S6 E2: Don't Eat Those Brains! The Story of Chronic Wasting Disease Cause of Death - 100 Seconds to Midnight

    • Life Sciences

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Who’s Who Outside of the Zoo has begun!
Hello and welcome to Cause of Death – 100 Seconds to Midnight. I’m your host, Jackie Moranty.
Here we are in Season Six. This season is dedicated to wildlife disease and conservation.
I’ve been trying to keep seasons at about 8 episodes, but this one may run a little longer. There’s a lot to talk about when it comes to wildlife disease and conservation and the way that they come together.
I’ll be introducing some things that we haven’t talked about previously. Many of the diseases of wildlife are obscure and though the symptoms may sound like a virus or a bacterial infection, they could be something completely different.
This brings us to today’s episode.
Chronic Wasting Disease in cervids. It’s caused by an organism that we haven’t talked about before. It’s a prion.
I’m the first to admit that I’m terrified of prions. They’re unpredictable, they’re incurable and they’re fatal. The worst thing about them is that they take years to manifest, so you don’t know you have one until it’s too late to do much about it.
Sound terrifying? Keep listening!
I’m going to be doing a special 100 Seconds to Midnight episode in Season 7. I’d like those of you who had experiences growing up during the Cold War to talk about those experiences.
If you’d like to be a guest on the show, I can arrange that. If you’d rather just write your stories and send them in, that’s fine, too. I can read them.
These stories are important, and they need to be heard. Please participate if you can.
You can reach me on the website at www.causeofdeath100secs.net or you can email me at Jackie@causeofdeath100secs.net.
My Link Tree can be found at: https://linktr.ee/CauseofDeathpod
CWD Show Notes:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874178/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877840/
https://www.cdc.gov/prions/cwd/transmission.html#:~:text=Scientists%20believe%20CWD%20proteins%20(prions,of%20soil%2C%20food%20or%20water.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173489/#:~:text=Finally%2C%20we%20discuss%20prions.,properties%20of%20size%20and%20infectiousness.
https://www.hopkinsmedicine.org/health/conditions-and-diseases/prion-diseases
https://www.hopkinsmedicine.org/health/conditions-and-diseases/prion-diseases
https://www.scientificamerican.com/article/what-is-a-prion-specifica/
https://www.doi.gov/ocl/chronic-wasting-disease
https://www.nps.gov/articles/cwd.htm
https://www.dfw.state.or.us/wildlife/health_program/chronic_wasting/
https://wildlifemanagement.institute/outdoor-news-bulletin/december-2017/what-hunters-can-do-stop-chronic-wasting-disease
https://www.scientificamerican.com/article/what-is-a-prion-specifica/
https://www.deerfriendly.com/deer-disease/chronic-wasting-disease/possible-origins-of-chronic-wasting-disease
https://cwd-info.org/cwd-overview/
https://cwd-info.org/timeline/
https://www.aphis.usda.gov/aphis/ourfocus/wildlifedamage/programs/nwrc/sa_spotlight/accomplishments_chronic_wasting_disease
https://wildlife.tamu.edu/cwdhistory/
https://www.cdc.gov/prions/cwd/occurrence.html
https://www.sciencedirect.com/science/article/pii/S0925443906002201
https://www.frontiersin.org/articles/10.3389/fviro.2023.1055487/full
https://journals.asm.org/doi/10.1128/mBio.01091-19
https://www.usgs.gov/faqs/what-causes-chronic-wasting-disease
https://cwd-info.org/recommendations-for-hunters/
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/733407/DEFRA_QRA_TSE_in_cervids_June2018_v1.pdf
https://scholar.google.com/citations?user=G5JCz8MAAAAJ&hl=en
https://www.kunc.org/science/2019-04-24/bent-out-of-shape-part-3-a-complicated-turn-of-events
https://pagosadailypost.com/wp-content/uploads/2021/01/18-Prion-Research-Letter.pdf
https://www.drovers.com/news/burning-might-help-prevent-cwd-transmission
https://arssymposium.org/wp-content/uploads/2014/06/2013_USDA_ARS_V-Hoover.pdf
https://journals.plos.org/ploson

