Editors in Conversation

American Society for Microbiology
Editors in Conversation

Editors in Conversation is the official podcast of the American Society for Microbiology Journals. Editors in Conversation features discussions between ASM Journals Editors, researchers and clinicians working on the most cutting edge issues in the microbial sciences. Topics include laboratory diagnosis and clinical treatment of infectious diseases, antimicrobial resistance, epidemiology of infections, multidrug-resistant organisms, pharmacology of antimicrobial agents, susceptibility testing, and more. The podcast is directed to microbiologists, infectious diseases clinicians, pharmacists and basic, clinical and translational researchers interested in the microbial sciences. A particular emphasis is on basic, epidemiological and pharmacological aspects of infectious diseases, including antimicrobial resistance and therapeutics.

  1. 13. DEC.

    The Global Antibiotic Research & Development Partnership (GARDP)

    Lack of access to antibiotics including those with enhanced activity against multidrug-resistant organisms is a major barrier to combat antimicrobial resistance, particularly in the developing world. Furthermore, discovering and making available new antimicrobial agents against the most pressing antibiotic-resitant organisms is a challenge due to multiple barriers. The Global Antibiotic Research & Development Partnership (GARDP) accelerates the development and access of treatments for drug-resistant bacterial infections. Together with public, private and non-profit partners, GARDP works to preserve the power of antibiotics for generations to come. We discuss the important role that GARDP is playing in the worldwide fight against antimicrobial resistance. Topics discussed: GARDP function and role in the AMR field The strategies that GARDP is implementing to make new antibiotics available to all The future of antimicrobial research and development and the role of GARDP in this process. Guests: Jennifer Cohn MD MPH, Director, Global Access Global Antibiotic R&D Partnership (GARDP) Susana Ribeiro, MPH, Regional Head Latin America Global Antibiotic R&D Partnership (GARDP) This episode is brought to you by the Antimicrobial Agents and Chemotherapy Journal.  Visit asm.org/aac to browse issues and/or submit a manuscript. If you plan to publish in AAC, ASM Members get up to 50% off publishing fees. Visit asm.org/joinasm to sign up.

    41 min.
  2. 11. NOV.

    At-Home Collection and Testing for STIs

    So you want validated, at-home, self-collected swabs for STI testing… Here's what you need to know!  Sexually transmitted infection rates continue to climb across the US and while testing for these diseases is widely available, for the most part it requires the patient to go to a local clinic to collect and submit their sample for testing. But, is that really necessary, especially from a test accuracy perspective? Today’s guests answer that exact question. And I’m sure that many, if not all of us would agree that the ability for patients to collect samples outside of a clinical setting has numerous benefits, including what the authors refer to as pseudo-anonymity, increased comfort and ultimately increased access to testing, which would be of particular value for patients that may avoid clinical settings due to various different socioeconomic barriers.  Watch this episode: https://youtu.be/40XCHpAFvqw Guests: Dr. Breland Hockman, who is a board certified clinical chemist and the Director of Clinical Affairs at LetsGetChecked.com Dr. Dina Greene, Clinical Professor at University of Washington, Department of Laboratory Medicine and Pathology and former Associate Lab Director at LetsGetChecked.com Links: Overcoming analytical and preanalytical challenges associated with extragenital home collected STI specimens Join ASM for up to 50% off the publication fees when you publish in JCM or any of the ASM journals. This episode of Editors in Conversation is brought to you by the Journal of Clinical Microbiology and hosted by JCM Editor in Chief, Alex McAdam and Dr. Elli Theel. JCM is available at https://jcm.asm.org and on https://twitter.com/JClinMicro. Visit journals.asm.org/journal/jcm to read articles and/or submit a manuscript. Follow JCM on Twitter/𝕏 via @JClinMicro

    35 min.
  3. 26. OKT.

    High Level Meeting on AMR at the United Nations: A Debrief

    The second High-Level Meeting on Antimicrobial Resistance (AMR) took place in New York on 26 September 2024 as the principal official, health-focused event during the UN General Assembly high-level week. The intergovernmental negotiations for the declaration were co-facilitated by Malta and Barbados. A political declaration for the meeting was produced highlighting the fact that AMR will cause even more global suffering, particularly in low- and middle-income countries. In this episode we will debrief and analyze the possible impact of these meetings and consequences for the future of AMR research and antimicrobial development.  Topics discussed: The political implications of the UN declaration on AMR. Comment of the scientific and public health impact of the declaration Elaborate on future antimicrobial research and development Guests: John Rex, MD. Chief Medical Officer, F2G Ltd; Operating Partner, Advent Life Sciences Prabha Fernandes, PhD. Board Member of GARDP (Global Antibiotic Research and Development Partnership). Links: HLM on AMR at UNGA: The end of the beginning 29 April 2024: “R&D Implications: Global Burden of Disease is 28% Infectious!” 27 Sep 2024: “Without action, AMR costs go from $66b to $159b/yr by 2050” This episode is brought to you by the Antimicrobial Agents and Chemotherapy journal.  Visit asm.org/aac to browse issues and/or submit a manuscript. If you plan to publish in AAC, ASM Members get up to 50% off publishing fees. Visit asm.org/joinasm to sign up.

    49 min.
  4. 13. SEP.

