Bills vs. Colts preview: Which running game will reign supreme in Indy?

Matt Parrino and Ryan Talbot break down Sunday's game between the Buffalo Bills and Indianapolis Colts. Both teams are missing key offensive pieces, which means the running game could take center stage. Who holds the advantage? The guys discuss the keys to the game and make their picks.

What is the "SHOUT!" Bills text insiders? Want to join? You can get analysis from Matt and Ryan right to your phone and send texts directly to them both! Text 716-528-6727 or Click here: https://joinsubtext.com/shoutbuffalobills

Sign up for the NYUP Bills newsletter! Don't miss all the Bills coverage. Head over to www.Syracuse.com/newsletters to start getting your Bills stories and the podcast delivered right to your inbox.

SHOUT!" Buffalo Bills football podcast is available on Apple, Spotify, Google, Stitcher, and wherever you listen to podcasts

Follow @MattParrino (https://twitter.com/MattParrino) and @RyanTalbotBills (https://twitter.com/RyanTalbotBills) on Twitter

Find our Bills coverage whenever you like to consume social media

Instagram: https://www.instagram.com/buffalobillsnyup/

Facebook: https://www.facebook.com/buffalobillsnyup

X: https://x.com/billsupdates

Learn more about your ad choices. Visit megaphone.fm/adchoices