11 episodes

Join DNA Dan as he dives deep into the world of genetics, genomics, DNA, and the future of precision genomic medicine. Dan discusses topics ranging from health and ancestry genetic testing, forensic genetics, genetics and mental health, common myths about genetics, and more. DNA Dan, SCU Professor of Genomics, Dan Handley, M.S., Ph.D., shares his knowledge from his over 30 years of experience in the world of advanced genomics research and biotechnology. For more information about Southern California University of Health Science's Master of Science Program in Human Genetics and Genomics, please visit our website. https://bit.ly/SCU-DNA_Dan

DNA Dan - A Genetics & Genomics Podcast DNA Dan

    • Education

Join DNA Dan as he dives deep into the world of genetics, genomics, DNA, and the future of precision genomic medicine. Dan discusses topics ranging from health and ancestry genetic testing, forensic genetics, genetics and mental health, common myths about genetics, and more. DNA Dan, SCU Professor of Genomics, Dan Handley, M.S., Ph.D., shares his knowledge from his over 30 years of experience in the world of advanced genomics research and biotechnology. For more information about Southern California University of Health Science's Master of Science Program in Human Genetics and Genomics, please visit our website. https://bit.ly/SCU-DNA_Dan

    11. Alternative Splicing - Nature's Mad Scientist

    11. Alternative Splicing - Nature's Mad Scientist

    In the last episode on the central dogma of molecular biology, DNA Dan discussed the information flow of DNA, to RNA, to amino acid sequences that make up proteins. 

    In this episode, Dr. Handley discusses proteins - the work horses of the body, and the extensive roles they play in our bodies. By last known count, there are around 20,000 protein coding genes in the human coding genome that make up and operate the human body. How can these 20,000  genes produce over 100,000 proteins? This is where nature, the mad scientist, comes in. 
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    Join DNA Dan each month as he dives deep into the world of genetics, genomics, DNA, and the future of precision genomic medicine. Dan discusses health and ancestry genetic testing, forensic genetics, genetics and mental health, common myths about genetics, and more. 

    DNA Dan, SCU Professor of Genomics, Dan Handley, M.S., Ph.D., shares his knowledge from his over 30 years of experience in the world of advanced genomics research and biotechnology. 

    Please visit our website for more information about Southern California University of Health Science's Master of Science Program in Human Genetics & Genomics. https://bit.ly/SCU-DNA_Dan

    • 6 min
    10. The Central Dogma of Molecular Biology

    10. The Central Dogma of Molecular Biology

    In episodes 2, 3 and 4 of this podcast, we've learned that DNA is determined to be the molecule of inheritance, as well as how its structure is determined.  What DNA Dan hasn't yet discussed is what DNA actually does. Or, if DNA is the so called "code of life," how is its code being read? And how is that information put into action? That brings us to the central dogma of molecular biology. 

    In this episode, DNA Dan discusses the "central dogma of molecular biology," information theory of English physicist, Francis Crick in the 1950s, the early principles he was trying to convey, and then brings us up to speed on what we know about the information flow of DNA, RNA and protein biological processes, today.
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    Join DNA Dan each month as he dives deep into the world of genetics, genomics, DNA, and the future of precision genomic medicine. Dan discusses health and ancestry genetic testing, forensic genetics, genetics and mental health, common myths about genetics, and more. 

    DNA Dan, SCU Professor of Genomics, Dan Handley, M.S., Ph.D., shares his knowledge from his over 30 years of experience in the world of advanced genomics research and biotechnology. 

