Stem Cell Channel (Audio‪)‬ UCTV

Elena Ezhkova, Ph.D., discusses the role of Merkel cells in touch sensation and their connection to nerves. She shares research on skin cancer formation, focusing on the PRC1 complex's impact on gene expression. Ezhkova also investigates epithelial-to-mesenchymal transition (EMT), finding it contributes to cancer spread. Ezhkova offers insights for potential cancer treatments. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38335]

Amander Clark, Ph.D., delves into crafting artificial ovaries for fertility and aging research. She stresses the importance of diversity in stem cell studies to ensure comprehensive findings. By assembling ovarian models from various genetic backgrounds, her team aims for inclusive representation in biomedical research, potentially offering insights into reproductive health and disease. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38334]

Hanna Mikkola, M.D., Ph.D., shares her work in hematopoietic stem cells (HSCs) and their complex renewal process. Her research aims to unravel these cells' behavior in mice and humans, offering potential insights for future medical advancements. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39258]

Mathew Blurton-Jones presents CRISPR-based interventions for a rare brain disorder in mice by substituting defective brain cells with healthy ones. He details experiments demonstrating the efficacy of corrected cells in mitigating brain pathologies. Blurton-Jones emphasizes the need for cautious translation to human trials, advocating gradual cell replacement to preempt potential adverse effects. Additionally, he delves into the implications of microglia in Alzheimer's disease progression and explores potential interconnections among various neurodegenerative conditions. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38333]

Anna Beaudin, Ph.D., delves into the intricacies of how prenatal inflammation impacts the immune system's blueprint, shaping its long-term function. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39257]

CIRM-funded Alpha Stem Cell Clinics are a network of California medical centers that specialize in delivering stem cell clinical trials to patients. In this fascinating panel, clinic directors discuss advanced treatments, therapies like gene editing, and sharing knowledge and creating networks across the country for better patient care.

Featuring:

Geoffrey Lomax, Dr.PH
California Institute for Regenerative Medicine

Esther and Andrew Schorr
Patient Advocates

Sandra Dillon
Cancer Survivor and Stem Cell Champion

Catriona Jamieson, M.D., Ph.D.
UC San Diego

Mehrdad Abedi, M.D.
UC Davis

Daniela A. Bota, M.D., Ph.D.
UC Irvine

Sheila Chari, Ph.D.
Cell Press

Leo D. Wang, M.D., Ph.D.
City of Hope National Medical Center

Mark Walters, M.D.
University of California, San Francisco

Thomas Buchanan, M.D.
University of Southern California

Michael Lewis, M.D.
Cedars Sinai

Noah Federman, M.D.
UCLA Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39070]