43 episodes

The BioInsights Podcast: discussing the challenges of translating novel biologics from bench to clinic to market.

The BioInsights Podcast BioInsights

    • Science
    • 5.0 • 3 Ratings

The BioInsights Podcast: discussing the challenges of translating novel biologics from bench to clinic to market.

    A deep dive in to generative AI applications in I-O

    A deep dive in to generative AI applications in I-O

    Lauren Coyle, Commissioning Editor, Immuno-Oncology Insights, speaks with André Freitas, Senior Lecturer (University of Manchester) and Research Group Leader (Idiap Research Institute/National Biomarker Centre), about the intersection of generative AI and experimental cancer treatments, with a focus on clinical trials, regulatory considerations, and leveraging emerging technologies for a transformative impact in I-O. 

    • 43 min
    Developing novel radioimmunotherapy combinations for lung cancer treatment

    Developing novel radioimmunotherapy combinations for lung cancer treatment

    Lauren Coyle, Commissioning Editor, Immuno-Oncology Insights, speaks to Joe Chang, Clinical Thoracic Oncologist, MD Anderson Cancer Center, University of Texas, who discusses his team’s pioneering work in combining radiation therapy with immunotherapy for lung cancer treatment. He highlights the challenges and promises of optimizing radioimmunotherapy combinations, emphasizing the importance of personalized treatment approaches and collaboration across disciplines to improve patient outcomes.

    • 14 min
    Focusing on the fundamentals: what do and don’t we know about mRNA delivery?

    Focusing on the fundamentals: what do and don’t we know about mRNA delivery?

    As excitement around the evolving field of mRNA continues to grow, there remain some
    fundamental questions to be answered. David McCall, Senior Editor, Nucleic Acid Insights, spoke with Monash University’s Colin Pouton, Professor of Pharmaceutical Biology and Angus Johnston, Associate Professor, ARC Future Fellow about the key limitations and unknowns of current mRNA delivery approaches, and critical areas for further research and innovation to propel the field forward.

    • 45 min
    Navigating genomics and transcriptomics in the immuno-oncology space

    Navigating genomics and transcriptomics in the immuno-oncology space

    Lauren Coyle, Commissioning Editor, Immuno-Oncology Insights, interviews Katie Campbell, Postdoctoral Fellow, Cancer Research Institute, about her current research on genomics, transcriptomics, and spatial profiling to address challenges in the I-O field.

    • 20 min
    Avian influenza and the risk of pandemic

    Avian influenza and the risk of pandemic

    With the potential for avian influenza to transmit and spread amongst humans, an effective vaccine to increase pandemic preparedness is a global priority. Charlotte Barker, Editor, Vaccine Insights, speaks with Mathilde Richard, Principal Investigator & Associate Professor at Erasmus MC, about investigating antigenic evolution of avian influenza viruses, developing better vaccines, and the need for proactive measures to ensure global preparedness in the face of evolving influenza threats.

    • 23 min
    Exploring the landscape of novel targets & pathways in immuno-oncology

    Exploring the landscape of novel targets & pathways in immuno-oncology

    Lauren Coyle, Editor, Immuno-Oncology Insights, speaks to Yvonne McGrath, Chief Scientific Officer, iTeos Therapeutics, about the current and emerging novel targets and pathways for the use of cancer therapy in the I-O field with a focus on small molecules and antibody targets.

    • 17 min

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