23 episodes

The focus of the MCG Pediatric Podcast is to produce educational material on pediatric general and subspecialty topics that will be helpful in everyday clinical practice. These discussions will be led by our pediatric residents with a general or subspecialty faculty member who is an expert in the field.

The MCG Pediatric Podcas‪t‬ mcgpediatricpodcast

    • Science
    • 5.0 • 21 Ratings

The focus of the MCG Pediatric Podcast is to produce educational material on pediatric general and subspecialty topics that will be helpful in everyday clinical practice. These discussions will be led by our pediatric residents with a general or subspecialty faculty member who is an expert in the field.

    Multisystem Inflammatory Syndrome in Children (MIS-C)

    Multisystem Inflammatory Syndrome in Children (MIS-C)

    TITLE: Multisystem Inflammatory Disease in Children (MIS-C)
    Last Updated: January 22, 2021
    PARTICIPANTS:
    Hosts: Sonal Dugar, Zachary Hodges, Pushpa Shivaram, Julisa Patel
    Peer Reviewer #1: Smitha Mathew
    Peer Reviewer #2: Reda Bassali
    By the end of listening to this podcast, learners should be able to:
    Recognize the general clinical presentation of MIS-C.
    Create a differential diagnosis for children presenting with a non-specific hyperinflammatory syndrome.
    Recall the CDC case definition of MIS-C.
    Recall the general approach to the initial evaluation of a patient with possible MIS-C.
    Compare and contrast the general presentation of MIS-C and Kawasaki disease.
    Recall the initial treatment of MIS-C including supportive care, IVIG and corticosteroids.
    Recall that anakinra and other immunomodulating drugs may be indicated for refractory MIS-C.
    Recognize that aspirin and anticoagulation may be indicated in severe cases of MIS-C.
    Recall the follow-up required for children with moderate to severe COVID-19 and MIS-C prior to return to normal activities.
    Thank you for listening to this episode from the Department of Pediatrics at the Medical College of Georgia.
    If you have any comments, suggestions, or feedback- you can email us at mcgpediatricpodcast@augusta.edu
    Visit our website at https://www.augusta.edu/mcg/pediatrics/residency/podcast.php for more information and show-notes.
    Remember that all content during this episode is intended for informational and educational purposes only.  It should not be used as medical advice to diagnose or treat any particular patient. Clinical vignette cases presented are based on hypothetical patient scenarios. We look forward to speaking to you on our next episode of the MCG Pediatric Podcast.  
     
    References:
    Godfred-Cato S, Bryant B, Leung J, et al. COVID-19–Associated Multisystem Inflammatory Syndrome in Children — United States, March–July 2020. MMWR Morb Mortal Wkly Rep 2020;69:1074–1080. DOI: http://dx.doi.org/10.15585/mmwr.mm6932e2external icon
    Riphagen S, Gomez X, Gonzalez-Martinez C, Wilkinson N, Theocharis P. Hyperinflammatory shock in children during COVID-19 pandemic. Lancet 2020;395:1607–8.
    Dufort EM, Koumans EH, Chow EJ, et al.; New York State and CDC Multisystem Inflammatory Syndrome in Children Investigation Team. Multisystem inflammatory syndrome in children in New York State. N Engl J Med 2020;383:347–58.
    Feldstein LR, Rose EB, Horwitz SM, et al. Multisystem Inflammatory Syndrome in U.S. Children and Adolescents. N Engl J Med. 2020;383(4):334-346. doi:10.1056/NEJMoa2021680
    Whittaker E, Bamford A, Kenny J, et al.; PIMS-TS Study Group and EUCLIDS and PERFORM Consortia. Clinical characteristics of 58 children with a pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2. JAMA 2020;324:259–69.
    Henderson LA, Canna SW, Friedman KG, Gorelik M, Lapidus SK, Bassiri H, et al. American College of Rheumatology Clinical Guidance for Pediatric Patients with Multisystem Inflammatory Syndrome in Children (MIS‐C) Associated with SARS‐CoV‐2 and Hyperinflammation in COVID‐19. Version 1. Arthritis Rheumatol doi: https://onlinelibrary.wiley.com/doi/10.1002/art.41454.
    Abrams JY, Godfred-Cato SE, Oster ME, Chow EJ, Koumans EH, Bryant B, Leung JW, Belay ED, Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with SARS-CoV-2: A Systematic Review, The Journal of Pediatrics (2020), doi: https://doi.org/10.1016/jpeds.2020.08.003.
    1161.CIRCULATIONAHA.120.049836. Review of Cardiac Involvement in MISC. Circulation
    Kaushik, Ashlesha MD*; Gupta, Sandeep MD†; Sood, Mangla MD‡; Sharma, Seema MD§; Verma, Shikha MD§ A Systematic Review of Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 Infection, The Pediatric Infectious Disease Journal: November 2020 - Volume 39 - Issue 11 - p e340-e346 doi: 10.1097/INF.00000000000028

