9 episodios

Vaccines save millions of lives each year; however, some of the world's worst diseases are still difficult to prevent. Our series of podcasts on Epidemics and Vaccines detail the research within NDM to combat diseases such as hepatitis, influenza and tuberculosis, through development of novel vaccines and vaccine delivery mechanisms and strategies. Developing countries and vulnerable populations are a particular focus of some of this work.

Epidemics and Vaccines Oxford University

    • Cursos

Vaccines save millions of lives each year; however, some of the world's worst diseases are still difficult to prevent. Our series of podcasts on Epidemics and Vaccines detail the research within NDM to combat diseases such as hepatitis, influenza and tuberculosis, through development of novel vaccines and vaccine delivery mechanisms and strategies. Developing countries and vulnerable populations are a particular focus of some of this work.

    Emerging Infectious Diseases

    Emerging Infectious Diseases

    Professor Peter Horby is Senior Clinical Research Fellow. His research focusses on epidemic diseases such as Ebola and bird flu, and crosses the disciplines of basic science, medical science and public health. Influenza, SARS & Ebola

    Research on emerging infectious diseases can only be conducted during outbreaks. Although virology has improved, a well calibrated and effective public health response is often lacking. Epidemiological and clinical research as well as mathematical modelling will give us answers during the epidemics and help us provide better diagnostics and better treatments. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

    • 6 min
    Structural biology and vaccines

    Structural biology and vaccines

    Structure of viruses Professor David Stuart studies the structure of viruses at the molecular level. His work is particularly interested in virus-receptor interaction and the basic puzzles of virus assembly and he uses structural biology to answer these questions. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

    • 7 min
    Viruses, how to be the perfect host

    Viruses, how to be the perfect host

    Professor Paul Klenerman talks about our relationship with persistent viruses, such as Hepatitis C. Hepatitis C virus infects around 200 million people worldwide and is a major cause of liver disease. Understanding immune responses to the virus could help to protect or cure people with Hepatitis C. Professor Paul Klenerman studies relationships between persistent viruses such as Hepatitis C and their human hosts. Professor Klenerman aims to understand the role of our immune responses in determining the outcome of Hepatitis C virus infection. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

    • 4 min
    Hepatitis C vaccine

    Hepatitis C vaccine

    Dr Ellie Barnes talks about her research on Hepatitis C and her work on a T cell vaccine. Hepatitis C virus is a global epidemic, affecting around 200 million people worldwide. Many chronically infected patients silently develop complications of liver disease that can include hepatocellular cancer, liver cirrhosis and liver failure. Unlike other vaccines, inducing antibody reactions to Hepatitis C is often ineffective because antibodies only target the outer surface of the virus. To combat this Dr Ellie Barnes is developing a new therapeutic vaccine for this damaging virus. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

    • 5 min
    Universal Flu Vaccine

    Universal Flu Vaccine

    Dr Richard Antrobus talks about his research in the development of a universal flu vaccines. Universal flu vaccines target specific parts of the influenza virus that stay relatively stable between different strains of flu. Dr Richard Antrobus is conducting a Phase I study for a universal influenza vaccine. Progress so far indicates that this approach induces a potent T cell response, and Dr Antrobus is assessing whether this response is equally potent in the elderly - one of the 'at risk' groups of the influenza virus. If successful this vaccine will protect against a wide range of strains of the virus. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

    • 6 min
    Viral vectored vaccine development

    Viral vectored vaccine development

    Professor Sarah Gilbert talks about her work on viral vectored vaccines. Viral vectored vaccines combine a safe virus with a disease protein to protect against specific diseases. These vaccines have the potential to drastically improve public health. Professor Sarah Gilbert has been making and testing vaccines designed to induce T cell responses for ten years, chiefly using antigens from malaria and influenza. Based at the Jenner Institute, several of the vaccines developed in Professor Gilbert's laboratory have progressed into clinical trials. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

    • 3 min

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