CannMed Coffee Talk

Medicinal Genomics
CannMed Coffee Talk

Brought to you by Medicinal Genomics

  1. Making High Science TV with Ed Leclere and David McKillop

    HÁ 11 H

    Making High Science TV with Ed Leclere and David McKillop

    Ed Leclere and David McKillop have teamed up to create High Science, a new TV series premiering on YouTube TODAY November 27th featuring Medicinal Genomics and CannMed. David is an Emmy-award-winning producer with an impressive background in creating hit shows like Duck Dynasty and Pawn Stars. He brings his storytelling expertise to the cannabis space, teaming up with Ed Leclere to launch a show that’s as entertaining as it is informative. High Science promises to take viewers on a journey through the world of cannabis, focusing on its therapeutic potential, the people who grow it, and the science that drives it forward. During our conversation, we discuss: Ed’s personal health journey and how it inspired the show's creation The show’s goal to make the medical science of cannabis more accessible to the public and reduce cannabis stigma. The challenges that cannabis entrepreneurs face in the form of strict regulations, financial challenges, and a thriving black market. How the series uses personal storytelling to balance education and entertainment. Why YouTube was chosen for its global reach and creative freedom compared to traditional networks. A glimpse into future seasons which may explore other plant medicines, such as mushrooms. Thanks to This Episode's Sponsor: High Science TV High Science TV shares the lively exploits of colorful characters around the world, trailblazing all things cannabis in pursuit of the modern-day gold rush. Father/son show hosts Rich Batenburg Jr. and Richard “Rick” Batenburg III explore legendary seed gurus, relentless cultivators, expansive growers, pioneering product makers and imaginative dispensary owners as they break the barriers of this new frontier. The storytelling unmasks the mystical powers of the ancient cannabis plant and its innumerable uses through dynamic entertainment. High Science premieres on YouTube November 27th at YouTube.com/@HighScienceTV. Additional Resources Watch High Science HighScience.com Register for CannMed 25 Meet the CannMed 25 Advisory Board Review the Podcast CannMed Archive

    45min
  2. Analyzing Cannabis Gene Expression with Kevelin Barbosa-Xavier

    13 DE NOV.

    Analyzing Cannabis Gene Expression with Kevelin Barbosa-Xavier

    Kevelin Barbosa-Xavier is a PhD student in Plant Biotechnology at Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF) where she conducts research under the supervision of Thiago Motta Venancio. She is a computational biologist, investigating the genes and gene networks involved in plant secondary metabolic pathways and fiber production, specifically in the Cannabis sativa species. Kevelin and her team recently published a study titled Cannabis Expression Atlas: a comprehensive resource for integrative analysis of Cannabis sativa L. gene expression, along with a free online tool to help researchers analyze genomic sequence data. We discussed: The team’s main objectives in creating the Cannabis Expression Atlas How our understanding of cannabis genomics compares to other commercial crops How gene expression data can advance plant breeding and genetic engineering Potential applications of the Cannabis Expression Atlas in commercial cannabis cultivation and more Thanks to This Episode's Sponsor: Medicinal Genomics Medicinal Genomics (MGC) uses its unmatched knowledge of the cannabis genome and the microbes affecting cannabis plants to create diverse testing solutions that improve crop yield, accelerate breeding programs, and ensure product safety. Growers and breeders use MGC’s cannabis genome sequencing services to identify novel traits, stabilize genetics, and protect intellectual property. Additionally, Kannapedia.net provides bioinformatics and blockchain certification for cultivar authenticity. Learn more at medicinalgenomics.com Additional Resources Cannabis Expression Atlas: a comprehensive resource for integrative analysis of Cannabis sativa L. gene expression Cannabis Expression Atlas Register for CannMed 25 Meet the CannMed 25 Advisory Board Submit Your Abstract for CannMed 25 Review the Podcast CannMed Archive