    • 28 min
    One Pill Can Kill

    One Pill Can Kill

    Did you know that a single tablet from the medicine cabinet or ingestion of a teaspoon of a liquid  household product can potentially cause morbidity and even death in a child? 
     
    Dr. Jennifer Tucker, a Pediatric Emergency Physician, joins Dr. Rebecca Yang and Pediatric Resident James Davis to discuss the evaluation and management for specific common but dangerous household medications and substances in the household.  
    Review the basic assessment skills and evaluation for a child presenting with a potential toxic ingestion 
    Discuss the role of decontamination, diagnostic options, treatment and monitoring for toxic ingestions 
    Medications reviewed: Calcium Channel Blockers, Clonidine, Oral Hypoglycemics 
    Household products reviewed are those that contain toxic alcohols, benzocaine, Imidazoline, Camphor, and methylsalycylate 
    Anticipatory guidance to families regarding potential exposure/ingestion  
     Special thanks to Dr. George Hsu and Dr. Eric Ring for peer reviewing this episode. 
     
    Check out our website for detailed show-notes: https://www.augusta.edu/mcg/pediatrics/residency/podcast.php
    Questions, comments, or feedback? Please email us at mcgpediatricpodcast@augusta.edu 
     
    References:
    Deadly Pediatric Poisons: Nine Common Agents that Kill at Low Doses. MichaelJB, Sztajnkrycer MD. Emerg Med Clin North Am. 2004;22(4):1019–1050
    Toxic Ingestions: Initial Management. Courtney W. Mangus, Therese L. Canares. Pediatrics in Review Apr 2018, 39 (4) 219-221
    Tucker MD, Jennifer. "One Pill (Or Sip) Can Kill." MCG Pediatric Grand Rounds Presentation. Augusta, Georgia. July 15,2016.
     

    • 25 min
    IV Fluid Update

    IV Fluid Update

    Pediatric intensivist, Dr. Will Cagle joins the show to discuss the AAP Maintenance IV fluid guidelines and considerations when choosing IV fluids for pediatric inpatients.
    What do you need to know from the 2018 AAP maintenance IV fluid guideline? 
    How common is hyponatremia in hospitalized patients and why does it matter to your practice? 
    What is SIADH and how does it contribute to hyponatremia in acutely ill children? 
    How can we prevent hyponatremia in our hospitalized patients? 
    What are the differences between hypotonic and isotonic fluids? 
    What are balanced solutions and why might they be preferred as compared to saline in some clinical settings? 
    All of this and more from the Department of Pediatrics and the Medical College of Georgia. 
    Check out our website for detailed show-notes: https://www.augusta.edu/mcg/pediatrics/residency/podcast.php
    Special thanks to Dr. Asif Mansuri and Dr. Gene Fisher for providing peer review for this episode.
    Questions, comments, or feedback? Please email us at mcgpediatricpodcast@augusta.edu 
    Want Further Reading? Check out the clinical practice guideline from the AAP and our other references below.
    Feld LG, Neuspiel DR, Foster BA, et al. Clinical Practice Guideline: Maintenance Intravenous Fluids in Children. Pediatrics. 2018;142(6):e20183083. doi:10.1542/peds.2018-3083 
    Semler MW, Self WH, Wanderer JP, et al. Balanced Crystalloids versus Saline in Critically Ill Adults. N Engl J Med. 2018;378(9):829-839. doi:10.1056/NEJMoa1711584 
    Cuzzo B, Padala SA, Lappin SL. Vasopressin (Antidiuretic Hormone, ADH) [Updated 2020 Apr 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK526069/ 
    Chowdhury, Abeed H. BSc, MRCS*; Cox, Eleanor F. PhD†; Francis, Susan T. PhD†; Lobo, Dileep N. DM, FRCS, FACS* A Randomized, Controlled, Double-Blind Crossover Study on the Effects of 2-L Infusions of 0.9% Saline and Plasma-Lyte® 148 on Renal Blood Flow Velocity and Renal Cortical Tissue Perfusion in Healthy Volunteers, Annals of Surgery: July 2012 - Volume 256 - Issue 1 - p 18-24 doi: 10.1097/SLA.0b013e318256be72 
    Peti-Peterdi J, Harris RC. Macula densa sensing and signaling mechanisms of renin release. J Am Soc Nephrol. 2010;21(7):1093-1096. doi:10.1681/ASN.2009070759 
    Wilcox CS. Regulation of renal blood flow by plasma chloride. J Clin Invest. 1983;71(3):726-735. doi:10.1172/jci110820 

