36 episodes

Rethinking Science - Let's talk to the leaders of the decentralized science industry about the future of biotech. Brought to you by www.molecule.to

Want to join the stage? Apply as a speaker here: podcast@molecule.to

The DeSci Podcast Molecule

    • Science
    • 4.6 • 7 Ratings

Rethinking Science - Let's talk to the leaders of the decentralized science industry about the future of biotech. Brought to you by www.molecule.to

Want to join the stage? Apply as a speaker here: podcast@molecule.to

    Revolutionizing Drug Development for Rare Diseases Through AI | Alok Tayi

    Revolutionizing Drug Development for Rare Diseases Through AI | Alok Tayi

    In this episode, we have the pleasure of hosting Alok Tayi, the co-founder of Vibe Bio.Vibe Bio is a life science company dedicated to investing in biotech firms, with a special focus on rare and overlooked diseases.



    In this episode, Alok shares his personal story of how medical conditions in his family led to the creation of Vibe Bio, and how the company aims to identify diseases with unmet needs, leveraging AI to find medicines with the highest chances of providing cures.



    We discuss the complexities of drug development, the advantages of DAOs as an organizational structure and common misconceptions within the Biopharma industry. Alok also shares his insights on the transformative role of AI in drug discovery, discussing its utilization, the methods used for training AI models, the issue of AI bias, and the current limitations and challenges faced in leveraging AI to advance drug development.



    Feel free to navigate through any of the topics discussed in the podcast using the timestamps below.

    ___

    ⭐ Timestamps:

    0:00 Intro

    01:51 What led you to create Vibe

    02:52 Diseases Vibe Focuses On

    04:37 Complexities in Drug Development

    7:49 Advantages of DAOs

    12:00 Misconceptions in Academia & the Private Sector

    16:53 Areas you’re willing to explore with more funding.

    23:59 Utilizing AI tools in Drug Discovery

    28:50 Bias in AI

    32:54 AI Training Methods

    36:58 Limits of AI in Drug Discovery

    39:56 Implicit Knowledge in Drug Development

    49:30 Outro



    ____

    If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.



    If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at podcast@molecule.to



    Special thanks to

    Lea: https://twitter.com/lealeata

    Alok: https://twitter.com/aloktayi

    Learn more about Vibe Bio here: https://vibebio.com/



    ____

    Let's connect:

    Website: https://bit.ly/3d6nh2C

    X: https://twitter.com/Molecule_dao

    Discord: https://discord.com/invite/moleculedao

    • 49 min
    Decentralizing Healthcare Data Management: Hippocrat's Vision for Data Sovereignty

    Decentralizing Healthcare Data Management: Hippocrat's Vision for Data Sovereignty

    Welcome to another episode of the DeSci Podcast. Today, we're joined by Justin, Head of Growth at Hippocrat, a collaborative healthcare data protocol that aims to transform healthcare by empowering individuals to take control of their health data through blockchain and zero-knowledge proof technologies.



    In this episode, we discuss the importance of data sovereignty, exploring how Hippocrat's innovative approach ensures secure and private data management, enabling safe and transparent data sharing with healthcare providers.



    Justin emphasizes the need for decentralized data provision in healthcare, stressing that shifting from centralized to decentralized data management addresses the longstanding issue of individuals lack of control over their health data, which in turn advances personalized healthcare and research.



    We also explore Hippocrat's collaboration with Research HUB, aimed at identifying potential populations and regions where Hippocrat's telemedicine application, ‘Hippodoc’, could be effectively deployed to bridge healthcare accessibility gaps.



    Feel free to navigate through any of the topics discussed in the podcast using the timestamps below.

    ___

    ⭐ Timestamps:

    0:00 Intro

    1:28 About Hippocrat

    2:37 Why data sovereignty is important

    7:55 The inspiration behind Hippocrat

    11:48 Moving from Web 2 to Web 3 healthcare

    13:39 How Hippocrat improves Data security

    22:27 $HPO token utility and upcoming airdrop

    26:58 Collaboration with Research HUB

    38:25 How the Hippodoc app works

    41:27 Hippocrat role in the DeSci space

    45:30 Hippocrat in 10 years

    49:18 How to get involved



    ____

    If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.