    25min
  3. Investigating Cannabinoids for PTSD Relief with Laura Barrett

    30 DE OUT.

    Investigating Cannabinoids for PTSD Relief with Laura Barrett

    Laura Barrett, MBA, BSN, RN, known as “Nurse Laura,” is the Founder and Executive Director of the National Clinical Director Consortium and the Owner and Operator of Ask Nurse Laura. She serves on the boards of several non-profits, including the Connor Sheffield Foundation. Nurse Laura is dedicated to educating individuals and groups about cannabis and psychedelic medicine options, whether in small settings or large conference auditoriums.  Additionally, she is part of the teaching faculty at the University of Maryland's School of Pharmacy and New York University's Business School where she teaches multiple courses - including the collaborative development of a psychedelic elective course for the Masters of Cannabis Science and Therapeutics program. She also conducts training sessions with healthcare provider groups and nursing organizations, delving into state-specific regulations, products, and access for providers. Collaborating closely with pharmacists, providers, and fellow nurses in the cannabis industry, Nurse Laura promotes valuable educational resources for healthcare professionals, patients, and dispensary staff. Her mission is to enhance consistency and reliability in the educational opportunities available, specifically in healthcare. Nurse Laura has hands-on experience in various aspects of the cannabis industry, including cultivation, processing, dispensary operations, sales, marketing, and compliance. She emphasizes the importance of understanding laws and regulations, reviewing scientific research, and gathering patient data to create accessible presentations that support public health. Her balanced approach to cannabis and hemp integrates them into a holistic view of wellness.  Nurse Laura stays informed about current research on the medicinal use of cannabis and psychedelics to help patients and her peers assess the benefits and risks unique to everyone. She crafts tailored care plans incorporating well-established practices that she and her industry peers aim to standardize. Beloved by her patients for their improved health and respected by fellow practitioners for her perseverance and dedication, Nurse Laura is committed to advancing the evolving field of plant medicine therapeutics. Laura is currently working with the Connor Sheffield Foundation on an observational research study about the use of cannabis to treat symptoms of Post Traumatic Stress Disorder (PTSD).  During our conversation we discuss:  How cannabinoids affect trauma responses and support cognitive therapy  Details about the research study, including who should participate and how data will be collected  How patients use different routes of administration, cannabinoid ratios, and dosages to manage certain symptoms  The challenges of doing cannabinoid research and the need for standartization across the US  and more  Thanks to This Episode's Sponsor: McKinney RSA McKinney is made up of regulatory science veterans who apply lessons learned in the nicotine space to help cannabis manufacturers better understand the toxicological and societal implications of their product.  They do that by Identifying base compounds, extracts, flavors and terpenes, understanding how they interact, and ensuring effectiveness for the intended use. They also provide dosing recommendations and establish guidelines for product consistency.  Learn more at mckinneyrsa.com  Additional Resources Connor Sheffield Foundation PTSD Research Study Link AskNurseLuara.com

    46min
  4. Cannabinoids for Athletics, Concussions, and Pain with Elizabeth Thompson

    16 DE OUT.

    Cannabinoids for Athletics, Concussions, and Pain with Elizabeth Thompson

    With a BSc. in molecular biology and an MSc. in physiology, Liz has studied the human body through many lenses. The focus of her PhD program (Pharmacy) is to explore disorders that have directly impacted her life in the world of professional contact sports, and how cannabinoid products could potentially play a role in these.  As a member of the clinical trial team that was recently awarded funding from the NFL to study cannabinoids in concussion and pain, she is excited to bring new data to the literature exploring cannabinoids and athletics. Liz and her team recently published an extensive literature review titled Cannabinoid Therapy in Athletics: A Review of Current Cannabis Research to Evaluate Potential Real‑World Cannabinoid Applications In Sport, which establishes a foundation for their future research.   During our conversation, we discussed:  How Liz became interested in the therapeutic potential of cannabinoids Published literature that supports using cannabinoids for neuroinflammation and neurodegenerative disorders Her team’s collaboration with the NFL and ongoing clinical trials focused on neuroinflammation and recovery in athletes, particularly after concussions Current use of cannabis in athletics and how sports organizations are changing their policies  Future directions of research  and more  Thanks to This Episode's Sponsor: The DENT Institute With more than 300,000 patient visits per year, the DENT Neurologic Institute ranks among the largest neuroscience centers in North America. Its 24 subspecialty clinics often treat the most challenging neurologic conditions including but not limited to Migraine, Chronic pain, ALS, MS, Parkinson’s, Dementia, and Neuro-Oncology. With their mission of advancing neuroscience, the Dent Institute established a cannabis clinic in 2016 to aid in the treatment of these chronic conditions seen throughout the institute. Learn more at dentinstitute.com Additional Resources Cannabinoid Therapy in Athletics: A Review of Current Cannabis Research to Evaluate Potential Real‑World Cannabinoid Applications In Sport trainwithmaryjane.com Train with Mary Jane on Instagram Submit Your Abstract for CannMed 25 Review the Podcast CannMed Archive

