16 min
Hunger Winter: Famine and The Foetal Origins of Disease Anamnesis: A Medical History
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- Science
Between the end of 1944 and may of 1945, the Third Reich imposed a devastating embargo on food into the German Occupied Netherlands. The resulting famine killed around 18,000 people. I have been talking to Dr Mandy Drake about how studies on the victims, in particular those who were exposed to the famine whilst in the womb, have given scientists a great insight into the importance of early foetal experiences on health in later life.
The Dutch Famine https://en.wikipedia.org/wiki/Dutch_famine_of_1944–45
Dutch Famine Cohort Study
https://academic.oup.com/ije/article/36/6/1196/814573/Cohort-Profile-The-Dutch-Hunger-Winter-Families
The Barker Hypothesis
Further reading: https://www.ncbi.nlm.nih.gov/pubmed/7613432
https://www.ncbi.nlm.nih.gov/pubmed/17444880
A reasonable article on the basics of epigenetics: https://www.theguardian.com/science/occams-corner/2014/apr/25/epigenetics-beginners-guide-to-everything
A good videoon molecular machines by Veritasium:
https://youtu.be/X_tYrnv_o6A
More about Dr Drake and her research: http://www.crh.ed.ac.uk/clah/dr-amanda-drake/
Between the end of 1944 and may of 1945, the Third Reich imposed a devastating embargo on food into the German Occupied Netherlands. The resulting famine killed around 18,000 people. I have been talking to Dr Mandy Drake about how studies on the victims, in particular those who were exposed to the famine whilst in the womb, have given scientists a great insight into the importance of early foetal experiences on health in later life.
The Dutch Famine https://en.wikipedia.org/wiki/Dutch_famine_of_1944–45
Dutch Famine Cohort Study
https://academic.oup.com/ije/article/36/6/1196/814573/Cohort-Profile-The-Dutch-Hunger-Winter-Families
The Barker Hypothesis
Further reading: https://www.ncbi.nlm.nih.gov/pubmed/7613432
https://www.ncbi.nlm.nih.gov/pubmed/17444880
A reasonable article on the basics of epigenetics: https://www.theguardian.com/science/occams-corner/2014/apr/25/epigenetics-beginners-guide-to-everything
A good videoon molecular machines by Veritasium:
https://youtu.be/X_tYrnv_o6A
More about Dr Drake and her research: http://www.crh.ed.ac.uk/clah/dr-amanda-drake/
16 min