Who’s Who Outside of the Zoo has begun!
Hello and welcome to Cause of Death – 100 Seconds to Midnight. I’m your host, Jackie Moranty.
Here we are in Season Six. This season is dedicated to wildlife disease and conservation.
I’ve been trying to keep seasons at about 8 episodes, but this one may run a little longer. There’s a lot to talk about when it comes to wildlife disease and conservation and the way that they come together.
I’ll be introducing some things that we haven’t talked about previously. Many of the diseases of wildlife are obscure and though the symptoms may sound like a virus or a bacterial infection, they could be something completely different.
This brings us to today’s episode.
Chronic Wasting Disease in cervids. It’s caused by an organism that we haven’t talked about before. It’s a prion.
I’m the first to admit that I’m terrified of prions. They’re unpredictable, they’re incurable and they’re fatal. The worst thing about them is that they take years to manifest, so you don’t know you have one until it’s too late to do much about it.
Sound terrifying? Keep listening!
I’m going to be doing a special 100 Seconds to Midnight episode in Season 7. I’d like those of you who had experiences growing up during the Cold War to talk about those experiences.
If you’d like to be a guest on the show, I can arrange that. If you’d rather just write your stories and send them in, that’s fine, too. I can read them.
These stories are important, and they need to be heard. Please participate if you can.
You can reach me on the website at www.causeofdeath100secs.net or you can email me at Jackie@causeofdeath100secs.net.
My Link Tree can be found at: https://linktr.ee/CauseofDeathpod
CWD Show Notes:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874178/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877840/
https://www.cdc.gov/prions/cwd/transmission.html#:~:text=Scientists%20believe%20CWD%20proteins%20(prions,of%20soil%2C%20food%20or%20water.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173489/#:~:text=Finally%2C%20we%20discuss%20prions.,properties%20of%20size%20and%20infectiousness.
https://www.hopkinsmedicine.org/health/conditions-and-diseases/prion-diseases
https://www.hopkinsmedicine.org/health/conditions-and-diseases/prion-diseases
https://www.scientificamerican.com/article/what-is-a-prion-specifica/
https://www.doi.gov/ocl/chronic-wasting-disease
https://www.nps.gov/articles/cwd.htm
https://www.dfw.state.or.us/wildlife/health_program/chronic_wasting/
https://wildlifemanagement.institute/outdoor-news-bulletin/december-2017/what-hunters-can-do-stop-chronic-wasting-disease
https://www.scientificamerican.com/article/what-is-a-prion-specifica/
https://www.deerfriendly.com/deer-disease/chronic-wasting-disease/possible-origins-of-chronic-wasting-disease
https://cwd-info.org/cwd-overview/
https://cwd-info.org/timeline/
https://www.aphis.usda.gov/aphis/ourfocus/wildlifedamage/programs/nwrc/sa_spotlight/accomplishments_chronic_wasting_disease
https://wildlife.tamu.edu/cwdhistory/
https://www.cdc.gov/prions/cwd/occurrence.html
https://www.sciencedirect.com/science/article/pii/S0925443906002201
https://www.frontiersin.org/articles/10.3389/fviro.2023.1055487/full
https://journals.asm.org/doi/10.1128/mBio.01091-19
https://www.usgs.gov/faqs/what-causes-chronic-wasting-disease
https://cwd-info.org/recommendations-for-hunters/
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/733407/DEFRA_QRA_TSE_in_cervids_June2018_v1.pdf
https://scholar.google.com/citations?user=G5JCz8MAAAAJ&hl=en
https://www.kunc.org/science/2019-04-24/bent-out-of-shape-part-3-a-complicated-turn-of-events
https://pagosadailypost.com/wp-content/uploads/2021/01/18-Prion-Research-Letter.pdf
https://www.drovers.com/news/burning-might-help-prevent-cwd-transmission
https://arssymposium.org/wp-content/uploads/2014/06/2013_USDA_ARS_V-Hoover.pdf
https://journals.plos.org/ploson