Solving the Puzzle with Dr. Datis Kharrazian Datis Kharrazian, PhD, DHSc, DC, MS, MMSc, FACN

This episode explores the world of the immune system's response to pathogens and chronic infections. Dr. Kharrazian discusses the intricate mechanisms pathogens use to evade the immune system, leading to chronic infections and reactivations. He speaks on the impact of immune compromise, genetic factors, and other environmental influences on the severity of infections and autoimmune diseases. He also discusses the pivotal role of protein intake, the formation of antibodies, and the potential link between pathogen-induced inflammation and neurodegenerative diseases.
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For patient-oriented courses, visit https://drknews.com/online-courses/
For CE and CME practitioner courses, visit https://kharrazianinstitute.com/
00:00 Different pathogens have unique effects on health.
06:30 Local infection can trigger widespread systemic inflammation.
10:32 Chronic infections can reactivate and cause autoimmunity.
18:51 Pathogens can lead to Alzheimer's disease development.
24:38 Inflam aging causes inflammation and body pain.
27:47 Blood contains complement systems, T and B cells, and innate adaptive immunity. Persistent pathogens hide in tissues, evade immune barriers. Chronic infections indicate immune system issues.
33:02 Complement proteins indicate pathogenic load in blood.
40:40 Importance of proteins in immune system activation.
46:00 Genetics impacts response to viral infections.
49:28 Weakened immunity can cause severe cytokine storms.
55:02 Tick and pathogen invasion into tissues explained.
58:53 Micronutrient deficiencies can impact immune compromise significantly.
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In this episode, Dr. Datis Kharrazian discusses hormone disorders and their impact on puberty, perimenopause, menopause, and andropause. He discusses the onset of hormone-related issues, such as puberty and perimenopausal transition, and provides evidence-based strategies for addressing menstrual irregularities, hormone imbalances, adrenal function, and more. Dr. Kharrazian also delves into the effects of hormone replacement therapy (HRT), the role of essential fatty acids and seed oils, and the impacts of stress on hormone levels. Additionally, he answers questions on hormone therapy, hormone depletion, and the evaluation of pituitary tumors. Listeners will gain insights into managing hormone-related health conditions and understanding the complexities of the endocrine system.
Learn more at drknews.com
For patient-oriented courses, visit https://drknews.com/online-courses/
For CE and CME practitioner courses, visit https://kharrazianinstitute.com/
00:00 Addressing imbalances, electrolyte depletion, and functional medicine.
04:42 Underweight PCOS patients need specific health care.
07:17 Chart discussed general symptoms, diagnostic steps, treatment.
10:32 Analyze protein and fat intake for health.
15:30 Weight loss can release stored toxins and hormones.
18:29 Steroids and sleep, light, sound sensitivity strategies.
20:14 Perimenopausal insomnia and low testosterone concerns addressed.
23:31 Podcast content not a substitute for medical advice.
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In this episode, Dr. Kharrazian provides insights on growth hormone deficiency, testosterone replacement therapy, strategies for PCOS and infertility, and much more. From discussing the use of growth hormone stimulating peptides to addressing heavy menstrual bleeding and gallbladder issues, this episode offers evidence-based approaches to optimizing endocrine function.
Learn more at drknews.com
For patient-oriented courses, visit https://drknews.com/online-courses/
For CE and CME practitioner courses, visit https://kharrazianinstitute.com/
00:00 Gradual use of HRT therapy based on age.
08:27 Customized hormone therapy starts with low doses.
13:03 Testosterone therapy aids weight loss in men.
20:15 Testosterone replacement therapy may benefit men with diabetes.
23:10 Testosterone replacement therapy in men is safe.
30:20 Men with low testosterone treated with injections.
35:05 Managing testosterone levels in men, potential issues.
38:09 Dietary and lifestyle strategies impact hormones clinically.
48:13 Music therapy, blood sugar, ketogenic diet, sleep issues.
52:33 Nutraceuticals impact insulin resistance; fasting benefits.
56:09 Women in menopause may experience gallbladder issues.
01:03:26 Nutraceutical protocols, insulin signaling, PCOS treatment options.
01:10:20 Evaluate hypoglycemia, insulin resistance, and dietary history.
01:16:18 Decide on hormone therapy based on risks.
01:17:43 Understanding aging and its impact on health.
01:22:32 Podcast content not a substitute for medical advice.

