Discover CircRes Cynthia St. Hilaire, PhD & Milka Koupenova, PhD

This month on Episode 59 of Discover CircRes, host Cindy St. Hilaire highlights original research articles featured in the April 12 and April 26th issues of Circulation Research. This Episode also includes a discussion with Dr Craig Morrell and Chen Li from University of Rochester about their study, Thrombocytopenia Independently Leads to Changes in Monocyte Immune Function.
Article highlights:
Arkelius, et al. LOX-1 and MMP-9 Inhibition Improves Stroke Outcomes
Cruz, et al. C122Y Disrupts Kir2.1-PIP2 Interaction in ATS1
Blaustein, et al. Environmental Impacts on Cardiovascular Health and Biology: An Overview

This month on Episode 58 of Discover CircRes, host Cynthia St. Hilaire highlights three original research articles featured in the March 1 and March 15th issues of Circulation Research. This Episode also includes a discussion with Drs Frank Faraci, Tami Martino, and Martin Young about their contributions to the Compendium on Circadian Mechanisms in Cardiovascular and Cerebrovascular Disease.
Article highlights:
Yan, et al. GCN2 in Ponatinib-Induced Cardiotoxicity
Wang, et al. Activating v-ATPase Ameliorates Cardiac Cardiomyopathy

This month on Episode 57 of Discover CircRes, host Cynthia St. Hilaire highlights three original research articles featured in the February 2nd and February 19th issues of Circulation Research. This Episode also includes a discussion with Dr Kathryn Howe and Dr Sneha Raju from University of Toronto, about their manuscript titled Directional Endothelial Communication by Polarized Extracellular Vesicle Release.
 
Article highlights:
Ren, et al. ZBTB20 Regulates Cardiac Contractility
Faleeva, et al. Sox9 Regulates Vascular Extracellular Matrix Aging
Bai, et al. PKA Is Critical for Cardiac Growth
Wang, et al. Indole-3-Propionic Acid Protects Against HFpEF

This month on Episode 56 of Discover CircRes, host Cynthia St. Hilaire highlights three original research articles featured in the January 5th and January 19th issues of Circulation Research. This Episode also includes a discussion with Dr Julie Freed and Gopika Senthilkumar from the Medical College of Wisconsin about their study, Necessary Role of Ceramides in the Human Microvascular Endothelium During Health and Disease.
 
Article highlights:
He, et al. T Cell LGMN Deficiency Prevents Hypertension
Salyer, et al. TnI-Y26 Phosphorylation Improves Relaxation
Jacob, et al. MFN2 in Megakaryocyte and Platelet Function

This month on Episode 55 of Discover CircRes, host Cynthia St. Hilaireaire highlights two original research articles featured in the December 8th issue of Circulation Research. This Episode also includes a discussion with Dr José Luis de la Pompa and Dr Luis Luna-Zurita from the National Center for Cardiovascular Research in Spain about their study, Cooperative Response to Endocardial NOTCH Reveals Interaction With Hippo Pathway.
 
Article highlights:
Shi, et al. Nat10 Mediated ac4C in Cardiac Remodeling
Knight, et al. CDK4 Oxidation Attenuates Cell Proliferation

This month on Episode 54 of Discover CircRes, host Cynthia St. Hilaire highlights three original research articles featured in the October 27th and November 10th issues of Circulation Research. This Episode also includes a discussion with Dr Sophie Susen and Dr Caterina Casari about their study, Shear Forces Induced Platelet Clearance Is a New Mechanism of Thrombocytopenia, published in the October 27th issue.
 
Article highlights:
Pass, et al. Single Nuclei Transcriptome of PAD Muscle
Liu, et al. Myocardial Recovery in DCM: CDCP1 and Fibrosis
Grego-Bessa, et al. Neuregulin-1 Regulates Chamber Morphogenesis
Agrawal, et al. A New Model of PH due to HFpEF