Pharmacology is one of the most challenge topics you will encounter as a healthcare professional, but it can be the most rewarding with a good understanding. Whether you are preparing to be a nurse, physician, physician assistant, pharmacist, dentist, nurse practitioner, pharmacy technician, pharmacologist, or other healthcare professional, this podcast will help you better understand pharmacology. In addition to giving you the basics like mechanism of action, side effects, drug interactions, etc., you will also be exposed to how medications actually impact patients in real life. In the Real Life Pharmacology podcast, Eric Christianson, PharmD shares his real world experiences about how a medication's mechanism of action, pharmacokinetics, adverse effects, and drug interactions can actually impact patients in both a positive and a potentially negative way. Eric Christianson PharmD is the author of the popular clinical pharmacy blog Meded101.com. People who are passionate about nursing, medicine, or pharmacy will find this podcast beneficial in helping them prepare for passing exams. This podcast is for educational purposes only and is not medical advice or intended to be a substitute for medical advice. Please seek advice from your pharmacist or primary care provider if you have questions about medications that you are taking.
On this episode, I discuss atenolol pharmacology, adverse effects, pharmacokinetics, and drug interactions.
Atenolol is primarily cleared by the kidney which should tell you that we need to pay attention to dose adjustments as renal function declines.
Atenolol is a beta-1 selective agent that is NOT a preferred beta-blocker in HFrEF.
Pulse and blood pressure monitoring is essential with any beta-blocker like atenolol.
On this episode, I discuss hydromorphone pharmacology, adverse effect, and drug interactions.
I discuss the pharmacokinetics of hydromorphone and also discuss the relative potency compared to other opioids.
Hydromorphone drug interactions are mostly additive effects. Drugs that cause sedation or constipation can have additive effects on hydromorphone.
Be extremely careful with hydromorphone dosage forms. There are numerous different concentrations and strengths. I discuss this in this episode.
On this episode, I discuss duloxetine pharmacology, adverse effects, and common drug interactions.
Duloxetine is an SNRI that is used for depression, anxiety, and various pain syndromes like neuropathy and fibromyalgia.
Duloxetine can inhibit CYP2D6 which can lead to higher concentrations of clozapine and propranolol and lower activity of tamoxifen.
CYP1A2 inhibitors like ciprofloxacin can raise concentrations of duloxetine leading to an increased potential for adverse effects.
Lasmiditan (Reyvow) is an agent that is utilized for acute migraine treatment. It works slightly differently than triptans which I discuss on this episode.
Lasmiditan is a relatively new agent and cost will often limit its use at this time.
Rosuvastatin and sulfasalazine are two common medications that may have concentrations increase when lasmiditan is used. I discuss this in detail on this episode.
Lasmiditan is an oral tablet that is only recommended to give once per day which differs from commonly used triptans where the dose can be repeated.
On this episode, I discuss sumatriptan pharmacology, adverse effects, drug interactions and more.
Dosage forms can provide different methods of drug delivery and I talk about many different sumatriptan dosage forms in this episode.
Cardiovascular risks need to be assessed when using a drug like sumatriptan. I discuss this in greater detail in the podcast.
Sumatriptan has serotonergic activity and we need to assess the risk of serotonin syndrome in our patients.
On this episode of the Real Life Pharmacology Podcast, I discuss bumetanide pharmacology, adverse effects, and drug interactions.
Bumetanide is a loop diuretic and it is critical to monitor renal function and electrolytes with this medication.
Ototoxicity is a rare adverse effect that is dose-dependent and can be worsened by aminoglycosides.
It is critical to look for drugs that can worsen edema when using bumetanide to ensure that we avoid the prescribing cascade.
Best podcast in healthcare
This podcast is so informative. Is a great review on pharmacology. I listen to it on my way to work, at home and really every time I have time.
Concise and Informative
Thank you for your podcast and other resources. Very useful! Keep up the great work!
I’m newly licensed FNP, I find this material very useful. Thank you for what you do - Chinie michelle fnp-c