    Please visit our website for more information about Southern California University of Health Science's Master of Science Program in Human Genetics & Genomics. https://bit.ly/SCU-DNA_Dan

    • 7 min
    9. The Other Human Genome

    9. The Other Human Genome

    If you think back to your early years of biology class, you may remember learning about tiny cellular energy factories, called mitochondira. Mitochondria are microscopic powerhouses hiding within most cells and they play a huge role in our health. Damaged mitochondria can lead to a host of health issues. But healthy mitochondria can result in optimal aging. DNA Dan explains more on mitochondria, and how better understandings may help advance new approaches in the study of some diseases.
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    Join DNA Dan each month as he dives deep into the world of genetics, genomics, DNA, and the future of precision genomic medicine. Dan discusses health and ancestry genetic testing, forensic genetics, genetics and mental health, common myths about genetics, and more. 

    DNA Dan, SCU Professor of Genomics, Dan Handley, M.S., Ph.D., shares his knowledge from his over 30 years of experience in the world of advanced genomics research and biotechnology. 

    Please visit our website for more information about Southern California University of Health Science's Master of Science Program in Human Genetics & Genomics. https://bit.ly/SCU-DNA_Dan

    • 6 min
    8. Shotgun Sequencing and the Human Genome Project

    8. Shotgun Sequencing and the Human Genome Project

    Over the 1960s through 1980s, more was learned about the structure of chromosomes and the functions of some genes. However, we did not have a comprehensive map of the entire human genome. Learn how molecular biology techniques become more sophisticated, and scientists could start determining the nucleotide sequence of small portions of chromosomes.
    ------------------------------------------
    Join DNA Dan each month as he dives deep into the world of genetics, genomics, DNA, and the future of precision genomic medicine. Dan discusses health and ancestry genetic testing, forensic genetics, genetics and mental health, common myths about genetics, and more. 

    DNA Dan, SCU Professor of Genomics, Dan Handley, M.S., Ph.D., shares his knowledge from his over 30 years of experience in the world of advanced genomics research and biotechnology. 

    Please visit our website for more information about Southern California University of Health Science's Master of Science Program in Human Genetics & Genomics. https://bit.ly/SCU-DNA_Dan

    • 6 min
    7. How to Get Six Feet of DNA into a Six Micron Suitcase

    7. How to Get Six Feet of DNA into a Six Micron Suitcase

    In each nucleus of a human cell, the total length of DNA contained in it is about 6 feet long. Now, the size of a nucleus in a human cell is only 6 microns in width. A micron, otherwise called a micrometer, is 1 one-millionth of a meter. To put this in perspective, the average human hair is about 100 micrometers in diameter, and a grain of salt is 500 micrometers in width, give or take.  
    So how are 6 feet of DNA packed inside such a tiny space? Find out with DNA Dan.
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    Join DNA Dan each month as he dives deep into the world of genetics, genomics, DNA, and the future of precision genomic medicine. Dan discusses health and ancestry genetic testing, forensic genetics, genetics and mental health, common myths about genetics, and more. 

    DNA Dan, SCU Professor of Genomics, Dan Handley, M.S., Ph.D., shares his knowledge from his over 30 years of experience in the world of advanced genomics research and biotechnology. 

    Please visit our website for more information about Southern California University of Health Science's Master of Science Program in Human Genetics & Genomics. https://bit.ly/SCU-DNA_Dan

    • 4 min
    6. What We Now Know About the Structure of DNA

    6. What We Now Know About the Structure of DNA

    Today we understand much more detail about the structure of DNA. It turns out that Watson, Crick, Wilkins, Franklin, and the many others involved gave essentially the correct answer about the DNA molecule and how it is structured. 
    ------------------------------------------
    Join DNA Dan each month as he dives deep into the world of genetics, genomics, DNA, and the future of precision genomic medicine. Dan discusses health and ancestry genetic testing, forensic genetics, genetics and mental health, common myths about genetics, and more. 

    DNA Dan, SCU Professor of Genomics, Dan Handley, M.S., Ph.D., shares his knowledge from his over 30 years of experience in the world of advanced genomics research and biotechnology. 

    Please visit our website for more information about Southern California University of Health Science's Master of Science Program in Human Genetics & Genomics. https://bit.ly/SCU-DNA_Dan

    • 5 min

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