Nothing Ventured Aarish Shah - EmergeONE

On this episode of Nothing Ventured, host Aarish Shah sits down with
George Askew and Sam Ettelaie, co-founders of Thema, a platform
supporting emerging managers in launching venture capital strategies.
They discuss fund structuring, regulation, and the impact of patient
capital on the ecosystem. With Thema already attracting over 450 funds
within weeks of launching, George and Sam shed light on the importance
of backing those who aim to build management businesses. Tune in to gain
insights from industry experts and explore the stories shaping the
venture capital landscape.

🕒 Time stamps -
00:25 - Thema's Role in Supporting Emerging Managers
01:50 - The Challenges for Emerging Managers
03:19 - Fund Structuring and Regulation
05:03 - The Importance of Guidance for New Fund Managers
06:05 - Thema's Approach to Supporting Fund Managers
07:14 - The Need for Capital and Structuring Support
08:17 - The Role of LPs and the Fundraising Process
09:10 - The Ecosystem's Gatekeeping and Transparency
10:17 - Co-Investment Opportunities and LP Interests
11:42 - Supporting Underrepresented Emerging Managers
12:02 - Operator Backgrounds in Venture Capital
13:15 - The Genesis of Thema and Co-Founder Synergy
14:47 - The Return Profile for Emerging Managers
16:09 - The Importance of Fund Structuring
17:22 - The Market's Current State and Advice for Allocators
18:48 - The Risk Aversion in European Venture Ecosystem
20:19 - The Role of LPs in Supporting Emerging Managers
21:44 - The Value of Operator Experience for GPs
23:17 - The Importance of Differentiation for Emerging Managers
24:50 - The Patient Capital and Risk Aversion in Europe
26:48 - The UK Venture Ecosystem and Lessons from the US
28:08 - The Role of GP Seeding in the Emerging Manager Ecosystem
30:35 - The Evolution of Family Offices in Venture
32:11 - Final Advice for Emerging Managers
33:30 - The UK vs. US Emerging Manager Ecosystem
34:47 - The Potential of the UK Venture Ecosystem
36:36 - The Excitement for Emerging Managers and Innovation
38:24 - How to Connect with Thema and Closing Remarks

In this episode of Nothing Ventured, host Aarish Shah interviews Sean
Williams, the founder and CEO of Autogen AI. Sean shares insights on
learning from failures, the role of managers in delivering results,
staying focused amidst distractions, and the significance of linguistic
engineering in business. He also discusses his journey with investors
and the importance of context windows in team scaling. Tune in for a
deep dive into the world of generative AI and venture capital with Sean
Williams.

⏱️ Timestamps:01:01 - Introducing Sean Williams of Autogen AI01:22 - Sean's Approach to Learning and Management02:04 - Sean's Background and Autogen AI's Mission02:25 - Reflecting on Past Success and Lessons Learned03:52 - Building a Business with a Clear Exit Strategy04:13 - The Philosophy of Building a Business05:02 - The Confidence in a Four-Year Exit Plan06:02 - The Venture Capital Mindset vs. Strategic Growth07:04 - The Importance of Sticking to a Business Plan08:11 - The Shift from Corndell to Autogen AI09:36 - The Current Venture Capital Landscape10:07 - Autogen AI's Fundraising Journey11:11 - Choosing the Right Venture Capital Partner12:39 - The Role of Investors Beyond Capital13:31 - Autogen AI's Decision to Take Venture Capital14:18 - Autogen AI's Target Customer Base15:29 - The Process of Raising Capital Without Fundraising16:07 - Filtering Through VC Approaches and Selecting Blossom Capital17:49 - The Importance of Choosing the Right Investors18:54 - The Potential Need for Future Capital19:57 - The UK's Perception of Tech Business Success21:03 - Autogen AI's Approach to Scaling Internationally22:10 - The Early Adoption of Generative AI23:14 - The Importance of Building Something People Want24:21 - The Future of Large Language Models and Linguistic Engineering25:07 - Sponsor Break: Emerge One25:30 - The Role of Humanities Graduates in AI Development26:56 - The UK's Tech Ecosystem and Ambition28:31 - The Importance of Customer Feedback in Product Development29:51 - Advice for Young Founders and Challenges in Business Growth31:00 - The Intersection of Humanities and Technology in AI32:04 - The Concept of Linguistic Engineering33:03 - The Practical Application of Large Language Models34:02 - Hiring Humanities Graduates for AI Development35:06 - The Importance of Customer-Centric Product Development36:08 - The Future of Specialized AI Applications37:14 - The Role of Prompt Engineers and Humanities in AI38:43 - Final Advice for Founders and Personal Business Concerns

