RealPharma: Conversations with Pharma Pathfinders RealPharma

Summary
In this episode, Kristiaan Rawlings discusses the 2024-2025 Commercial Market Update and Salary Guide produced by EPM Scientific. The life sciences sector remains resilient due to aging populations, scientific advances, and robust investment. Hiring practices and compensation are influenced by these factors across the Americas, Europe, and APAC regions. The hiring focus has shifted from life-threatening diseases to more common health issues, such as dermatology and respiratory diseases. The most in-demand roles include marketing, commercial operations (salesforce effectiveness, commercial analytics, and training), and sales. Market access roles have seen less demand. Despite the availability of talent, salaries have remained high or even increased. In this conversation, Kristiaan Rawlings discusses the current trends in the life sciences job market, specifically in the commercial operations field. He explains the increase in demand for talent, the impact of title deflation, and the rise in salaries. He also highlights the regional differences in job opportunities, with a shift towards the East Coast of the United States. Additionally, he touches on the importance of executive presence and the return of in-person networking events. Overall, the conversation provides valuable insights into the evolving landscape of the life sciences job market.

Chapters
00:00 High Demand for Marketing Roles
04:26 Focus on Core Areas with Existing Blockbuster Products
05:53 Sought-After Skills for Commercial Operations and Product Launches
13:54 Challenges with LinkedIn Applications and Fake Job Postings
24:25 Selective Market Based on Therapy Area and Experience
24:51 The Three Pillars of Focus: Salesforce Effectiveness, Commercial Analytics, and Training
25:21 High Demand for Talent in Incentive Compensation, Analytics, and Competitive Intelligence
26:17 Sales Roles in High Demand During Product Launches
26:46 Quiet Market in the Field of Market Access
27:14 Salaries Holding Strong or Increasing Despite High Supply of Talent
32:30 Geography Becoming Less of a Factor in Salary and Opportunity
41:08 High Demand for Medical Affairs and Health Economics
44:01 The Importance of Executive Presence and Networking for Career Success

Resources
Kristiaan Rawlings - LinkedIn
2024/2025 EPM Commercial Update and Salary Guide

Summary
In this episode, hosts Ian Wendt and Dr. Na-Ri Oh , and guest Kira Dineen discuss the intersection of genomics and healthcare. They explore the concept of personalized medicine and how advancements in genomics are revolutionizing healthcare. Kira shares her personal journey and the inspiration behind her DNA Today podcast. The conversation delves into the technology behind personalized medicine and the challenges of building comprehensive genetic databases. The ethical considerations of genomics, including access to information and the potential misuse of genetic data, are also explored. The episode concludes with a discussion on the need for ethical frameworks to keep pace with technological advancements in genomics. The conversation explores the controversial topic of gene editing, particularly the use of CRISPR technology. The hosts discuss the ethical considerations and the choice of genetic targets for editing. They also touch on the accessibility and long-term consequences of CRISPR. The conversation then shifts to the cost of treatment and the role of genetic testing in drug development. The potential of AI in genetic research is explored, as well as the future of personalized medicine. The episode concludes with a discussion on professional motivation and the importance of networking.

Chapters
00:00 Introduction to Kira Dineen and the Intersection of Genomics and Healthcare
02:07 Genomics and Personalized Medicine
04:13 Kira Dineen's Personal Journey and the DNA Today Podcast
08:08 The Trend Towards Personalized Medicine in Biopharma
10:11 The Technology Behind Personalized Medicine
12:39 Building Databases and Overcoming Barriers
15:18 Ethical Considerations in Genomics
20:39 Ethics and the Use of Genetic Information
24:06 Ethics Keeping Pace with Technological Advances
25:44 Managing Ethical Considerations in Genetic Research
27:21 Controversial Gene Editing
28:18 Choosing Genetic Targets
29:10 Ethical Considerations
29:44 Accessibility of CRISPR
30:13 Long-Term Consequences of CRISPR
32:51 Healthcare Equity and Cost of Treatment
34:25 Cost of Genomic Sequencing
35:22 Genetic Testing and Drug Development
38:13 Role of Genetic Testing in Clinical Trials
42:20 AI in Genetic Research
46:34 Future of Personalized Medicine
49:56 Professional Motivation and Networking

