Infection Control Matters Brett Mitchell

In this episode, Phil, Brett and Martin dicuss more sessions from ESCMID Global (Barcelona, 2024). We talk about sessions on cleaning the occupied bed space, SSI prevention and the difficulty of designing and executing good studies in IPC. We were particularly interested in papers from Italy on the use of probiotics in IPC and some papers from Prof Cassini's group are highlighted below.
Calabro GE, Caselli E, Rognoni C, Laurenti P, Moscato U, ML DIP, et al. [Health Technology Assessment of the introduction of the Probiotic Cleaning Hygiene System (PCHS) in the Italian healthcare setting: update]. J Prev Med Hyg. 2023;64:E1-E35. https://www.ncbi.nlm.nih.gov/pubmed/37881619
D'Accolti M, Soffritti I, Bini F, Mazziga E, Cason C, Comar M, et al. Shaping the subway microbiome through probiotic-based sanitation during the COVID-19 emergency: a pre-post case-control study. Microbiome. 2023;11:64. https://www.ncbi.nlm.nih.gov/pubmed/36991513
D'Accolti M, Soffritti I, Bini F, Mazziga E, Mazzacane S, Caselli E. Pathogen Control in the Built Environment: A Probiotic-Based System as a Remedy for the Spread of Antibiotic Resistance. Microorganisms. 2022;10. https://www.ncbi.nlm.nih.gov/pubmed/35208679
Caselli E, Purificato I. Could we fight healthcare-associated infections and antimicrobial resistance with probiotic-based sanitation? Commentary. Ann Ist Super Sanita. 2020;56:263-6. https://www.ncbi.nlm.nih.gov/pubmed/32959791|
Caselli E, D'Accolti M, Vandini A, Lanzoni L, Camerada MT, Coccagna M, et al. Impact of a Probiotic-Based Cleaning Intervention on the Microbiota Ecosystem of the Hospital Surfaces: Focus on the Resistome Remodulation. PLoS One. 2016;11:e0148857. https://www.ncbi.nlm.nih.gov/pubmed/26886448

In this episode, Brett, Martin and Phil mull over the newly published WHO discussion document on respiratory particles and Martin catches up with Prof Cath Noakes from the School of Engineering in Leeds, UK to get her take on it.
 
You can download the document we are discussing here
https://www.who.int/publications/m/item/global-technical-consultation-report-on-proposed-terminology-for-pathogens-that-transmit-through-the-air

In this podcast, Brett and Martin reflect on the "Infection Control Papers of the Year" presented at ECCMID (AKA ESCMID Global) 2024.
Here are a selection of some of the papers mentioned:

Decolonization in Nursing Homes to Prevent Infection and Hospitalization https://pubmed.ncbi.nlm.nih.gov/37815935/


Reducing Hospitalizations and Multidrug-Resistant Organisms vi a Regional Decolonization in Hospitals and Nursing Homes https://pubmed.ncbi.nlm.nih.gov/38557703/


Prevention of non-ventilator-associated hospital-acquired pneumonia in Switzerland: a type 2 hybrid effectiveness-implementation trial https://pubmed.ncbi.nlm.nih.gov/36893785/


Skin Antisepsis before Surgical Fixation of Extremity Fractures https://www.nejm.org/doi/full/10.1056/NEJMoa2307679


Trial of Vancomycin and Cefazolin as Surgical Prophylaxis in Arthroplasty https://www.nejm.org/doi/full/10.1056/NEJMoa2301401

Investigation of individual nurses' relative hand hygiene performance using an anonymous automated electronic hand hygiene monitoring system and a nursing assignment schedule https://www.ajicjournal.org/article/S0196-6553(22)00468-0/abstract

Environmental cleaning to prevent hospital-acquired infections on non-intensive care units: a pragmatic, single-centre, cluster randomized controlled, crossover trial comparing soap-based, disinfection and probiotic cleaning https://pubmed.ncbi.nlm.nih.gov/37089619/

In our first episode from ECCMID Global 2024, Martin and Brett reflect on the session on design of the healthcare environment sessions from Profs Hilary Humphries and Cath Noakes and a flash poster session featuring VRE Reservoirs in the environment and a tremendous piece of  Burkolderia sleuthing from the UKHSA

In this podcast, we chat with Dr Brian Forde about HAIviz. HAIviz an interactive dashboard for visualising and integrating healthcare-associated genomic epidemiological data.

In this episode, Martin Kiernan talks to Mitch Clarke, Clinical Lead and Deputy Director of Infection Prevention and Control at Nottingham University Hospitals in the UK. We discuss an outbreak with a unique NDM CPE infection and look at where the investigations went, including a new reservoir that is a potential source - the floor scrubber.
Papers underpinning this work are here:
1. Benbow A, Clarke M, Yates C, Montgomery R, Staniforth K, Boswell T, et al. Hospital-wide healthcare-associated carbapenemase-producing Enterobacterales outbreak: risks of electric floor scrubbers in catering facilities and kitchens. J Hosp Infect. 2024;146:59-65. https://www.ncbi.nlm.nih.gov/pubmed/38341149 2. Prescott K, Billam H, Yates C, Clarke M, Montgomery R, Staniforth K, et al. Outbreak of New Delhi Metallo-Beta-lactamase Carbapenemase Producing Enterobacterales on a bone marrow transplant unit: Role of the environment. Infect Prev Pract. 2021;3:100125. https://www.ncbi.nlm.nih.gov/pubmed/34368742