    • 22 min
    Kawasaki Disease

    Kawasaki Disease

    Dr. Pushpa Shivaram, an assistant professor of pediatrics and pediatric cardiologist at the Medical College of Georgia, joins Dr. Zac Hodges and Sonal Dugar (M4) to discuss this very important topic in pediatric medicine.
    What exactly is Kawasaki disease and why is this topic so important?
    How do you make the diagnosis and what other diagnoses should you consider?
    How can you diagnosis incomplete Kawasaki when the classic features are not all present?
    What is the first-line treatment?
    When should you get an echocardiogram?
    When should you get your referral center involved?
    All of this and more from the Department of Pediatrics and the Medical College of Georgia. 
    Check out our website for detailed show-notes: https://www.augusta.edu/mcg/pediatrics/residency/podcast.php
    Special thanks to Dr. Reda Bassali, Dr. Leizl Domingo and Dr. Julisa Patel for providing peer review for this episode.
    Questions, comments, or feedback? Please email us at mcgpediatricpodcast@augusta.edu 
    Further Reading? Check out the clinical practice guideline from the American Heart Association with citation below.
    McCrindle BW, Rowley AH, Newburger JW, et al. Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Scientific Statement for Health Professionals From the American Heart Association [published correction appears in Circulation. 2019 Jul 30;140(5):e181-e184]. Circulation. 2017;135(17):e927-e999. doi:10.1161/CIR.0000000000000484  
     
     

    • 26 min
    Bronchiolitis

    Bronchiolitis

    Dr. Reda Bassali, professor of pediatrics and pediatric hospitalist at the Medical College of Georgia, joins Dr. Zac Hodges and Gavriella Mendel (M3) to discuss this very important topic in pediatric medicine.
    What exactly is bronchiolitis and why is this topic so important?
    How do you make the diagnosis and what other diagnoses should you consider?
    What treatments work, and more importantly, which treatments do not?
    What patients can go home and who needs to be admitted?
    All of this and more from the Department of Pediatrics and the Medical College of Georgia. 
    Check out our website for detailed show-notes: https://www.augusta.edu/mcg/pediatrics/residency/podcast.php
    Special thanks to Dr. Kathryn McLeod for providing peer review for this episode.
    Citation:
    Hodges, Z. (Host). Bassali, R. (Host).  Mendel, G. (Host). McLeod, K. (Contributor). (2020, Nov 15). Bronchiolitis. (S1:18) [Audio Podcast Episode]. MCG Pediatric Podcast. Medical College of Georgia Augusta.
    Questions, comments, or feedback? Please email us at mcgpediatricpodcast@augusta.edu 
    Links: 
    NoseFrida-- https://www.nosefrida.com 
    References/further reading:
    Silver AH, Nazif JM. Bronchiolitis. Pediatr Rev. 2019;40(11):568-576. doi:10.1542/pir.2018-0260  
    Ralston SL, Lieberthal AS, Meissner HC, et al. Clinical practice guideline: the diagnosis, management, and prevention of bronchiolitis [published correction appears in Pediatrics. 2015 Oct;136(4):782]. Pediatrics. 2014;134(5):e1474-e1502. doi:10.1542/peds.2014-2742 
    Florin TA, Plint AC, Zorc JJ. Viral bronchiolitis. Lancet. 2017;389(10065):211-224. doi:10.1016/S0140-6736(16)30951-5  
    Cunningham S, Rodriguez A, Adams T, et al. Oxygen saturation targets in infants with bronchiolitis (BIDS): a double-blind, randomised, equivalence trial. Lancet. 2015;386(9998):1041-1048. doi:10.1016/S0140-6736(15)00163-4
    Franklin D, Babl FE, Schlapbach LJ, Oakley E, Craig S, Neutze J, Furyk J, Fraser JF, Jones M, Whitty JA, Dalziel SR, Schibler A. A Randomized Trial of High-Flow Oxygen Therapy in Infants with Bronchiolitis. N Engl J Med. 2018 Mar 22;378(12):1121-1131. doi: 10.1056/NEJMoa1714855. PMID: 29562151.
    Lin J, Zhang Y, Xiong L, Liu S, Gong C, Dai J. High-flow nasal cannula therapy for children with bronchiolitis: a systematic review and meta-analysis. Arch Dis Child. 2019 Jun;104(6):564-576. doi: 10.1136/archdischild-2018-315846. Epub 2019 Jan 17. PMID: 30655267.