Resources:
Kira Dineen, MS, LCGC, CG(ASCP)CM (LInkedIn, Twitter)DNAtoday.comBreath from Salt (DNA Today author interview Episode #147)Maury Povich interview on DNA Today Patient Empowerment Program: A Rare Disease Podcast 

Dive into the high-stakes world of Venture Capital in biopharma with Jim Trenkle! Have you ever wondered what it takes to turn groundbreaking scientific discoveries into life-saving treatments? What role do venture capitalists play in this thrilling journey from the lab to the clinic? This episode peels back the curtain on the biopharma venture capital scene, revealing the risks, rewards, and radical innovations driving the future of healthcare. Join hosts Dr. Na-Ri Oh and Ian Wendt as they explore with Jim the secrets of successful biopharma investments, the challenges of navigating the complex landscape of medical research funding, and the thrilling potential of the next big breakthroughs. Don't miss this conversation that could change the way you see medicine and innovation.

In this episode, Jim Trenkle, a partner at Nova Holdings, shares insights on venture capital in the biopharma industry. He explains the different stages of investment, from seed rounds to IPOs, and the role of venture capitalists in providing capital and expertise.

Jim discusses the current state of raising capital for biotech startups, including the impact of interest rates and market conditions. He also highlights the challenges and evaluation criteria in biotech VC, emphasizing the importance of a well-thought-out plan and addressing unmet needs. Additionally, Jim discusses hot areas and trends in biotech investing and shares his atypical career path.

Jim Trenkle also discusses his own career path and the importance of finding work that has a deeper impact. He shares his journey from being a medicinal chemist to venture capital, highlighting the value of lifelong learning and broadening one's impact. Trenkle also discusses the challenges and skills required in venture capital, emphasizing the need for humility and the ability to make decisions that have a real impact. He reflects on the lessons learned from the Theranos scandal and the role of venture capitalists in evaluating companies.

Trenkle explores the reasons behind company closures and failures in the biopharma industry and the potential for innovation and technological advances to shape the future of venture capital. He concludes with advice on career growth and the importance of following one's passion.


Chapters
00:00 Introduction of Jim Trankel

01:01 Understanding Venture Capital in BioPharma

07:59 The Current State of Raising Capital for Biotech startups

11:23 The Landscape of Biotech Funding

16:25 Challenges and Evaluation in Biotech VC

23:16 What Does Good Look Like and Pitfalls to Avoid

31:19 Jim Trankel's Career Path

31:59 Career Path and Impact

35:19 Challenges and Skills in Venture

37:05 Evaluating Companies and Capital Allocators

38:23 Lessons from Theranos

46:01 Company Closures and Failures

52:42 The Future of VC in Biopharma

58:32 Advice and Mentors

Join us on a deep dive into the world of Health Economics and Outcomes Research (HEOR) with the remarkable Iris Tam, PharmD, a luminary in value-based evidence generation within the biopharma industry. In this episode, our hosts Ian and Na-Ri explore with Iris the critical role of HEOR in transforming today's pharmaceutical landscape, from drug development to global marketing strategies and beyond.

Unpacking the complexities of HEOR, they delve into its definition, significance, and the evolving importance of this field in aligning drug development with payer expectations and patient outcomes. Iris shares invaluable insights on the key elements that payers scrutinize in HEOR studies, and the strategic considerations essential for successful global product launches.

Ethical considerations in HEOR research also take center stage, highlighting the responsibility of ensuring integrity and patient-centricity in evidence generation. For professionals eager to make their mark in HEOR or advance their careers, Iris offers sage advice, emphasizing the need for robust data, the value of learning from post-mortems, and the art of using failures to forge successful future strategies.

This episode is not just an exploration of HEOR's impact on healthcare but a guide to understanding the challenges of demonstrating product value and the crucial role of user adoption. Whether you're a seasoned professional or new to the field, Iris's journey and insights offer inspiration and guidance for navigating the complexities of HEOR in the biopharma industry.

