21 episodes

The BioInsights Podcast: discussing the challenges of translating novel biologics from bench to clinic to market.

The BioInsights Podcast BioInsights

    • Science
    • 5.0 • 1 Rating

The BioInsights Podcast: discussing the challenges of translating novel biologics from bench to clinic to market.

    Shear ignorance? Think again: breaking the perception of shear within viral vector manufacturing

    Shear ignorance? Think again: breaking the perception of shear within viral vector manufacturing

    The tangential flow filtration (TFF) unit operation in viral vector manufacturing is a critical step on the path to commercialization. In this episode, Merck viral vector experts Ratish Krishnan and Akshat Gupta discuss best practices – and common misconceptions – when establishing process conditions and utilizing different TFF device formats.  

    • 18 min
    CAR-T cells: from cancer to autoimmunity

    CAR-T cells: from cancer to autoimmunity

    Professor Dimitrios Mougiakakos is the director of the Hematology and Oncology department at the Otto-von-Guericke University in Magdeburg, Germany. In this episode, he joins us to discuss the exciting potential for CAR T cell therapy for autoimmune disease and how his team has approached GMP manufacturing in the clinical setting. He explains the challenges faced in setting up cell therapy for systemic lupus erythematosus (SLE), and the future of cell and gene therapy in different indications.

    • 30 min
    Tales, tips & teachable moments from applications support veterans

    Tales, tips & teachable moments from applications support veterans

    Cell and gene therapy scientists are under increasing pressure to achieve results faster and produce cells and cell products more cost-efficiently. Field applications scientists from their major suppliers can provide invaluable support, helping to optimize processes, utilize new platforms and technologies more effectively, and avoid costly errors. In this podcast, three veteran Field Applications Scientists from Corning Life Sciences - Austin Mogen, Catherine Siler, and Chris Suarez - share their expertise and lessons learned over decades of experience. 

    • 25 min
    Access to vaccines: how can we leverage technology innovations to achieve greater vaccine equity?

    Access to vaccines: how can we leverage technology innovations to achieve greater vaccine equity?

    Fatema Kazi works for the WHO, where she helps to assess the public health value of vaccine products and technologies in routine, campaign, and outbreak settings. We caught up with her to discuss how innovations in vaccine technology can help get vaccines to the people who need them.

    • 18 min
    De-risk & accelerate the drug development process for gene therapy

    De-risk & accelerate the drug development process for gene therapy

    In today’s challenging financial environment, it is more important than ever to get key biotech business decisions right first time. One of the most important and topical of these is the choice of CDMO partner. Dr Kim Watanabe, General Manager and Site Head for Patheon Translational Services, a part of the Thermo Fisher Scientific pharma services contract development and manufacturing organizational arm, joins BioInsights to share her advice and insights into optimizing outsourcing strategy.

    • 11 min
    Working Together to Safely Advance Cell & Gene Therapies

    Working Together to Safely Advance Cell & Gene Therapies

    Drug development is a costly and time-consuming process associated with a significant attrition rate in the clinic. Safety is an important factor in this, and is a particular issue for cell and gene therapies. A panel moderated by Dr John Maher of King’s College London and Leucid Bio, and featuring Dr Alastair King, Dr Francisca Neethling, and Dr Andrea Bisso, discuss this highly topical barrier to the further clinical and commercial success of the field.

    • 1 hr

Customer Reviews

5.0 out of 5
1 Rating

1 Rating

Top Podcasts In Science

Hidden Brain
Alie Ward
Sam Harris
Neil deGrasse Tyson
Freakonomics Radio + Stitcher
Mike Carruthers / OmniCast Media / Cumulus Podcast Network

You Might Also Like

Goalhanger Podcasts
Hidden Brain
Vincent Racaniello
ART
Global