25 min

PDCD... Easy as 1, 2, 3‪!‬ The Clinical Concepts Podcast

    • Medicine

"Respond to a private residence for a 2-year-old female with an altered mental status, history of PDCD" A history of what? You know... PDCD! During this episode we explore Pyruvate Dehydrogenase Complex Deficiency, or PDCD. PDCD is a genetic abnormality which affects the conversion of pyruvate to Acetyl Coenzyme-A in the Krebs Cycle. This abnormality prevents mitochondrial energy utilization, leading to neurological degeneration. Join me as we take a dive into the EMS managemen...

"Respond to a private residence for a 2-year-old female with an altered mental status, history of PDCD" A history of what? You know... PDCD! During this episode we explore Pyruvate Dehydrogenase Complex Deficiency, or PDCD. PDCD is a genetic abnormality which affects the conversion of pyruvate to Acetyl Coenzyme-A in the Krebs Cycle. This abnormality prevents mitochondrial energy utilization, leading to neurological degeneration. Join me as we take a dive into the EMS managemen...

25 min