878 episodes

TWiV is a weekly netcast about viruses - the kind that make you sick. Brought to you by four university professors and a science writer.

This Week in Virology Vincent Racaniello

    • Science
    • 4.8 • 95 Ratings

TWiV is a weekly netcast about viruses - the kind that make you sick. Brought to you by four university professors and a science writer.

    The vax of life with John Mascola

    The vax of life with John Mascola

    John Mascola joins TWiV to discuss the history and mission of the NIH Vaccine Research Center, how it prepared for devising pandemic vaccines, and development of the COVID-19 vaccines.
    Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker
    Guest: John Mascola
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    Links for this episode Accelerated COVID-19 vaccine development (Immunity) Letters read on TWiV 858 Timestamps by Jolene. Thanks! Weekly Picks Brianne – How Sesame Street is Handling the Pandemic
    Rich – Zamboni: How it works
    Alan – How lightning starts
    Vincent – Buon-A-Petitti
    Listener Picks Meika –Wordle
    Intro music is by Ronald Jenkees

    Send your virology questions and comments to twiv@microbe.tv

    • 1 hr 48 min
    Not just antibody, Jon Yewdell

    Not just antibody, Jon Yewdell

    Jon Yewdell returns to TWiV to discuss how antibodies are made, vaccination against SARS-CoV-2, antigenic variation of the virus, booster shots, and more.
    Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker
    Guest: Jon Yewdell
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    Links for this episode Jon Yewdell on TWiV 208, 467, 597, 620 Letters read on TWiV 857 Timestamps by Jolene. Thanks! Weekly Picks Jon – The Premonition by Michael Lewis
    Dickson – Nature photographer of the year 2021
    Brianne – Should BioBank Volunteers Be Warned About Mutations?
    Rich – Czech singer Hanka Horká dies after intentionally getting infected by the coronavirusand Dena Dietrich Dies at 91
    Vincent – Cuore di Cioccolato
    Listener Picks Bronwen – Schools must stay open
    John – Pandemic humor
    Intro music is by Ronald Jenkees

    Send your virology questions and comments to twiv@microbe.tv

    • 1 hr 39 min
    COVID-19 clinical update #98 with Dr. Daniel Griffin

    COVID-19 clinical update #98 with Dr. Daniel Griffin

    In COVID-19 clinical update #98, Daniel Griffin reviews COVID-19 in South Africa, recognition of Omicron by ancestral T cells, booster effectiveness against disease, infection and vaccination in pregnant women, early Remdesivir to prevent progression to severe disease, management of hospitalized adults, Tocilizumab in hospitalized patients, vaccination and long COVID, and the true toll of the pandemic.
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    Download TWiV 853 (58 MB .mp3, 48 min)
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    Links for this episode COVID-19 in South Africa (pdf) Ancestral T cells recognize Omicron (Nat Med) Booster effectiveness against COVID-19, England (Nat Med) Cases and hospitalization by vaccination status (MMWR) Infection and vaccination in pregnant women, Scotland (Nat Med) Early Remdesivir to prevent progression to severe disease (NEJM) Management of hospitalized adults (NIH) Tocilizumab in hospitalized patients (Resp Care) Vaccination and long COVID in Israel (medRxiv) Pandemic true death toll (Nature) Internship at Parasites Without Borders (pdf) Letters read on TWiV 856 Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees

    Send your questions for Dr. Griffin to daniel@microbe.tv

    • 51 min
    T time with Alessandro Sette

    T time with Alessandro Sette

    Alessandro Sette returns to TWiV to discuss the observation that SARS-CoV-2 vaccination induces T cells that are able to cross-recognize variants Alpha to Omicron.
    Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker
    Guest: Alessandro Sette
    Subscribe (free): iTunes, Google Podcasts, RSS, email
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    Links for this episode Travel Award Applications (ASV) 3:20 Impact of variants on T cells (Cell Rep Med) Timestamps by Jolene. Thanks! Letters read on TWiV 855 Weekly Picks Brianne – 75 years of research on human diseases in 1 minute
    Kathy – 10 second video of COVID-19 spread
    Rich – Diffraction spike
    Vincent – John’s Furniture Repair and Transcend Furniture Gallery
    Listener Picks Alison – FDA drug shortages
    Ingrid – One woman’s mission to get vaccines to her rural Alabama town
    Intro music is by Ronald Jenkees