    Heteroresistance: Mechanisms, Diagnosis and Clinical Implications

    Heteroresistance is a phenomenon that has been well characterized for many years. However, we are only now starting to understand its mechanistic basis. Indeed, the manner how bacteria respond to antibiotics is complex and phenomena such as persistance, tolerance may be overlapping with heteroresistance. Furthermore, heteroresistance seems to be common in real clinical scenarios and understanding its basis is likely to open new avenues on how we deploy antibacterials in clinical practice., Today, we have experts in the field to discuss this important topic. Watch this episode at https://youtu.be/qcIcyn1bIHU. Topics discussed: The differences between heteroresistance, persistence and tolerance The mechanistic basis both in Gram-positive and Gram-negative bacteria The clinical implication and diagnosis of heteroresistance Guests: David Weiss, Ph.D. Professor of Medicine and Director Center for Antimicrobial Resistance, Emory University School Of Medicine, Atlanta. GA. William Miller, MD. Assistant Professor of Medicine, Houston Methodist, Houston, TX and Weill Cornell Medical College, New York, NY. Links: Cefiderocol heteroresistance associated with mutations in TonB-dependent receptor genes in Pseudomonas aeruginosa of clinical origin This episode is brought to you by the Antimicrobial Agents and Chemotherapy journal.  Visit asm.org/aac to browse issues and/or submit a manuscript. If you plan to publish in AAC, ASM Members get up to 50% off publishing fees. Visit asm.org/joinasm to sign up. Follow Cesar on twitter at https://twitter.com/SuperBugDoc for AAC updates.  Subscribe to the podcast at https://asm.org/eic.

    43 min.
  5. 16. AUG.

    Microbiology in the Headlines: H5N1 in Dairy Cattle, The Plague, Measles, Neosporin and more!

    Join Dr. Ben Pinsky and Dr. Greg Berry as they dissect recent news stories, including the USDA's testing for H5N1 in ground beef and a surprising bubonic plague case in Oregon. They also tackle the resurgence of measles in the U.S., the local reappearance of malaria, and a curious study on Neosporin's potential to prevent viral infections. Overview: H5N1 Influenza Virus: Dr. Ben Pinsky provides an update on recent cases of H5N1 in humans and animals, including concerns about dairy cattle infections and the potential for human transmission. Bubonic Plague: Dr. Greg Berry discusses a recent case in Oregon, its transmission through cats, and the historical context of the plague. Measles: The resurgence of measles in the U.S. is addressed, with Dr. Pinsky noting an increase in cases compared to previous years and emphasizing the importance of vaccination. Malaria: The episode covers recent cases of locally acquired malaria in the U.S. and discusses the history of malaria in America. Neosporin and Viral Infections: The hosts examine a study suggesting Neosporin might prevent viral infections and discuss the implications and practicality of this claim. Guests: Dr. Ben Pinsky Dr. Greg Berry Links: Join ASM for up to 50% off the publication fees when you publish in JCM or any of the ASM journals. This episode of Editors in Conversation is brought to you by the Journal of Clinical Microbiology and hosted by JCM Editor in Chief, Alex McAdam and Dr. Elli Theel. JCM is available at https://jcm.asm.org and on https://twitter.com/JClinMicro. Visit journals.asm.org/journal/jcm to read articles and/or submit a manuscript. Follow JCM on Twitter/𝕏 via @JClinMicro

    29 min.
  6. 28. JUN.

    Turning the Output of the Microbiology Laboratory Into Gold

    The European alchemists of the 12th century sought to find the philosopher’s stone, a substance that would transmute base metals, such as lead, into precious metals, such as silver and gold. Today, we discuss whether data analysis, including machine learning, can transmute base laboratory data into precious clinical tools. We will use antimicrobial susceptibility testing as a case-study for new applications of data analysis. Some of the questions we will address include: How can relatively simple data analyses be used to build upon current methods of verification of antimicrobial susceptibility testing? How do commercial systems analyze individual susceptibility results and can we improve on this analysis using new methods? Finally, what is the long-term potential for leveraging laboratory data and other clinical data to improve and support clinical decision making? And what needs to happen to realize this goal? Guests: Dr. Sanjat Kanjilal (twitter/𝕏) Related article: The modern alchemy of clinical pathology: turning the output of microbiology laboratory operations into gold Links: Join ASM for up to 50% off the publication fees when you publish in JCM or any of the ASM journals. Watch this episode: youtu.be/rWuQ0nSWL1Y This episode of Editors in Conversation is brought to you by the Journal of Clinical Microbiology and hosted by JCM Editor in Chief, Alex McAdam and Dr. Elli Theel. JCM is available at https://jcm.asm.org and on https://twitter.com/JClinMicro. Visit journals.asm.org/journal/jcm to read articles and/or submit a manuscript.

    42 min.

Om

Editors in Conversation is the official podcast of the American Society for Microbiology Journals. Editors in Conversation features discussions between ASM Journals Editors, researchers and clinicians working on the most cutting edge issues in the microbial sciences. Topics include laboratory diagnosis and clinical treatment of infectious diseases, antimicrobial resistance, epidemiology of infections, multidrug-resistant organisms, pharmacology of antimicrobial agents, susceptibility testing, and more. The podcast is directed to microbiologists, infectious diseases clinicians, pharmacists and basic, clinical and translational researchers interested in the microbial sciences. A particular emphasis is on basic, epidemiological and pharmacological aspects of infectious diseases, including antimicrobial resistance and therapeutics.

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