146 episodes

The health entrepreneurship podcast — focusing on big picture stuff.

Interviews with health/biotech entrepreneurs and leaders having impact at scale. Health stuff a techbro/sis would find interesting. Think health meets the Tim Ferriss Show.

Get in touch: pod@musty.io

Big Picture Medicine Mustafa Sultan, MD

    • Health & Fitness
    • 5.0 • 47 Ratings

The health entrepreneurship podcast — focusing on big picture stuff.

Interviews with health/biotech entrepreneurs and leaders having impact at scale. Health stuff a techbro/sis would find interesting. Think health meets the Tim Ferriss Show.

Get in touch: pod@musty.io

    #129 Jon Ronson on Writing, Hustle and the Psychopath Test

    #129 Jon Ronson on Writing, Hustle and the Psychopath Test

    Jon Ronson is one of the most interesting people alive today — period.

    He’s the author of the Men Who Stare at Goats, So You’ve Been Publicly Shamed and The Psychopath Test — which spent 10 weeks on the New York Times bestseller list.

    His two Ted talks have been watched 20 million times, his books have been brought to life by George Clooney on the big screen, he has written screenplays for Netflix blah blah blah.

    Don’t believe me, listen to a pitch Jon wrote for ‘the Psychopath Test’. If you are not dying to hear what happens next — then, I don’t what to tell you…



    0:00 Jon's pitch for the Psychopath Test

    1:41 Jon's story

    6:00 Strategies Jon used to bypass career gatekeepers

    7:03 Would Jon Ronson be on Substack/podcasting

    12:05 Does Jon Ronson pay attention to analytics? Post mortems

    16:26 Startup philosophy applied to storytelling

    19:08 Writing Advice from Tim Ferriss: Jon's opinion on doing interesting things to write better

    24:59 Does Jon Ronson like being famous?

    28:49 Analysis of 'The Psychopath Test' pitch to Ira Glass

    37:30 Should you make decision based on what would be a good story

    38:48 Jon Ronson's habits for creative success

    • 43 min
    #128 AgeTech: Shopify vs Amazon Model — Birdie CEO, Max Parmentier

    #128 AgeTech: Shopify vs Amazon Model — Birdie CEO, Max Parmentier

    Max Parmentier is the CEO of Birdie, a Series B AgeTech startup who have raised $52M from the likes of Sofina, Omers Ventures and Index Ventures — and captured 10% of the UK market whilst currently scaling into Europe.

    0:00 Intro

    2:37 Shopify vs Amazon model in AgeTech

    7:26 Product pivots: D2C never wins

    11:56 Predictive AI AgeTech

    13:58 I pitch an idea to Max

    19:34 Lessons building Birdie

    24:13 Leaving money on the table for purpose



    Links

    Birdie: https://www.birdie.care/

    Dr Mustafa Sultan: https://www.musty.io/

    • 29 min
    #127 Gentle Disruption Wins in Healthcare — DrDoctor CEO Tom Whicher

    #127 Gentle Disruption Wins in Healthcare — DrDoctor CEO Tom Whicher

    Tom Wicher is CEO of DrDoctor — who have served over 20M patients and just raised £10M in their recent Series A round. But he spent the first 7 years bootstrapping, and diverged from his colleagues: Opting for the slow and steady gentle disruption path. Why?



    0:00 Gentle disruption beats move fast and break things

    3:36 Picking a problem in healthcare

    5:44 Behavioural change theory

    7:52 Stop treating patients like kids

    10:30 Systems-level efficiency vs personalisation

    13:02 Why don't patients show up for their appointments?

    16:02 Overbooking: Learning from airlines

    18:54 Carrot or stick: Motivating health behaviors

    22:35 There's no big conspiracy in healthcare

    26:24 PIFU model of patient booking

    28:14 Sometime it's better not to empower patients

    31:16 Habits/frameworks that have helped Tom succeed



    Links

    DrDoctor: https://www.drdoctor.co.uk/

    Dr Mustafa Sultan: https://www.musty.io/

    • 33 min
    #126 Drug Discovery is Becoming More $$$ — Here's Why, And The Startup Fixing It (Lindus Health)

    #126 Drug Discovery is Becoming More $$$ — Here's Why, And The Startup Fixing It (Lindus Health)

    Drug discovery is becoming more expensive and producing less results than ever before (Eroom's Law)—why?