    55min
  5. Surveying Cannabinoid Hyperemesis Syndrome with Megan Mbengue and Codi Peterson

    2 DE OUT.

    Surveying Cannabinoid Hyperemesis Syndrome with Megan Mbengue and Codi Peterson

    Megan Mbengue is the revolutionary force behind Trusted Canna Nurse. With over 10 years of nursing experience in diverse fields like oncology, labor delivery, and hospice care, she brings a unique perspective to her practice. She also holds national certifications in three nursing specialties and a Master of Science degree in Medical Cannabis Therapeutics. Codi Peterson is the Chief Science Officer at The Cannigma and a practicing pharmacist with a passion for cannabis-based medicine. Given his diverse pediatric pharmacy experience and knack for educating, he aims to educate as many as possible about the medicinal potential of cannabis Codi and Megan have launched a new IRB-approved survey through the University of California that aims to better understand the signs, symptoms, and challenges of CHS. They want to understand the key indicators of this condition, hear about any remedies that work, and learn more about navigating healthcare as a CHS patient.  If you or someone you know has suffered from CHS (and are over 18), please take a moment to fill out their survey. Not only will you be helping this vital research, but participants will be entered into a drawing to win one of three $100 gift cards. I’ve put a link in the show description so it’s easy to find.  During our conversation, we discuss:  Overview of CHS symptoms   Early Symptoms and the Prodrome Phase  Clinical experiences treating CHS patients  The Potential Causes   Challenges in diagnosing CHS  Treatment and Abstinence from Cannabis  Thanks to This Episode's Sponsor: Trusted Canna Nurse Trusted Canna Nurse was founded by Megan Mbengue and Ariane Williams, two nurses who are dedicated to bridging the gap between traditional medicine and the world of cannabis and psychedelics. They specialize in creating evidence-based treatment plans for all ages that address chronic illnesses, treatment-resistant conditions, mental health, autism, and more.  Learn more at trustedcannanurse.com  Additional Resources Take the CHS Survey! Cannabinoid Hyperemesis Syndrome What You Need to Know [Video] what-is-chs.com Connect with Megan (Instagram, LinkedIn) Connect with Codi (Instagram, LinkedIn) Submit Your Abstract for CannMed 25 Review the Podcast CannMed Archive

    51min
  6. Breeding Techniques to Create Unique Genetics with Justin Esquivel

    18 DE SET.

    Breeding Techniques to Create Unique Genetics with Justin Esquivel

    Justin Esquivel is CEO & Geneticist, Green Luster Phenos™ and has been an influencer and leader in the cannabis industry for 15 years. Esquivel was the head grower and geneticist of an indoor commercial-scale cultivation operation back in 2012.  Justin has consulted with over 100 cannabis facilities, 72 of which operate commercial canopies.  Esquivel provides home growers with pest and bacteria-resistant genetics in seed and breeders’ cut form on a global scale!  He brings standard operating procedures to a gold standard.  His one-of-a-kind approach to plasticity breeding has sparked tons of interest across the globe.  Esquivel also specializes in Cannabis Tissue Culture & Selective Homozygous Breeding, enabling his company to bring exotic tailored offspring to growers globally!During our conversation, we discuss:  Justin’s background in traditional ag and how that applies to cannabis  How he uses tissue culture to store genetics and eliminate pathogens  The process for creating stable cannabis varieties How purposely introducing pests into the breeding room helps select for resistance traits  The application of analytical tools, such as PCR, HPLC, and marker-assisted breeding  Thanks to this episode’s Sponsor: Rare Earth Genomics.  Rare Earth Genomics is a dynamic partnership formed with Texas A&M AgriLife, one of the world’s leading research institutions, to accelerate hemp research and create tools for farmers. Their mission is to increase the likelihood of a successful harvest for farmers through genetic analysis and rigorous environmental testing of vigorous cultivars.  Learn more at rareearthgenomics.com  Additional Resources:  greenlusterphenos.com Review the Podcast CannMed Archive

