29 episodes
The Inner Workings of Cells, Winter 2008 Ken Kaplan
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- Science
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5.0 • 5 Ratings
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Cellular function lies at the root of all complex and simple biological systems. This course will expose you to the fundamental mechanisms that allow cells to maintain the system of proteins and biomolecules required for them to replicate with high fidelity, to maintain stable functional states, to differentiate in response to external cues and to ultimately form complex organizations of cells (i.e., tissues). We will apply an experimental approach to a classic problem in cell biology. We will master “blackboard” experimental techniques to allow us to explore the remarkable transformation of a monolayer of cells after being “wounded.” Under such conditions, cells surrounding the wound change their organization and programming in order to migrate, divide, and differentiate to fill in the wound.
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Review for Final Exam
Review for Final Exam: This class covers all topics discussed in the course, with an emphasis on cell signaling.
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Cell Signaling & Cancer Cells
Lecture 28: The instructor reviews some major pathways dealing with signal transduction and an application of principles learned to cancerous cells.
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Signal Transduction
Lecture 27: Kaplan continues his discussion of signal transduction, the role of signals in cell migration, and the ability of cells to see which direction to move.
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Signal Transduction
Lecture 26: Kaplan talks about properties of signaling modules and different kinds of membrane receptors that interpret signals from outside the cell.
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Cell Signaling
Lecture 25: This class is a wrap-up of cell division and checkpoints in the regulatory cycle, and introduction to how cells interpret various biochemical signals.
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Cell Division
Lecture 24: Students learn more about cell division, and introduction to cell checkpoints along the regulatory cycle.
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