A podcast capturing the stories of scientific brilliance. For a long time, science podcasts have been about DrySci (“Dry science”). It relates topics at too high a level or too generalistic. We aim to change that by bringing the stories of the people, their motivations and specifically the struggles and glories of stories past that will seek to reinvigorate, rejuvenate and respect the minds before the results. This podcast is an effort to soothe that incurable itch in your brain. We ask questions that you always to ask the experts but always had to polite and keep it to the science.
What's a trip really like?
If you’ve listened to the PsychedRx series, or ever contemplated experiencing psychedelics, you’ve probably asked yourself what a trip is really like. Well, I’d very much like to tell you what it’s like, but it’s much like trying to describe an exact shade of purple velvet. It’s deep, rich, bright, dark, it changes as the light shifts. When you touch it, everything changes. It’s different in the morning than it is at night. It’s simultaneously warm and cool, comforting and challenging, but it’s something you can’t fully appreciate or describe without seeing it in person.
For additional exploration and examination, we’ve engaged a first-rate scientist and psychonaut of sorts to help us understand, as best we can…
With that, we’d like to thank Juan for sharing his experiences and perspectives with us. We’d also like to thank all of our participants for their time, dedication, talent, and insights. Finally, we’d like to thank each of you for taking this journey with us.
Peeling the Onion: Nobel Prize 2021 announcement in Medicine & Physiology
October 4, 2021 marked the announcement of the Nobel Prize in Physiology and Medicine to Dr. David Julius and Dr. Ardem Parpoutian.
This episode goes behind the relevance of their findings and why it is such an important moment for a field that brings together biology, physics, chemistry and medicine.
Key Reviews to dig into:
TRP channels: Click herePiezo channels: Click here
Building a perfect life (or Not) - #PsychedeRx Bonus Episode No. 2
This is JoJo, your friend and co-host of SKRAPS.
I grew up around construction. Tradesmen and experts at the crafts of building and repairing homes were omnipresent in my childhood. From a very young age, I knew more about framing than I did about Barbie dolls. I was comfortable in the world of power tools and knew the importance of “measure twice, cut once” before I knew my multiplication tables.
Any contractor worth his or her salt will tell you that a sound foundation is the most important thing you need in any structure. A compromised foundation will compromise everything that you build on top.
People have foundations, too. Our education, our family, our upbringing, our experiences and support systems all contribute to building our own foundations. Even with a solid foundation, it can become cracked when the earth below us shifts or when external forces push us too hard. Theses cracks and shifts are sometimes the cause of immense pain - pain so deep that no amount of paint and putty and window dressings can fix the real problem. Oh, we can try and DIY our way out of it - watch a few episodes of “Flip or Flop”, dress up our homes and ourselves, but the cracks remain. And the cracks eventually get bigger.
Sometimes, not often, but sometimes, we can find the tools to fix the cracks and bring the foundation back to a sound a solid state. But all too often, we lack the proper tools and skills and the pressures are just too much. The foundation finally gives way and our structures come tumbling down.
Why am I speaking in construction metaphors? To demonstrate to you that our tool kit is inadequate. That the chaos and destruction of unaddressed mental health issues are ruinous and that they need a shopping spree at Home Depot. If we can expand our mental health tool kit to include tools like psychedelic medicines, maybe we can salvage a few more homes.
Thank you Lindsay for sharing your story of your journey with Justin and for inspiring us to support meaningful research that can give us more, better, and different tools.
SKRAPS NeuroTech NewsHour: Sep 21
Join us to listen to the bi-weekly news round up on all things #NeuroTech and #BioelectronicMedicine.
This week we talk about academic news with Cleveland NeuroTech Entrepreneurs workshop, UConn hiring spree in Engineering with focus on NeuroTech.
On industry side, we cover Rune Labs, Tivic Health, Opinions on Nyxoah and their FDA breakthrough designation, Axonics/ Medtronic Patent Rulings.
Plus we are joined by Victor Pikov of Medipace & TRI, Khalid Ishaque of Bioinduction for the new around.
Join us for our biweekly Newshour on Clubhouse. We post details on LinkedIn and Twitter.
Psychedelics: When is it a bad idea? - #PsychedeRx Bonus Episode No. 1
Over the ten episodes in this series, it’s clear that we are enthusiastic about the future of psychedelic medicines. There are so many potential applications for responsible, physician-assisted therapies that it almost seems as though psychedelics are a silver bullet, or a little black dress - perfect for any occasion and applicable to myriad diseases and conditions.
Not to contradict ourselves, but there are definitely situations in which psychedelic medicines are not only ineffective, but ill-advised or flat out a bad idea. We hope to provide responsible and balanced information to our listeners and believe that we have done so. The PTSD episode, you heard from the leaders of Heroic Hearts and Heroic Hearts UK about their non-negotiable exclusion criteria. But the same way you heard emotional personal stories about their success, we thought it imperative to share with you a story about why not everyone and not everything can be helped with psychedelic medicines and why responsible use is the only possible solution.
We give our special thanks to Dr. Erika Ross for sharing the story that changed her life. This one is for Kreg.
#PsychedeRx Episode 10: Investing in New Frontiers of the Psychedelic Renaissance
New molecules, new IP, new opportunities. How can investors be induced to support the massive, but necessary funds required to support the important and carefully regulated research necessary to bring psychedelic therapies to market. Not to be crass, but if something isn’t going to bring a profit, it’s unlikely to receive much funding, regardless of how much good it might do, certainly not enough to cover the massive costs of bringing a disruptive therapy to market. Companies like Cybin and Bright Minds Bio are looking at modifications to create new IP, improved efficacy, and new delivery mechanisms.
With investment validations now taken care of, we need to address issues around delivery of care. Are we prepared to shift to a model of care that moves from weekly one-hour sessions to intensive, multi-hour sessions that require new paradigms that have never been tried? Before you answer, let us ask you another question: with between 11 and 20 out of every 100 US Veterans suffering from PTSD, how can we afford not to try?
Clara Burtenshaw, co-founder of Neo Kuma Ventures created the first European Fund dedicated to psychedelics shared with us her motivations, both professional and personal, for focusing on this space. We visited with Wavepaths CEO Mendel Kaelen about their founding principles and objectives; we explore Kernel’s entre into the psychedelic research space, and we revisit Doug Drysdale, CEO of Cybin. These are the folks to watch for the future of psychedelic medicines and the healthcare revolution that is coming your way.
It has been our pleasure to bring to you this series - this passion project to understand and share the opportunities, challenges, history, and future of psychedelic medicine.
Arun and JoJo
This series is only possible because of the generosity of spirit, time, resources, and dreams of our guests and contributors. A special thanks to Sharena Rice for her excellent research. Romeo Racz for technical support. Last but not the least, the unsung hero of our podcast series is our sound engineer, Mr. Swaminathan ThiruGnanaSambandam who did the mixing and mastering of audio.
The Real Deal
JoJo and Arun are great neurotechnology communicators— partly because they have been in the field for a long time.
Skraps is not pop science, it is the real deal. Approachable and understandable for citizen scientists/non-experts.
These are deeper stories of the people behind the innovations.