54 episodes

Welcome to Infection and Immunity - Evidence Explained, a Doherty Institute podcast. Each fortnight we bring you the latest news and information on all things infectious diseases and immunology from the Doherty Institute and our collaborators.

Join us as we talk with world-leading experts to discuss the latest scientific and public health evidence around emerging and endemic diseases, from COVID-19 and Buruli ulcer, to HIV and the flu.

Infection and Immunity Doherty Institute

    • Science
    • 5.0 • 30 Ratings

Welcome to Infection and Immunity - Evidence Explained, a Doherty Institute podcast. Each fortnight we bring you the latest news and information on all things infectious diseases and immunology from the Doherty Institute and our collaborators.

Join us as we talk with world-leading experts to discuss the latest scientific and public health evidence around emerging and endemic diseases, from COVID-19 and Buruli ulcer, to HIV and the flu.

    Diagnosis and treatment of Long COVID

    Diagnosis and treatment of Long COVID

    Post infection disease is a term that has become more familiar to many more of us following the COVID-19 pandemic. How do we diagnose and treat post infection disease, like Long COVID? And how to we add this aspect to our future pandemic preparedness?

    Learn more about common symptoms, at-risk groups and more from Long COVID expert Professor Lena Sanci, Head of the Department of General Practice and Primary Care at the University of Melbourne.

    Get in touch

    Have a question or topic you'd like us to explore in a future episode? Contact us via email doherty-media@unimelb.edu.au
    See omnystudio.com/listener for privacy information.

    • 32 min
    When should I get my COVID-19 booster?

    When should I get my COVID-19 booster?

    With COVID-19 being described as an endemic infection, we are now very much living with the virus. As we approach the Winter months in Australia, where are we at with case numbers? When is the correct time to get a your booster vaccination for COVID-19? And how effective are antiviral treatments?

    To give us an update on COVID-19, we're joined by Professor Ben Cowie, an infectious diseases physician and epidemiologist at the Royal Melbourne Hospital and Chief Health Officer in Victoria’s Department of Health.

    Show notes

    COVID-19 vaccine advice and recommendations for 2024 - Australian Government Department of Health and Aged Care website

    COVID-19 booster eligibility checker - Australian Government Department of Health and Aged Care website

    Get in touch

    Have a question or topic you'd like us to explore in a future episode? Contact us via email doherty-media@unimelb.edu.au
    See omnystudio.com/listener for privacy information.

    • 18 min
    Why clinical trials are vital for developing new vaccines and therapeutics

    Why clinical trials are vital for developing new vaccines and therapeutics

    Monday, 20 May marked International Clinical Trials Day, which recognises the anniversary of the first controlled clinical trial conducted back in 1747.

    So why are clinical trials important when it comes to advancing therapeutics and vaccines? Are clinical trials safe? What's involved if you participate in a trial? We learn more from infectious diseases physician and clinician scientist, Professor Michelle Giles, head of the Vaccine Research Group at the Doherty Institute.

    Show notes:

    Now recruiting volunteers: Are you interested in being part of an RSV vaccine study?

    Get in touch

    Want to join the Vaccine Research Group database to find out about clinical trial volunteer opportunities? 

    Email: virgo-studies@unimelb.edu.au

    Phone: +61 3 8344 9325 or +61 4 1832 2346

    Have a question or topic you'd like us to explore in a future episode? Contact us via email doherty-media@unimelb.edu.au
    See omnystudio.com/listener for privacy information.

    • 22 min
    Influenza B breakthrough: promising targets for vaccine development

    Influenza B breakthrough: promising targets for vaccine development

    Influenza B viruses are often overlooked but can cause significant illness and mortality, especially in children. Little is known about how the immune system interacts with these viruses, however a recent breakthrough by researchers at the Doherty Institute may revolutionise how we are protected against influenza B and for longer periods.

    Tejas Menon, co-author of the recent discovery and PhD Candidate at the Doherty Institute, explains how the immune system consistently recognises fragments of influenza B viruses, which opens up potential new targets for vaccine development.

    Show notes:

    News story: New frontiers in influenza B research: Breakthrough unveils promising targets for vaccine development

    Peer review: Menon T, Illing P, Chaurasia P, et al. CD8+ T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age. Nature Communications (2024). DOI: https://doi.org/10.1038/s41467-024-47576-y  

    Check out our previous episode: Here’s what you need to know about flu season 2024

    Get in touch

    Have a question or topic you'd like us to explore in a future episode? Contact us via email doherty-media@unimelb.edu.au
    See omnystudio.com/listener for privacy information.

    • 10 min
    How the immune system works with Peter Doherty

    How the immune system works with Peter Doherty

    Does your immune system remember viruses you've previously been infected with? Do your genetics play a role in your immune system? Can you boost immunity with certain foods or vitamins?

    Ahead of the International Day of Immunology (April 29) we chat with Nobel Laureate Professor Peter Doherty to answer these questions and more, unravelling the complexities and exploring the wonders of our body's line of defence against disease; our immune system.

    Show notes:

    An Insider's Plague Year written by Peter Doherty 

    The Nobel Prize in Physiology or Medicine 1996 was awarded jointly to Peter C. Doherty and Rolf M. Zinkernagel "for their discoveries concerning the specificity of the cell mediated immune defence"

    Get in touch

    Have a question or topic you'd like us to explore in a future episode? Contact us via email doherty-media@unimelb.edu.au
    See omnystudio.com/listener for privacy information.

    • 36 min
    Here’s what you need to know about flu season 2024

    Here’s what you need to know about flu season 2024

    We’re just a couple of weeks away from May, which marks the official start of the influenza season in Australia. So what can we expect from the upcoming flu season and when is the best time to get your annual flu vaccine? 

    Learn more about flu vaccination, virus variants and current influenza surveillance from Virologist and Director of the World Health Organization Collaborating Centre for Reference and Research on Influenza, Professor Kanta Subbarao.

    Show notes:

    Learn more about Influenza vaccination and the National Immunisation Program via the Australian Government Department of Health and Aged Care website.

    Interested in the work of the WHO Collaborating Centre for Reference and Research on Influenza at the Doherty Institute? Visit the Centre website.

    Check out our episode on avian influenza: Avian influenza (H5N1): why are experts concerned about the virus reaching Antarctica?

    Find out about recent announcement of funding from the Novo Nordisk Foundation to develop a novel antiviral drug to counter influenza.

    Get in touch

    Have a question or topic you'd like us to explore in a future episode? Contact us via email doherty-media@unimelb.edu.au
    See omnystudio.com/listener for privacy information.

    • 23 min

Customer Reviews

5.0 out of 5
30 Ratings

30 Ratings

Cxlnt ,

My favourite podcast for all things science

Delighted that the Doherty Institute podcast is back. What is I love is how the compact format of the episodes and hearing about the science straight from the people who conduct the research, rather than having it relayed and diluted. Keep up he good work!

Frances Albers ,

Evidence Explained Eloquently

I devoured this podcast during my own COVID-positive isolation period. The evidence has indeed been explained eloquently. The perspectives of some incredible scientific experts on the COVID response frontline has also been very valuable to listen to as an epidemiology student.

Gilx76 ,

Fantastic podcast

A great podcast with up to date, accurate info and gives a helpful perspective on the pandemic that we don’t hear in the mainstream media. I really like the expert guests they have each week.

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