    39min
  7. Investigating Terpenes for Chronic Pain Management with John Stretcher, PhD

    4 DE SET.

    Investigating Terpenes for Chronic Pain Management with John Stretcher, PhD

    Dr. John Streicher is a Professor in the Department of Pharmacology in the College of Medicine at the University of Arizona. He has built a long-term research program focused on finding improved treatments for pain. This has encompassed multiple approaches over the years, including testing cannabinoid and non-cannabinoid constituents of Cannabis sativa, identifying new ways to target opioid receptor signaling, and identifying new receptor targets in the body for pain relief. His lab works on both the basic science knowledge of how these systems work and also works to create new drugs for human therapy. During our conversation, we discussed: The basics of terpenes. What they are and their role in cannabis The cannabimimetic effects of terpenes and their synergistic effects with cannabinoids What levels of terpenes are needed to get a therapeutic effect A recent study showing terpenes can relieve chronic neuropathic pain Combining terpenes with other drugs, such as opioids, to get better pain relief at lower doses Which terpenes provide the best pain relief Thanks to This Episode's Sponsor: Healer Healer is a trusted, physician-developed medicinal cannabis brand founded to address the challenges of helping people and health providers get the best results with safe, reliably dosable products and education on how to best use them. Healer Hemp products are available nationwide and include a step-by-step usage guide and response tracker. Healer’s distinctive product formulations and education are based on the latest research and work of leading cannabis clinician, Dr. Dustin Sulak, D.O. Visit Healer.com or HealerCbd.com Additional Resources: Terpenes are Cannabimimetic and Enhance Cannabinoid Activity Terpenes Relieve Chronic Pain A Review Article of Terpenes in Pain A Screen of Minor Cannabinoids in Pain The University of Arizona Comprehensive Center for Pain and Addiction Review the Podcast CannMed Archive

    33min
  8. Preserving Cannabis Beverage Potency with Harold Han, PhD

    21 DE AGO.

    Preserving Cannabis Beverage Potency with Harold Han, PhD

    Dr. Harold Han is Chief Science Officer and co-founder of Vertosa, and the pioneer in water compatible cannabinoid ingredients for infused products. Harold designed the industrial leading cannabis emulsions that are widely applied in the cannabis beverage brands. Harold holds 16 patents in emulsion applications, and prior to founding Vertosa, he led a team that developed the emulsification oil for Bio Rad’s Digital Droplet PCR system. Harold also publishes a regular series explaining the science of cannabis for product makers under the monicker "The Happy Chemist" — a nickname you'll understand after you watch the interview. One of his recent articles describes the different factors that contribute to cannabis beverage potency loss, which is a challenge for beverage brands. In fact, in regulated markets it’s common to see a 10-15% variation in potency compared to the label claim. In unregulated hemp-derived beverages, it can be even higher. During the conversation we discuss The difference between cannabis beverages and alcoholic beverages What happens when cannabinoids oxidize How to put THC into water-based products using physical and chemical processes How every aspect of the supply chain can lead to potency loss in cannabis beverages Which beverage ingredients hasten potency loss How packaging conditions can affect scalping and oxidation rates Thanks to This Episode's Sponsor: Vertosa Vertosa creates industry-leading active ingredients for infused product makers. Their patent-pending nano- and micro-emulsions are carefully designed for the specific needs of each customer, and their pre-suspended aqueous solutions empower them to create incredibly homogenous and stable products while maximizing bioavailability, clarity, and taste. Learn more at Vertosa.com Additional Resources Happy Chemist Article Series The Cannabis Beverage Manufacturing Handbook Review the Podcast CannMed Archive

    46min

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