The Science of Everything Podcast

James Fodor
  • 5.0 (5)
  • NATURAL SCIENCES
  • EVERY TWO MONTHS
The Science of Everything Podcast

In this podcast I discuss a variety of topics in both the natural and social sciences, exploring the many fascinating insights that the scientific method yields about the world around us.

  1. 30 SEPT

    Episode 148: Control of Gene Expression

    An introduction to the processes by which cells control which genes are expressed. We begin with an overview of why genetic regulation is necessary and the key stages where such regulation occurs, including key concepts such as transcription factors and DNA binding domains. We then discuss prokaryotic gene regulation, focusing on the lac operon in E. coli. We then expand the discussion to cover the various mechanisms of eukaryotic gene regulation, including chromatic remodelling, transcriptional regulation, post-transcriptional regulation, RNA editing, and micro RNAs. Recommended pre-listening is Episodes 34-35: DNA Structure and Function, and Episode 118: Cell Signalling. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything

    1h 9m

  2. 31 AUG

    Episode 147: Genetic Mutation and Repair

    Here we survey of the causes and consequences of genetic mutation, including a discussion of mechanisms of endogenous and induced mutations, rates of mutation, types of single nucleotide mutations, and the phenotypic effects of mutation. We also discuss various mechanisms for detecting and repairing genetic mutations, including base excision repair, DNA mismatch repair, nucleotide excision repair, double strand break repair. We conclude with an examination of large-scale chromosomal changes, including deletions, duplications, inversions, and translocations, unequal crossing over, with a brief look at polypoidy in plants and aneuploidy in humans. Recommended pre-listening is Episodes 34 and 35: DNA Structure and Function, and Episode 44: Cell Division. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything

    1h 14m

  3. 29 JUL

    Episode 146: Mendelian Genetics and Inheritance

    An introduction to classical Mendelian genetics, in which we discuss Mendel's experiments with peas and the laws of heredity that he discovered, including inheritance of one allele from each parent, the law of dominance, and the law of independent segregation. We then consider more complex cases of genetic inheritance, including sex-linked traits, incomplete dominance, codominance, and epistasis. The episode concludes with a discussion of quantitative traits determined by many genes, including how genetic variation is described, how sources of variance are identified using genome wide association studies, and the conceptual issues with defining heredity and separating the effects of genes from those of environment.   If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything Check out out youtube channel!The Science of Everything Podcast - YouTube

    1h 23m

  4. 30 JUN

    Episode 145: Relativity and Black Holes

    Continuing our series on General Relativity, we discuss the derivation of the Schwarzschild metric as a vacuum solution to Einstein's Field Equations, and analyse the physical meaning of this solution, including the properties of the singularity, event horizon, and effects of time dilation and length compression. We then consider how solutions like the Schwarzschild metric yield testable predictions such as gravitational lensing and graviational redshift, which serve as important evidence in support of General Relativity. We conclude with a discussion about some of the more exotic aspects of black holes, including Hawking radiation, the no hair theorem, and the black hole information loss paradox. Recommended pre-listening is Episode 136: Introduction to General Relativity. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything

    1h 26m

  5. 29 MAY

    Episode 144: Anthropogenic Climate Change

    Our climate change series concludes with a discussion of the various lines of evidence indicating that recent warming is the result of human-produced greenhouse gases, including greater warming at night, cooling of the stratosphere, and relative depletion of C14 in the atmosphere. We then consider the various expected impacts of climate change, including increased extreme weather events, acidification of the oceans, changes to crop yields, and affects on various ecosystems. We end with an analysis of the relative costs and benefits of mitigation, and discuss likjely climate projections for the remainder of the 21st century. Recommended pre-listening is Episode 143: Climate Modelling. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything Check out out youtube channel!The Science of Everything Podcast - YouTube

    1h 19m

  6. 28 APR

    Episode 143: Climate Modelling

    An overview of climate models, beginning with a summary of the major types of models, and then a more detailed disussion of hte primitive equations and parameterised feedbacks that characterise the widely used Atmospheric General Circulation Models. We also discuss techniques for model validation and some evidence regarding the accuracy of various climate models. Recommended pre-listening is Episode 142: The Greenhouse Effect. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything Check out out youtube channel!The Science of Everything Podcast - YouTube

    1h 6m

  7. 30 MAR

    Episode 142: The Greenhouse Effect

    A detailed discussion of the greenhouse effect and its impact on Earth's climate. We begin with a discussion of Earth’s energy budget, the various greenhouse gases and their interactions with longwave radiation, and a summary of major sources of greenhouse gas emisions. We then examine the mechanisms of the greenhouse effect in more detail using the idealised greenhouse model and radiative transfer models. We conclude with an analysis of the sensitivity of Earth's climate to changes in greenhouse gas concentrations, and how this interacts with the atmospheric lapse rate. Recommended prelistening is Episode 141: Natural Climate Change. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything

    1h 23m

  8. 29 FEB

    Episode 141: Natural Climate Change

    An overview of the natural mechanisms by which climate changes over time. Beginning with an introduction to the concepts of radiative forcing and climate sensitivity, we then discuss solar forcing, orbital changes, volcanic eruptions, and silicate weathering, covering how each process operates and the effects it has on Earth's climate over varying periods of time. Recommended pre-listening is Episode 140: A History of Earth's Climate. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything

    47 min
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Ratings & Reviews

5
out of 5
5 Ratings

About

In this podcast I discuss a variety of topics in both the natural and social sciences, exploring the many fascinating insights that the scientific method yields about the world around us.

Information

  • Creator
    James Fodor
  • Years Active
    2010 - 2024
  • Episodes
    171
  • Rating
    Clean
  • Copyright
    Copyright © 2010-2022 James Fodor. All rights reserved.
  • Show Website
    The Science of Everything Podcast

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