Chapters
00:00 Introduction of Iris Tam

02:08 Definition and Significance of HEOR

04:07 Evolution and Increasing Role of HEOR

07:49 Components of HEOR: Health Economics and Outcomes Research

10:26 Impact of HEOR on Drug Development and Marketing Strategies

25:46 Key Elements for Payers in HUR Studies

38:47 Considerations for HUR in Global Launches

41:35 Ethical Considerations in HUR Research

46:41 Skills and Experiences for Success in HUR

51:49 The importance of user adoption

52:01 Learning from post mortems

53:01 Using failures to inform future strategies

53:55 The challenge of proving product benefits

54:23 Closing thoughts and advice

Dive into the world of fertility with Shelley Bailey, the visionary founder and CEO of Famlee Fertility, on our latest episode. Discover Shelley's personal journey that led to the creation of Famlee, a company revolutionizing the fertility landscape with its home-based testing and clinical treatments aimed at empowering women to understand and enhance their fertility.

In this enlightening conversation, Shelley unravels the role of Famlee in supporting women through their fertility treatment journey, debunking common myths and misconceptions that surround fertility. Learn about the holistic approach and tailored treatment plans Famlee offers, designed to balance hormones and improve fertility from the comfort of home.

Tune in to gain valuable insights into overcoming fertility challenges, the importance of personalized care, and the future of fertility treatments. Whether you're navigating your own fertility journey or simply interested in the innovations transforming women's health, this episode promises to enlighten, inspire, and empower.

Chapters:
00:00 Introduction to Shelley Bailey and Famlee Fertility

04:02 Shelley's Personal Journey and Inspiration for Starting Famlee

09:47 The Role of Famlee in the Fertility Treatment Journey

14:38 Positioning Famlee in the Healthcare Landscape

17:10 Common Myths and Misconceptions about Female and Male Fertility

23:39 The Journey with Famlee: Holistic Approach and Treatment Plan

32:47 Challenges Faced as a Founder in the Fertility Sector

42:15 Future Plans and Expansion for Famlee

43:49 Mentors and Inspiration in Shelley's Entrepreneurial Journey

Dr. Jerome Adams, the 20th US Surgeon General, discusses various topics related to public health, including Operation Warp Speed, diversity in clinical trials, improving healthcare access and outcomes, addressing health inequities, collaborative approaches in healthcare, challenges with pricing models, the importance of prevention and health literacy, and lessons learned from COVID-19.

In this conversation, Dr. Jerome Adams discusses the impact of political pandering on public health messaging and the erosion of trust in the CDC. He emphasizes the need for proper funding and communication in the CDC to effectively respond to public health crises. Dr. Adams also highlights the importance of practical information and listening to the public, as well as supporting public health workers. He suggests protecting the independence of CDC directors and Surgeon Generals to instill trust in the organization.

The conversation also touches on the reputation of the pharma industry and the paradox of trust and distrust in public health organizations. Dr. Adams concludes by sharing his guiding principles of caring and finding common ground.

Chapters
00:00 Introduction to Dr. Jerome Adams
02:18 Discussion on Operation Warp Speed
05:34 Importance of Diversity in Clinical Trials
09:52 Improving Healthcare Access and Outcomes
18:03 Addressing Health Inequities
23:35 Collaborative Approach in Healthcare
25:30 Challenges with Pricing Models
30:21 Importance of Prevention and Health Literacy
35:06 Lessons Learned from COVID-19
45:57 The Impact of Political Pandering
46:53 The Perception of Political Leanings
47:40 The Erosion of Trust in the CDC
49:27 The Need for Proper Funding and Communication in the CDC
51:51 The Importance of Practical Information and Listening to the Public
53:25 The Importance of Supporting Public Health Workers
54:16 Protecting the Independence of CDC Directors and Surgeon Generals
55:47 The Reputation of the Pharma Industry
58:12 The Paradox of Trust and Distrust in Public Health Organizations
01:04:07 Guiding Principles: Caring and Finding Common Ground