    • 24 min
    Jude's Story & 22q11 Deletion Syndrome

    Jude's Story & 22q11 Deletion Syndrome

    Dr. Charles Scarborough joins the show to discuss the story of his son Jude, and his family's experience with his son's diagnosis with 22q11 deletion syndrome. 
    In addition to hearing about the Scarborough's personal experience, we talk about the genetic considerations and common clinical manifestations of 22q11.2 deletion syndrome.
    How do you approach the general diagnostic testing and screening evaluation of a child with 22q11.2 deletion syndrome?
    We also discuss the impact that genetic and chronic disease has on our pediatric patients and their families.
    Thanks to Dr. Paul Mann, Dr. Liezl Domingo and Dr. Jacqueline Chan for providing guidance and peer review of the technical material in this episode. 
    Citation:
    Hodges, Z. (Host). Scarborough, C. (Host).  Mann, P. (Contributor). Chan, J. (Contributor). Domingo, L. (Contributor).  (2020, Nov 1). Jude’s Story/22q11 Deletion Syndrome. (S1:17) [Audio Podcast Episode]. MCG Pediatric Podcast. Medical College of Georgia Augusta.  
    Links:
    MCG Pediatric Podcast: https://www.augusta.edu/mcg/pediatrics/residency/podcast.php 
    Georgia Medicaid Katie Beckett: https://medicaid.georgia.gov/programs/all-programs/tefrakatie-beckett 
    Clinica La fuente in Cusco, Peru http://www.lafuenteclinica.com/clinic-ingles/ 
    If you would like to donate to Clinica La fuente https://www.mtw.org/projects/details/pe-la-fuente-centro-de-salud-integral 
     
    Questions or comments? Contact us by email at mcgpediatricpodcast@augusta.edu 
     
    References:
    Cohen JL, Crowley TB, McGinn DE, et al. 22q and two: 22q11.2 deletion syndrome and coexisting conditions. Am J Med Genet A. 2018;176(10):2203-2214. doi:10.1002/ajmg.a.40494
    Campbell IM, Sheppard SE, Crowley TB, et al. What is new with 22q? An update from the 22q and You Center at the Children's Hospital of Philadelphia. Am J Med Genet A. 2018;176(10):2058-2069. doi:10.1002/ajmg.a.40637
    Vorstman JA, Jalali GR, Rappaport EF, Hacker AM, Scott C, Emanuel BS. MLPA: a rapid, reliable, and sensitive method for detection and analysis of abnormalities of 22q. Hum Mutat. 2006;27(8):814-821. doi:10.1002/humu.20330
    McDonald-McGinn DM, Sullivan KE. Chromosome 22q11.2 deletion syndrome (DiGeorge syndrome/velocardiofacial syndrome). Medicine (Baltimore). 2011;90(1):1-18. doi:10.1097/MD.0b013e3182060469
    Bassett AS, McDonald-McGinn DM, Devriendt K, et al. Practical guidelines for managing patients with 22q11.2 deletion syndrome.J Pediatr. 2011;159(2):332-9.e1. doi:10.1016/j.jpeds.2011.02.039

    • 35 min

Customer Reviews

5.0 out of 5
21 Ratings

21 Ratings

stjohnston ,

Even more informative than Scrubs!

Just found this podcast, huge fan! Can’t wait to hear more from Dr. Smith!!!

Top Podcasts In Science

Listeners Also Subscribed To