    If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at podcast@molecule.to



    Special thanks to

    Ella McCarthy-Page: https://twitter.com/EMcCarthyPage

    Justin Kim: (email: justin@hippocrat.io / telegram: just_in_1)

    Special Airdrop for DeSci Podcast listeners: https://gleam.io/cLiQO/100-hippocrat-x-desci-podcast-giveaway

    Learn more about Hippocrat here: https://link3.to/hippocrat



    ____

    Let's connect:

    Website: https://bit.ly/3d6nh2C

    X: https://twitter.com/Molecule_dao

    Discord: https://discord.com/invite/moleculedao

    • 52 min
    Revolutionizing Research and Innovation Through Blockchain Technology

    Revolutionizing Research and Innovation Through Blockchain Technology

    In this episode we're joined by Dr. Sönke Bartling, Founder of Blockchain for Science, an initiative that aims to open up science and knowledge creation through web3.



    In this episode, we explore Decentralized Science (DeSci) and its potential to revolutionize research, publishing, and innovation! We dive deep into how blockchain technology can transform scholarly publishing by making it more transparent, efficient, and trustworthy.



    We also discuss how DeSci can address funding inequality by supporting both high-profile topics, such as longevity research, and smaller yet vital fields. This, in turn, enables DeSci to promote diversity in research and unlock breakthroughs in overlooked areas.



    We further discuss how DeSci can revolutionize the peer review process and explore the future of patents in a DeSci landscape, where research is incentivized without hindering collaboration, and how this can lead to more innovative scientific discoveries.



    Feel free to navigate through the various topics covered in the Podcast using the timestamps provided below.

    ___

    ⭐ Timestamps:

    0:00 Intro

    1:46 Blockchains in the Future of Science and Research

    4:25 Blockchain Adoption in Publishing

    5:45 Underappreciated Aspects of DeSci

    12:06 Radical Guidelines for Web3

    17:19 Transitioning more Scientists to DeSci

    25:26 What limits Institutional Change with Technology

    30:22 Incentivising Foolproof DeSci

    33:12 Plausibility and Reproducibility in Peer Review

    36:16 Standards for Peer Review

    39:14 DeSci for Publishing

    40:25 The Private Sector and Academia

    43:59 Non-monopolizing Patents with Web3

    46:36 Further Questions



    ____

    If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.



    If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at podcast@molecule.to



    Special thanks to

    Lea Degen: https://twitter.com/lealeata

    Dr. Sönke Bartling: https://twitter.com/soenkeba

    ____

    Let's connect:

    Website: https://bit.ly/3d6nh2C

    X: https://twitter.com/Molecule_dao

    Discord: https://discord.com/invite/moleculedao

    • 48 min
    Diagnosing the drug R&D productivity decline with Dr Jack Scannell

    Diagnosing the drug R&D productivity decline with Dr Jack Scannell

    In this episode, we discuss the problem of declining R&D efficiency with Dr. Jack Scannell, a scientist and entrepreneur who is well known for coining the term “Eroom’s law,” which highlights the decline in pharmaceutical research and development (R&D) productivity over several decades.



    In this episode, Jack sheds light on the root causes of this decline, beginning with a critique of the poor quality of diagnosis surrounding the R&D productivity problem.

    He also talks about the challenges in accurately measuring progress in drug research, highlighting the "measurement problem" in the drug industry. Jack suggests adopting a model akin to the "Stern Review” to improve the diagnosis of these challenges.



    Jack also addresses topics such as the shift in the frequency of serendipitous drug discoveries, the Eroom’s law article, the entanglement of science, money and drug development and many more.



    Feel free to navigate through any of the topics discussed in the Podcast using the timestamps below.

    ___

    ⭐ Timestamps:

    0:00 Intro

    01:40 Poor quality of diagnosis of the R&D productivity problem

    04:01 The measurement problem

    09:21 Chesterton’s fence of R&D

    14:38 Science, Drug development, Money.

    20:46 The role of Serendipity in drug discovery

    26:34 Economics in the drug industry.

    34:43 Implicit knowledge within Biotech

    41:43 Eroom's Law paper



    ____

    If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.



