1h 16 min
Targeting Senescent Cells? Dose and Timing Matters - with Dr. Greg Kelly Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics
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- Salud y forma física
Get ready for a deep dive into the world of cellular senescence and its implications for aging. Dr. Greg Kelly joins me on New Frontiers to explain the science behind targeting this Hallmark of Aging and share natural compounds and activities that target cellular senescence. I am particularly excited for you to hear his thoughts around dosing and cyclical timing of exposure to senolytic compounds, such as fisetin, luteolin, quercetin, and piperlongumine, and why that may make the difference between having the effect you want... or not. Don't miss his advice on smart exercise tweaks for aging and the caution that overdoing it with exercise in our later years is much more harmful than it was in our twenties. Lots to unpack here. Enjoy! - DrKF
Head over to https://www.drkarafitzgerald.com/fxmed-podcast/ for all the full transcription and all relevant links and resources.
Guest information
Dr. Greg Kelly is Senior Director of Product Development at Neurohacker Collective, naturopathic physician (N.D.), and author of the book Shape Shift.
Email: greg@neurohacker.com
Facebook: https://www.facebook.com/neurohackercollective
Instagram: https://www.instagram.com/neurohacker/
LinkedIn: https://www.linkedin.com/in/gregory-kelly-98b96b138/
Qualia Discount for New Frontiers Listeners
If you’re in your late 20’s or older, adding Qualia Senolytic to your diet can play a CRUCIAL role in combating negative aging symptoms. Go to https://tinyurl.com/3zpsaw3s for up to 50% off Qualia Senolytic and as a listener of New Frontiers podcast use code KARA at checkout for an extra 15% off your first purchase.
Show Notes
Dr. Gregory Kelly: https://neurohacker.com/people/greg-kelly
Neurohacker Collective: https://tinyurl.com/3zpsaw3s
Shape Shift: https://tinyurl.com/3zpsaw3s
Alternative Medicine Review: https://tinyurl.com/56ad9av9
OMEMI Trial - https://pubmed.ncbi.nlm.nih.gov/33191772/
REDUCE-IT Study - https://clinicaltrials.gov/study/NCT01492361
ASCEND Study - https://ascend.medsci.ox.ac.uk
VITAL Study - https://www.vitalstudy.org/
Longitudinal Study - Multi-omics Biological Age Estimation and Its Correlation with Wellness and Disease Phenotypes - https://tinyurl.com/2p85yx5f
DrKF Resources
Patient consults with DrKF physicians including Younger You Concierge: https://www.drkarafitzgerald.com/our-clinic/our-services/
Bio Age Lab Test: https://youngeryouprogram.com/bio-age-lab-test/
Bio Age Self Assessment Quiz: https://youngeryouprogram.com/basa/
Younger You Group Program: https://www.drkarafitzgerald.com/younger-you-intensive-virtual-group/
Younger You book: https://youngeryouprogram.com/book/
Get ready for a deep dive into the world of cellular senescence and its implications for aging. Dr. Greg Kelly joins me on New Frontiers to explain the science behind targeting this Hallmark of Aging and share natural compounds and activities that target cellular senescence. I am particularly excited for you to hear his thoughts around dosing and cyclical timing of exposure to senolytic compounds, such as fisetin, luteolin, quercetin, and piperlongumine, and why that may make the difference between having the effect you want... or not. Don't miss his advice on smart exercise tweaks for aging and the caution that overdoing it with exercise in our later years is much more harmful than it was in our twenties. Lots to unpack here. Enjoy! - DrKF
Head over to https://www.drkarafitzgerald.com/fxmed-podcast/ for all the full transcription and all relevant links and resources.
Guest information
Dr. Greg Kelly is Senior Director of Product Development at Neurohacker Collective, naturopathic physician (N.D.), and author of the book Shape Shift.
Email: greg@neurohacker.com
Facebook: https://www.facebook.com/neurohackercollective
Instagram: https://www.instagram.com/neurohacker/
LinkedIn: https://www.linkedin.com/in/gregory-kelly-98b96b138/
Qualia Discount for New Frontiers Listeners
If you’re in your late 20’s or older, adding Qualia Senolytic to your diet can play a CRUCIAL role in combating negative aging symptoms. Go to https://tinyurl.com/3zpsaw3s for up to 50% off Qualia Senolytic and as a listener of New Frontiers podcast use code KARA at checkout for an extra 15% off your first purchase.
Show Notes
Dr. Gregory Kelly: https://neurohacker.com/people/greg-kelly
Neurohacker Collective: https://tinyurl.com/3zpsaw3s
Shape Shift: https://tinyurl.com/3zpsaw3s
Alternative Medicine Review: https://tinyurl.com/56ad9av9
OMEMI Trial - https://pubmed.ncbi.nlm.nih.gov/33191772/
REDUCE-IT Study - https://clinicaltrials.gov/study/NCT01492361
ASCEND Study - https://ascend.medsci.ox.ac.uk
VITAL Study - https://www.vitalstudy.org/
Longitudinal Study - Multi-omics Biological Age Estimation and Its Correlation with Wellness and Disease Phenotypes - https://tinyurl.com/2p85yx5f
DrKF Resources
Patient consults with DrKF physicians including Younger You Concierge: https://www.drkarafitzgerald.com/our-clinic/our-services/
Bio Age Lab Test: https://youngeryouprogram.com/bio-age-lab-test/
Bio Age Self Assessment Quiz: https://youngeryouprogram.com/basa/
Younger You Group Program: https://www.drkarafitzgerald.com/younger-you-intensive-virtual-group/
Younger You book: https://youngeryouprogram.com/book/
1h 16 min