421 episodes

Talking Biotech is a weekly podcast that uncovers the stories, ideas and research of people at the frontier of biology and engineering.

Each episode explores how science and technology will transform agriculture, protect the environment, and feed 10 billion people by 2050.

Interviews are led by Dr. Kevin Folta, a professor of molecular biology and genomics.

Talking Biotech with Dr. Kevin Folta Colabra

    • Science
    • 4.8 • 266 Ratings

Talking Biotech is a weekly podcast that uncovers the stories, ideas and research of people at the frontier of biology and engineering.

Each episode explores how science and technology will transform agriculture, protect the environment, and feed 10 billion people by 2050.

Interviews are led by Dr. Kevin Folta, a professor of molecular biology and genomics.

    Temporary Hiatus, Changes Coming!

    Temporary Hiatus, Changes Coming!

    After 8.5 years of weekly podcasts I'm going to take a 5 week break and plan new episodes for 2024.  I'm going through a medical glitch that has me unable to do my normal work. On top of this we're going to switch to an audio plus video format to find a wider audience. So check back in 2024 for the next episode. Have a great rest of 2023, thank you for listening, and looking forward to better times. 

    • 7 min
    A Novel RNAi Approach to Crop Protection - Todd Hauser

    A Novel RNAi Approach to Crop Protection - Todd Hauser

    Even under the best conditions, crops need our assistance to survive the numerous threats that limit production. Classically, synthetic and natural compounds have been used to control insects, fungi and weeds, sometimes with negative collateral effects or fostering resistance of genetically tolerant genotypes. Todd Hauser from Trillium Ag describes his company's novel RNAi approach.  RNAi can be used to target specific insect species, and his company's design and particle-based technology appears to offer safety, effectiveness, and specificity. We discuss the use of RNAi and how it may be a key point of crop protection strategies, along with its inherent challenges.  

    • 35 min
    Drugs from the Rainforest - Lisa Conte

    Drugs from the Rainforest - Lisa Conte

    There is tremendous variation in the plant kingdom, as plants have adapted to many ecological niches with discrete challenges. Part of adaptation is production of novel secondary metabolites, compounds not required for central metabolism that serve a role in the plant, such as defense or attraction of pollinators. The rainforest is replete with unusual plants and their resident metabolites. Indigenous peoples have identified therapeutic qualities of specific plants. How can this knowledge be transferred to aid those suffering beyond the rainforest? Lisa Conte is the CEO, President and Founder of Jaguar Health, a subsidiary of Napo Pharmaceuticals.  We discuss process of working with indigenous peoples to learn from their findings, then test and validate them in ways to identify novel mechanisms of action for use in modern medicine. 

    • 42 min
    Proposed Gene Editing Changes in the EU -Dr. Emma Kovak

    Proposed Gene Editing Changes in the EU -Dr. Emma Kovak

    Gene editing is a powerful and specific technique that allows customized changes to DNA. Because there are no additional sequences transferred, and alternations match what could happen naturally over time, the technology is considered less invasive and less prone to regulatory oversight. That's true in the USA, Canada, China and other nations. However, the European Court of Justice determined that these techniques should be regulated in a manner identical to transgenics, where the EU has not approved such innovations in over two decades. EU scientists see how the EU is falling behind and after long may never catch up. The rejection of technology leads to a tremendous economic loss. Dr. Emma Kovak of the Breakthrough Institute discusses the current regulations, the proposed changes, and the dynamics of opposition to a good technology that could have profoundly positive impacts for people and the planet. 

    • 49 min
    "On Disinformation" Critical Conversations in the Post-Truth Era- Dr. Lee McIntyre

    "On Disinformation" Critical Conversations in the Post-Truth Era- Dr. Lee McIntyre

    Information has been weaponized, and the ability to create false information to achieve an ideological goal has never been more easy. Political polarization, science denial, and a shining, effective conduit of dissemination (the internet) allows anyone with an agenda to recruit the like minded, and produce compelling media to reinforce bankrupt ideas. Where did information warfare originate, what are its effects, and how do we fix it?  This week's podcast discusses the book, On Disinformation: How to Fight for Truth and Protect Democracy with author Dr. Lee McIntyre. The book presents a chilling description of who creates disinformation, how subscribes to it, and its long term effect on free society. Fortunately, solutions are proposed that can help curb the penetration of disinformation, particularly as it becomes more effective through artificial intelligence. 

    • 53 min
    Therapeutics Controlling Protein Turnover - Dr. Juliet Williams

    Therapeutics Controlling Protein Turnover - Dr. Juliet Williams

    While DNA captures most of the fanfare, proteins are the catalytic and structural superstars of the cell. However, they can also become problematic. Cells have intricate mechanisms to remove damaged or mis-expressed proteins that could be deleterious to cellular function. This process is mediated by a process called ubiquitination, mediated by a special class of proteins called E3 ligases. Ubiquitin is the tag that's added that signals that a protein should be moved to the biochemical garbage can.  Dr. Juliet WIlliams of Kymera describes how their company has used modeling and A.I. to design molecular linkers that connect a protein that needs to be degraded with the machinery to tag it for destruction. The goal of this line of therapeutics is to target a suite of proteins that need to be degraded for normal health and development. Their pipeline contains multiple clinical and pre-clinical trials, and the approach is an exciting complement to other drug discovery methods. 

    • 38 min

Customer Reviews

4.8 out of 5
266 Ratings

266 Ratings

Movie Minifan ,

Great Podcast!

There are not enough fantastic scientific resources like this. It is unbiased, accurate and educational. In this world of science misinformation, I applaud Dr. Flora for being a steady voice for objective evidence-based reason.

blankenstein9191 ,

Great biotech podcast with wide array of topics

This is a fantastic podcast that looks at a broad array of biotech topics ranging from medicine, genetics, agriculture, conservation, and many more. The conversations start at a high enough level to be of value to laymen and non experts but also drill down to specifics that can be deeply informative to those working in biotech. Overall, a really great podcast that anyone interested in or trying to stay up to date with the rapidly evolving biotech landscape should follow

johnburstleton ,

Follow “the science”

the e-mails show that Folta did receive an unrestricted US$25,000 grant last year from Monsanto, which noted that the money “may be used at your discretion in support of your research and outreach projects”. Folta says that the funds are earmarked for a proposed University of Florida programme on communicating biotechnology.

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