    If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at podcast@molecule.to



    Special thanks to

    Lea Degen: https://twitter.com/lealeata

    Jack Scannell: https://twitter.com/JackScannell13

    ____

    Let's connect:

    Website: https://bit.ly/3d6nh2C

    X: https://twitter.com/Molecule_dao

    Discord: https://discord.com/invite/moleculedao

    • 47 min
    How ResearchHub Makes Open Science Rewarding by Reinventing Academic Incentives

    How ResearchHub Makes Open Science Rewarding by Reinventing Academic Incentives

    Welcome to another episode of the DeSci Podcast. Today, we were joined by Jeffrey Koury, Director & Business Development Lead at ResearchHub, and Jonathan Heppner, Marketing & Social Media Lead.



    ResearchHub is a platform designed to accelerate the pace of scientific research by providing a modern mobile and web application where people can collaborate on scientific research more efficiently. It aims to make scientific research accessible, collaborative, and prioritized for everyone.



    In this episode, we delved into the shortcomings of the current scientific research model and the need to make science open to everyone.



    Our dialogue centered on advocating for a shift from the traditional model towards a more inclusive and transparent system. Central to this shift is the necessity of building better incentive structures, which would drive collaboration among scientists and facilitate accelerated progress in scientific research.



    Feel free to navigate through any of the topics discussed in the Podcast using the timestamps below.

    ___

    ⭐ Timestamps:

    0:00 Intro

    1:30 What is Research Hub?

    03:05 Onboarding process.

    05:40 What drove your interest in building Research Hub?

    12:16 Past efforts in promoting open science

    18:32 The role of Research Hub in scientific literature

    26:19 How Research Hub differs from traditional journals

    35:14 Public versus Anonymous Peer Review

    39:20 Most contentious topics within your field

    48:50 Ensuring high quality science

    52:35 Why books are important

    59:13 How to get involved

    59:47 How Research Hub has evolved over the years

    1:05:13 Outro

    ____

    If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.



    If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at podcast@molecule.to



    Special thanks to

    Lea Degen: https://twitter.com/lealeata

    Jeffrey Koury: https://twitter.com/jeffyfish9

    Jonathan Heppner: https://twitter.com/EnactJohnny

    ____

    Let's connect:

    Website: https://bit.ly/3d6nh2C

    X: https://twitter.com/Molecule_dao

    Discord: https://discord.com/invite/moleculedao

    • 1 hr 6 min
    Seemay Chou on Arcadia's Revolutionary Approach to Science and Entrepreneurship

    Seemay Chou on Arcadia's Revolutionary Approach to Science and Entrepreneurship

    Today we are delighted to host Seemay Chow, Co-founder and CEO of Arcadia Science, a for-profit research institute with a specific focus on novel model organisms that haven't been traditionally studied in the lab and translating discoveries into commercial ventures.



    In this episode, we discuss Arcadia’s mission, structure and approach, emphasizing the importance of providing scientists with the context needed to understand the practical applications of their research. Seemay explains how this approach fosters a different kind of creativity among researchers, thus increasing the likelihood of research success.



    We also explore the limitations researchers face in the traditional setting while further highlighting the strengths and weaknesses of Academia and industry. Other topics we touched on include notions of diversity in science, strategies for spotting the best talents and ideas to fund, and many more.



    Feel free to navigate through the various topics covered in the Podcast using the timestamps provided below.



    ___

    ⭐ Timestamps:

    0:00 Intro.

    0:49 Effects of running a for-profit venture on Arcadia’s structure.

    3:05 What is Arcadia?

    7:35 Researchers limitations in Academia.

    11:45 Academia vs the private sector.

    16:21 Insights gained from building Arcadia.

    27:54 Arcadia structure.

    30:38 Diversity in science.

    35:24 Strategies for discovering the best talents.

    43:28 Contextualizing science.

    49:50 Outro.

    ____

    If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.



    If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at podcast@molecule.to



    Special thanks to

    Lea Degen: https://twitter.com/lealeata

    Seemay Chou: https://twitter.com/seemaychou

    ____

    Let's connect:

    Website: https://bit.ly/3d6nh2C

    X: https://twitter.com/Molecule_dao

    Discord: https://discord.com/invite/moleculedao

    • 50 min

Customer Reviews

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