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In our news wrap Wednesday, the Food and Drug Administration reported Johnson & Johnson's COVID vaccine is 66-percent effective against moderate and severe symptoms, President Biden's attempt to halt most immigrant deportations for 100 days is on hold, and a former staffer for New York Gov. Andrew Cuomo escalates her claims of sexual assault. PBS NewsHour is supported by - https://www.pbs.org/newshour/about/funders

The West African country of Ghana on Wednesday became the first nation to receive a delivery of COVID-19 vaccines through a global initiative called COVAX, which aims to give more equitable access to the vaccine. Nick Schifrin reports and speaks to Dr. Nahid Bhadelia, medical director of the special pathogens unit at Boston Medical Center, to learn more about global inequities. PBS NewsHour is supported by - https://www.pbs.org/newshour/about/funders

As the 10-year anniversary of the civil war in Syria looms and fighting rages on in the hard-hit city of Idlib, Syria, doctors contending with the pandemic are stretched to their limits. In the last three months, COVID-19 infection rates in the Syrian opposition's final stronghold have increased more than 50 percent, while the virus has been targeting the most vulnerable. Ali Rogin reports. PBS NewsHour is supported by - https://www.pbs.org/newshour/about/funders

In our news wrap Tuesday, President Biden held the first bilateral meeting of his administration with Canadian Prime Minister Justin Trudeau, Biden's pick for U.N. ambassador was confirmed by the Senate, former Sen. David Perdue will not run for his old seat next year, U.N. nuclear inspectors confirmed Iran is enriching Uranium to 20% purity and Facebook agreed to lift a ban on Australian users. PBS NewsHour is supported by - https://www.pbs.org/newshour/about/funders

Europe's vaccination rollout is in crisis with manufacturing delays causing supply shortages and thousands of appointments cancelled indefinitely. The European Union wants to see 70 percent of its population inoculated by the fall. But frustration is growing amongst its citizens amid the realization those targets could be out of reach. Special Correspondent Lucy Hough reports. PBS NewsHour is supported by - https://www.pbs.org/newshour/about/funders

Britain's Prime Minister Boris Johnson has announced a cautious timetable ending the country's COVID lockdown, one of the strictest in the world with almost all foreign travel outlawed under the guidelines. But the full lockdown isn't due to finish until at least late June, while mental health issues are increasingly being amplified. Special correspondent Malcolm Brabant reports. PBS NewsHour is supported by - https://www.pbs.org/newshour/about/funders