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In this episode we dive into the intricate web of hormone imbalances, menstrual disorders, and andropause. We explore the impact of estrogen and progesterone imbalances on the menstrual cycle, as well as the role of prostaglandin imbalances in conditions like dysmenorrhea and PMS. We also uncover the complexities of andropause in males and address the various symptoms and treatment options available.
Learn more at drknews.com
For patient-oriented courses, visit https://drknews.com/online-courses/
For CE and CME practitioner courses, visit https://kharrazianinstitute.com
00:00 Female and male hormone transition patterns summarized.
08:51 BMI impacts endocrine system, genetic factors matter.
12:40 Excessive estrogen production causes gynecomastia in men.
18:51 Prostaglandins influence menstrual pain and discomfort.
26:21 Causes of heavy or light menstrual bleeding.
32:24 High DHE and testosterone levels suggest PCOS.
33:24 PCOS symptoms can normalize with metabolic control.
38:45 PCOS pathophysiology, treatment, and clinical manifestations.
45:19 Adrenal glands help manage perimenopausal symptoms.
49:33 Hormonal changes in perimenopause cause inflammatory response.
59:03 Inflammation and hormones affect women's health.
01:03:18 Menopause can worsen underlying health conditions.
01:06:44 Adulthood: decline in male function and symptoms.
01:13:49 LH levels range indicates potential hormone balance.
01:16:27 Free testosterone is crucial, especially as we age.
01:25:04 Normal range testosterone, relative hypogonad men, DHT.
01:27:26 Male and female hormone disorders patterns explained.

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In this episode, Dr. Kharrazian delves into the world of hormone imbalances, microbiome diversity, and the impact of polyphenols and phytoestrogens. He discusses evidence-based strategies for autoimmune disease, brain health issues, and chronic health conditions, and sheds light on the pivotal role of gut health in estrogen metabolism. He also addresses nutraceutical support for insulin resistance and regulating testosterone.
 
For patient-oriented courses, visit https://drknews.com/online-courses/
For CE and CME practitioner courses, visit https://kharrazianinstitute.com/
00:00 Transitioning off HRT may benefit from modulators.
06:05 Flavonoids affect estrogen receptor, 4 key foods.
10:05 Healthy microbiome diversity enhances effectiveness of soy products.
11:16 Carbs impact conversion of phytoestrogens efficiently.
16:29 Gut health crucial for managing estrogen disorders.
18:57 Diet, lifestyle, supplements affect microbiome diversity.
20:53 Liver pathways detoxifying hormones, potential competition. Nutrients aid hepatic inflammation support.
26:51 Essential fatty acids are critical for health.
30:29 Prostate glands cause pelvic issues, need support.
34:19 Men's testosterone, estrogen testing, insulin resistance, obesity, blood sugar imbalances, hypoglycemia, insulin resistance, dietary guidelines.
36:02 Optimize diet to prevent blood sugar crashes.
39:41 Review found herbal medicines improve PCOS symptoms.
42:41 Aggressive protocol for PCOS using nutraceuticals.
47:19 Nutraceuticals may protect serotonin cells, boost testosterone.
50:44 Botanicals boost testosterone levels but may vary.
53:42 Glial cells switch to pro-inflammatory state. Hormone changes amplify neuroinflammation.
56:35 Peptides stimulate hormones, potential for endocrine treatment.
58:37 Dr. Kharrazian's podcast and blog information.
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In this episode, Dr. Kharrazian provides insight into the impact of obesity on male and female hormone imbalances, infertility, and the body's endocrine system. From the role of adipose tissue to the effects of hormone replacement therapy, this episode explores the complexities of hormone balance and offers evidence-based strategies for managing these crucial aspects of health. Dr. Kharrazian discusses blood glucose management, gut health, and the impact of hormone deficiencies on mitochondrial function and other aspects of physiology.
For patient-oriented courses, visit https://drknews.com/online-courses/
For CE and CME practitioner courses, visit https://kharrazianinstitute.com/
Learn more at drknews.com
Timestamps:
00:00 Hormones impact mitochondria, affecting cellular function.
09:31 Mitochondrial health affects recovery and signaling pathways.
12:00 Hormone replacement may fix mitochondrial dysfunction. Stress affects mitochondria.
16:22 Certain genetic factors can increase health risks.
25:26 Aromatization causes body fat increase, vicious cycle.
31:00 Estrogen drop in women leads to fat tissue.
32:52 Steroid use can disrupt endocrine system balance.
42:35 Healthy adrenal function is crucial in perimenopause.
48:03 Adrenal gland imbalances and stress responses summarized.
53:04 Insulin resistance causes blood sugar roller coaster.
57:10 Symptom patterns indicating early stages of insulin resistance.
01:02:30 Gut bacteria convert chemicals and hormones.
01:08:19 Hormone deficiency causes leaky gut, affecting health.
01:12:26 Inflammatory diets cause low testosterone levels.
01:20:18 Hormones critical for health and disease prevention.
01:23:28 Hormone imbalances affect brain recovery and health.
01:28:20 For more info visit drknews.com/podcast.
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