    Send your virology questions and comments to twiv@microbe.tv

    • 1 hr 36 min
    Omicron is evasive

    Omicron is evasive

    TWiV reviews findings that increased fitness of the Omicron variant is due to immune evasion, not an increase in intrinsic transmissibility, and determination of infectious viral load in patients infected with wild type, Delta and Omicron viruses reveals lack of correlation with RNA loads determined by RT-PCR, similar levels of shedding among Delta and Omicron, and greatly reduced shedding in vaccinated people.
    Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker
    Subscribe (free): iTunes, Google Podcasts, RSS, email
    Become a patron of TWiV!
    Links for this episode Travel Award Applications (ASV) 2:11 Omicron transmission in Danish households (medRxiv) Infectious viral load in vaccinated and unvaccinated patients (medRxiv) Fred Murphy on TWiV 625 Timestamps by Jolene. Thanks! Weekly Picks Dickson – Favorite Science Photos of 2021
    Brianne – Viruses, Vaccines, and COVID-19 videos from American Museum of Natural History
    Kathy – Klompas et al. “Current insights into respiratory virus transmission…”
    Rich – Leviathan Falls by James S.A. Corey
    Vincent – Ebola (1996) by David Molesky at The Incubator
    Listener Picks Randall – Robert Malone & Peter McCullough: A litany of untruths
    Suellen – Omicron and the case of the hidden evolution – Understanding Evolution
    Intro music is by Ronald Jenkees

    Send your virology questions and comments to twiv@microbe.tv

    • 2 hr 5 min
    COVID-19 clinical update #97 with Dr. Daniel Griffin

    COVID-19 clinical update #97 with Dr. Daniel Griffin

    In COVID-19 clinical update #97, Daniel Griffin covers immunity after infection recognized by CDC, outcomes before and after Omicron, infectious viral load in Delta vs Omicron, PCR vs rapid antigen tests, booster interval shortened to 5 months, risk factors for severe outcomes in vaccinated, cross-reactive memory T cells, vaccine effectiveness vs MIS-C, and Rivaroxiban for thromboprophylaxis.
    Subscribe (free): iTunes, Google Podcasts, RSS, email
    Become a patron of TWiV!
    Links for this episode Quarantine and isolation (CDC) Outcomes before and after Omicron (medRxiv) Infectious viral load in Delta vs Omicron infections (medRxiv) PCR vs rapid antigen test (medRxiv) Booster interval to 5 months (FDA) Cross-reactive memory T cells (Nat Comm) Risk factors for severe outcomes in vaccinated (MMWR) Vaccine effectiveness vs MIS-C (MMWR) Cross-reactive T cells to Omicron from vaccines (medRxiv) Rivaroxiban for thromboprophylaxis (Lancet) Letters read on TWiV 853 Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees

    Send your questions for Dr. Griffin to daniel@microbe.tv

    • 53 min

Customer Reviews

4.8 out of 5
95 Ratings

95 Ratings

scareduck ,

Excellent, approachable for the curious outsider

I have zero background in biology, and find this show does a great deal to make this vital subject comprehensible to people at all levels, while providing useful details and insights from working area experts in the field. Terrific show.

Ms lauderdale ,

COVID Parties for unvaxxed Healthcare Professionals

A questions was asked “should healthcare professionals that have already had Covid and subsequently developed antibodies and immunity be exempt from Covid vaccine mandates?” Their answer was to dance around the science of natural immunity, even though they well know it’s at-least as protective, then they gave the absurd answer to the REAL reason to mandate them to get vaccines was to prevent them from trying to contract Covid at a “Covid Infection Party”. If that doesn’t set off red flags for pushing their agenda I don’t know what does. They claimed they don’t want to encourage this practice, as if Doctors and Nurses have been doing this. What a lie and a breach of trust from “the science”. You should be ashamed to claim such a thing.

Squash1789 ,

Toxic podcast for humanity

This podcast is hosted by the virologists that have championed gain of function research for years. “Episode 364: It’s not SARS 2.0" speaks to Ralph Baric about his research into manipulating SARS related coronaviruses in the Wuhan Institute of Virology.
In epsideo 614, Speaking to Peter Daszek in Nov 2019 Peter says "coronaviruses are pretty good... you can manipulate them in the lab pretty easily... the spiked drives a lot about what happens. you can get the sequence you can build the protein, we work with Ralph Barrack at UNC to do this, insert into the back bone of another virus and do some work in a lab."
This podcast should not be used to learn anything. This podcast is only an archive of evidence about the dangerous work these scientists have done in wuhan for th 6 years leading up to the SARS-COV-2 (COVID-19) emerged just outside of the lab that they were doing their research in.

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