In this episode of Nothing Ventured, Aarish Shah sits down with Enis
Hulli, a general partner at 500 Emerging Europe. They discuss Enis'
journey from listening to VC podcasts to launching a fund, his shift
from being risk-averse to investing, and the importance of boots on the
ground for pre-seed and seed investments. They also delve into how 500
Emerging Europe differs from the global family, the challenges of equity
financing in Europe, and the dynamics of startup culture in emerging
Europe. Tune in for insights on venture investing and navigating the
unique landscape of emerging markets.

⏱️ Timestamps:
00:00 - Introduction and Sponsor Message01:11 - Guest Introduction: Enes Huli02:21 - Enes' Transition from HVAC to Angel Investing04:42 - Risk Aversion and Entrepreneurship07:20 - Sales Experience and Self-Confidence09:28 - Founder Types and Portfolio Balance10:58 - The Path from Entrepreneur to Investor12:06 - 500 Global and 500 Emerging Europe Model14:23 - The Unique Approach of 500 Emerging Europe17:02 - Portfolio Strategy and Global Competition19:04 - The Population Paradox in Venture20:24 - Equity Financing Deficit in Emerging Europe22:49 - The Pathway to Closing the Equity Gap25:51 - Early Adopters and Scaling Challenges27:20 - Advice for Founders in Emerging Markets30:01 - Americanizing Startup Culture33:35 - How to Connect with Enes Huli

This episode of Nothing Ventured features a discussion with Mohamed
Abou-Alam about the challenges and strategies in the tech and venture
ecosystem. They explore topics like managing chronic conditions with
data, building multidisciplinary teams, quantifying impact to LPs,
regulatory and commercial outcomes, transitioning roles in the industry,
and adapting to the competitive landscape. Tune in for valuable
insights into the world of venture capital and tech innovation.

🕒 Time stamps -
01:52 - The Challenges of Hard Tech in Medicine
02:43 - Precision's Approach to Managing Heart Conditions
03:29 - Mohammed's Non-Medical Background and Precision's Hardware
04:02 - Why Precision's Solution is Innovative
05:06 - Mohammed's Journey from VC to Precision
07:12 - The Importance of Multidisciplinary Teams
09:10 - Building a Holistic Team at Precision
10:05 - The Role of Finance in Startups
11:07 - Mission-Driven Businesses in Health Sector
13:22 - Proactive Medicine and Personalization
14:15 - Transition from Samsung to VC and Operating Roles
17:08 - The Importance of Understanding Different Perspectives
19:13 - Mohammed's Transition to CEO at Precision
22:02 - The Decision to Take on the CEO Role
23:23 - The Balance Between Operator and Finance-Driven VCs
24:36 - The Complexities of Medical Device Startups
25:18 - The Multi-Stakeholder Model in Health Tech
27:27 - R&D and Commercialization in Regulated Businesses
28:54 - Innovate UK Grant and Funding R&D Businesses
31:25 - Tips for Securing Grants and Funding
33:02 - The Importance of Complementarity in Competitive Landscapes
35:28 - The Unique Challenges of Multi-Stakeholder Industries
37:47 - The Value of Grants Beyond Funding
39:10 - The Role of Validation in Fundraising
40:05 - Choosing the Right Grants and Using Consultants
42:03 - The Benefits of Multiple Assessors for Grants
43:11 - The Validation Aspect of Grants in Fundraising
44:02 - Keeping a Team Motivated and Malleable
45:22 - Where to Find Precision Cardiovascular Online

In this episode of Nothing Ventured, we delve into the world of tech bio
with co-founders Nik Sharma and Mo Alomari from BioCortex. They discuss
reflecting biology in silico, NASA-inspired strategies, and the
importance of trust in co-founder relationships. Learn how BioCortex is
revolutionizing therapeutic development with insights backed by Hoxton
and Sofinova. Tune in for a deep dive into the intersection of
technology and biotech with these innovative minds.

