and drug interactions can actually impact patients in both a positive and a potentially negative way. Eric Christianson PharmD is the author of the popular clinical pharmacy blog Meded101.com. People who are passionate about nursing, medicine, or pharmacy will find this podcast beneficial in helping them prepare for passing exams. This podcast is for educational purposes only and is not medical advice or intended to be a substitute for medical advice. Please seek advice from your pharmacist or primary care provider if you have questions about medications that you are taking.
On this episode of the Real Life Pharmacology Podcast, I discuss escitalopram pharmacology.
Escitalopram is an SSRI and can be used to manage depression, anxiety, OCD, PTSD, and other psychiatric disorders.
If you consider fluoxetine the most activation SSRI and paroxetine the most sedating, escitalopram probably falls somewhere in the middle.
Sexual dysfunction is a potential adverse effect with escitalopram. I discuss it further on this episode.
On this episode of the Real Life Pharmacology Podcast, I cover ziprasidone pharmacology.
Ziprasidone has dopamine blocking activity and is classified as a second generation antipsychotic.
Ziprasidone tends to have lower metabolic syndrome risks compared to other antipsychotics like clozapine and olanzapine.
QTc prolongation is a significant risk with ziprasidone and be aware of drug interactions and electrolyte imbalances that may increase this risk.
On this episode, I discuss tiotropium pharmacology. In addition, I cover adverse effects, administration pearls, and drug interactions.
Tiotropium blocks acetylcholine from binding the M3 receptor in the lungs. This leads to a relaxation of the bronchial smooth muscle.
Because tiotropium has anticholinergic activity, there is a potential for anticholinergic adverse effects like constipation, urinary retention, and dry mouth.
The tiotropium Handihaler can be confusing to patients. I discuss medication misadventures in this podcast episode.
On this episode, I discuss palivizumab pharmacology and how it is used in pediatric patients.
Palivizumab is a monoclonal antibody that is used to prevent RSV infections in pediatric patients.
Palivizumab is an IM injection that is dosed by weight. Learn more on this podcast episode.
RSV can be devastating in pediatric patients under the age of two. Palivizumab can be used in select populations to help prevent the infection.
Injection and skin reactions are possible with the use of palivizumab.
Varenicline is a partial nicotine agonist that can be used to help patients quit smoking.
The two most common adverse effects that I have seen in clinical practice with varenicline are GI upset and insomnia/vivid dreams.
GI upset with varenicline can be reduced by giving the drug with food and a full glass of water. A dose reduction may also be considered.
Patients should identify a goal stop date for smoking cessation prior to begininng the use of varenicline.
Diphenhydramine (Benadryl) Pharmacology
Diphenhydramine is a first generation antihistamine that is highly anticholinergic.
When using medications like diphenhydramine, be sure to watch for side effects like dry eyes, dry mouth, constipation, urinary retention, and CNS changes.
Sedation is a primary effect of diphenhydramine. It can be advantageous in certain situations, and detrimental in others.
Drugs like donepezil, memantine, laxatives, tamsulosin, and artificial tears can be indicators of anticholinergic side effects from diphenhydramine.
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Amazing, simply amazing
This is just what every pharmacy students needs!
Short and to the point
Amazing I recommend to all my pharmacy students they love it I wait and wait for the next podcast thank you so much for providing this great information (spoken message)
I am so glad I found this podcast. I have already picked up so much clinical pearls. I have shared this podcast with my colleagues who also appreciate the great content of each podcast. Eric also has great audio books available. I just got the drug interaction audiobook which is superb.