19 Min.

ADAMTS13 recovery in caplacizumab-treated TTP; inhibition of venetoclax-resistant BCL2 variants with sonrotoclax; genomic insights from Castleman disease in twins Blood Podcast

    • Wissenschaft

In this week's epside we'll learn about ADAMTS recovery after caplacizumab therapy in patients with immune thrombotic thrombocytopenic purpura. Then, we'll hear about preclinical characterization of sonrotoclax, a potential second-generation BCL2 inhibitor. Finally we'll hear about new insights into the etiology of Castleman disease where researchers describe the unusual occurrence of idiopathic multicentric Castleman disease in identical twins. 
Featured Articles: 
ADAMTS13 recovery in acute thrombotic thrombocytopenic purpura after caplacizumab therapySonrotoclax overcomes BCL2 G101V mutation–induced venetoclax resistance in preclinical models ofhematologic malignancySingle-cell landscape of idiopathic multicentric Castleman disease in identical twins

In this week's epside we'll learn about ADAMTS recovery after caplacizumab therapy in patients with immune thrombotic thrombocytopenic purpura. Then, we'll hear about preclinical characterization of sonrotoclax, a potential second-generation BCL2 inhibitor. Finally we'll hear about new insights into the etiology of Castleman disease where researchers describe the unusual occurrence of idiopathic multicentric Castleman disease in identical twins. 
Featured Articles: 
ADAMTS13 recovery in acute thrombotic thrombocytopenic purpura after caplacizumab therapySonrotoclax overcomes BCL2 G101V mutation–induced venetoclax resistance in preclinical models ofhematologic malignancySingle-cell landscape of idiopathic multicentric Castleman disease in identical twins

19 Min.

Top‑Podcasts in Wissenschaft

Aha! Zehn Minuten Alltags-Wissen
WELT
Sternengeschichten
Florian Freistetter
Das Wissen | SWR
SWR
Quarks Daily
Quarks
radioWissen
Bayerischer Rundfunk
KI verstehen
Deutschlandfunk