27: Alex Bisignano — Decoding Pandemic Genetics

Hi from Alice and the Flux team. We hope you are safe and well. 

In the latest episode I talk with Alex Bisignano, founder of Phosphorus is the second ever company to be approved by the FDA for at-home saliva testing to detect COVID-19. Alex has been on the frontlines of the pandemic in New York City. While most companies are using synthetic data, Alex and his team have collected live samples from patients in the lab.

Phosphorus has been able to rapidly develop virus and antibody test products, even though that wasn't the company's prior business. Alex shares how he thinks about supply chain reliability and how they are ramping up test manufacturing. We also get into genetics as a possible predictor for COVID-19 severity, which biological pathways may play a role, and what it would look like if we had large-scale biobanks.

If we are able to correctly identify who is at higher risk, what are the implications for employment and privacy policy? We get into the ethical questions around mandatory testing and disclosure and how countries like China have responded to the pandemic. Alex also reveals how he thinks Silicon Valley may shift in its attitude towards the hard sciences and biotech.

Full transcript on Medium. This episode was produced by Daniel Bouza.