🕒 Time stamps -
01:01 - Introducing Guests Nick Sharma and Mo Al-Omari
01:55 - Emulation vs. Simulation in Tech Bio
02:16 - BioCortex: A Tech Bio Company Overview
02:27 - Founders' Backgrounds and Expertise
03:09 - BioCortex's Vision and Technology
03:33 - Personalizing Medication Efficacy with BioCortex
04:15 - Broader Applications of BioCortex Technology
04:31 - Carbon Knowledge and Carbon Mirror Technologies
05:03 - Emulation in Aerospace Applied to Biology
05:38 - Conceptualizing Human Biology for Drug Interaction
06:25 - Understanding Emulation and Simulation
07:04 - The Role of Bacteria in Drug Efficacy
07:34 - The Distinction Between Emulation and Simulation
08:34 - NASA's Use of Emulation
09:10 - The Importance of Understanding Mechanisms in Medicine
09:43 - The Reality of Drug Response Rates
10:21 - BioCortex's Approach to AI and Emulation
11:01 - The Co-Founders' Meeting and Collaboration
11:29 - The Genesis of BioCortex
12:00 - Addressing Motor Neurone Disease Communication
13:02 - The Evolution of Nick and Mo's Partnership
13:38 - The Challenge of Modeling Bacteria
14:02 - The Solution to Modeling Complex Biological Systems
14:58 - The Importance of Trust in Co-Founder Relationships
16:01 - The Dynamics of Co-Founder and VC Relationships
16:53 - Defining Tech Bio vs. Biotech
17:36 - Capital Efficiency and Growth Concerns
18:11 - Maintaining Culture and Focus in a Startup
19:08 - The Challenge of Diverse Disciplines in a Tech Bio Team
20:00 - The Impact of Remote Work on Team Dynamics
21:19 - The Importance of Security and Tools for Remote Work
22:04 - The Benefits of In-Person and Remote Work Balance
22:44 - The Diverse Expertise within the BioCortex Team
00:23:27 - The Future of Tech Bio and Biotech Industry

In this episode of Nothing Ventured, host Aarish Shah interviews Renan
Devilliers, the founder of OSS Ventures, a startup studio focused on
revolutionizing operations in organizations providing physical services.
Renan shares insights from his journey, including founding Chance, a
successful recruitment tech business, and the challenges he faced along
the way. Tune in to hear about Renan's experiences at a Tesla factory,
navigating business pivots, and the critical role of operations in the
future of industries.

⏱️ Timestamps:
02:24 - Quick Fire Round with Renan
03:17 - OSS Ventures: Venture Builder Model
04:06 - Renan's Favorite Portfolio Companies
05:05 - Wine Preferences and Geographical Partisanship
05:35 - Renan's Journey and Departure from Chance
07:33 - Pivoting Business Model from Europe to Brazil
09:36 - Competitive Advantages of Different Countries
10:08 - OSS Ventures' Focus on Factory Operations
15:24 - Realization of Change in Manufacturing Space
18:03 - Sponsor Break: Emerge One
18:35 - Manufacturing Operations in the 21st Century
21:01 - Software's Role in Modern Manufacturing
23:39 - Personalized Medicine and Economic Value
24:43 - Trends in the Manufacturing and Operations Space
27:07 - Resilience as a Top CEO Priority
30:05 - Software Disruption in Textile Industry with Shein
32:07 - AI Trends in Physical Products and Processes
35:15 - Advice for Hardware Founders
36:56 - Sam Altman's Ambitious Funding Goals
37:44 - OSS Ventures' First Exit: Niagara Acquisition
38:49 - Closing Remarks and Contact Information