Pioneering Precision: Kira Dineen on Genetics' Role in Tailored Therapies RealPharma: Conversations with Pharma Pathfinders

Summary
In this episode, hosts Ian Wendt and Dr. Na-Ri Oh , and guest Kira Dineen discuss the intersection of genomics and healthcare. They explore the concept of personalized medicine and how advancements in genomics are revolutionizing healthcare. Kira shares her personal journey and the inspiration behind her DNA Today podcast. The conversation delves into the technology behind personalized medicine and the challenges of building comprehensive genetic databases. The ethical considerations of genomics, including access to information and the potential misuse of genetic data, are also explored. The episode concludes with a discussion on the need for ethical frameworks to keep pace with technological advancements in genomics. The conversation explores the controversial topic of gene editing, particularly the use of CRISPR technology. The hosts discuss the ethical considerations and the choice of genetic targets for editing. They also touch on the accessibility and long-term consequences of CRISPR. The conversation then shifts to the cost of treatment and the role of genetic testing in drug development. The potential of AI in genetic research is explored, as well as the future of personalized medicine. The episode concludes with a discussion on professional motivation and the importance of networking.

Chapters
00:00 Introduction to Kira Dineen and the Intersection of Genomics and Healthcare
02:07 Genomics and Personalized Medicine
04:13 Kira Dineen's Personal Journey and the DNA Today Podcast
08:08 The Trend Towards Personalized Medicine in Biopharma
10:11 The Technology Behind Personalized Medicine
12:39 Building Databases and Overcoming Barriers
15:18 Ethical Considerations in Genomics
20:39 Ethics and the Use of Genetic Information
24:06 Ethics Keeping Pace with Technological Advances
25:44 Managing Ethical Considerations in Genetic Research
27:21 Controversial Gene Editing
28:18 Choosing Genetic Targets
29:10 Ethical Considerations
29:44 Accessibility of CRISPR
30:13 Long-Term Consequences of CRISPR
32:51 Healthcare Equity and Cost of Treatment
34:25 Cost of Genomic Sequencing
35:22 Genetic Testing and Drug Development
38:13 Role of Genetic Testing in Clinical Trials
42:20 AI in Genetic Research
46:34 Future of Personalized Medicine
49:56 Professional Motivation and Networking

Resources:
Kira Dineen, MS, LCGC, CG(ASCP)CM (LInkedIn, Twitter)DNAtoday.comBreath from Salt (DNA Today author interview Episode #147)Maury Povich interview on DNA Today Patient Empowerment Program: A Rare Disease Podcast