    One of the ballooning costs are clinical trials. Pharma/biotech often outsource their trials to CROs (contract research organisations).

    But many CROs are incentivised to make trials as bloated and inefficient as possible. That means more money and less results.

    Meri Beckwith is building the anti-CRO: Lindus Health—to solve this problem.



    0:00 Intro

    1:39 The big problem in drug discovery

    4:10 Why do CROs exist?

    7:24 The incentive problem in drug discovery/CROs

    10:57 Pharma are anti-startups

    12:11 How much a clinical trial costs

    15:11 How can you compete with big CROs?

    17:26 Are you going to build your own drug pipeline?

    18:56 Lessons from VC to Founder

    23:42 Brand/PR/Positioning as a biotech startup

    29:03 Billion dollar ideas in bio/health

    31:33 Habits that have helped Meri


    Links

    Lindus Health: https://www.lindushealth.com/

    Meri Beckwith: https://twitter.com/meribeckwith

    Mithi Thaya: https://www.linkedin.com/in/mithi-thaya/

    Dr Mustafa Sultan: https://www.musty.io/

    • 35 min
    #125 The $350M Startup Creating Perfect Memory (Rewind.ai — CEO Dan Siroker)

    #125 The $350M Startup Creating Perfect Memory (Rewind.ai — CEO Dan Siroker)

    Rewind.ai just raised their Series A at a valuation of $350M. Investors include Andreesen Horowitz, Reddit’s Alexis Ohanian and OpenAI’s Sam Altman.

    Rewind sits on your computer and phone, and watches everything you do.

    Then you can ask it questions like: What was that really great Mediterranean recipe I looked at last month? Or I’ve got a call with a client next week, can you summarise every interaction I’ve had with them?

    But here’s where it becomes even weirder, powerful.

    They’ve announced the Rewind Pendant, a small audio recorder that sits on your chest. Rewind will be able to listen in to every conversation you have.

    You can ask it: What birthday present should I get for my partner? Did they drop any hints? Or how many arguments did we have last year?

    Pretty Black Mirror, right?

    Once you get over the ick however, you realise that this is correcting a lagging human function. Just like the cursed amongst us wear glasses; tools like Rewind will repair our broken memories.

    I spoke to Dan Siroker, Rewind’s founder—

    0:00 Intro
    1:54 Lessons from the Obama Campaign
    3:28 How to use science to make your startup succeed
    8:21 Privacy concerns
    17:00 Rewind.ai as a brain-computer interface (BCI)
    20:27 Forgetting is important for human wellbeing
    22:26 Societal impacts of perfect memory
    28:42 Rewind's tech stack
    31:56 The existential risk of startups using GPT
    35:21 D2C is harder than B2B
    37:49 Leadership lessons
    40:31 Perils of being a second time founder
    46:44 Is any publicity good publicity?

    Links
    Rewind: https://www.rewind.ai/
    Dan Siroker: https://twitter.com/dsiroker
    Dr Mustafa Sultan: https://www.musty.io/

    • 49 min
    #124 Wearable Data is Bullsh*t Debate — Maitham Dib (Vital YC21)

    #124 Wearable Data is Bullsh*t Debate — Maitham Dib (Vital YC21)

    People are wearing Apple Watches to their wedding days. Has this whole 'quantified self' movement gone bananas? Is any of this data actually useful?

    I spoke to Maitham Dib about this. He's building Vital (YC21); a startup which makes all wearable/lab data available to other startups/companies.

    0:00 Wearable data is mostly useless
    3:22 The case for wearable data
    6:37 Wearable data is mostly useless
    8:06 Wearable data is useful
    10:16 The big opportunity with wearable/lab data (startups)
    14:15 Naivety as a superpower (Paul Graham)
    15:45 Why building Vital is so hard
    19:31 Pros/cons of an infrastructure play in healthcare
    20:51 How to enterprise sales
    24:09 Lessons from YCombinator
    27:32 The benefits of being an immigrant

    Links
    Vital: https://tryvital.io/
    Dr Mustafa Sultan: https://www.musty.io/

    • 29 min

Customer Reviews

5.0 out of 5
47 Ratings

47 Ratings

Dr Davidson ,

Top quality content

I’ve been listening to this podcast at the very least monthly for the last 2 years and consistently get a lot of value from it. Cracking Podcast that I would highly recommend.

Gramericana ,

My favourite Healthtech podcast

Musty is an incredibly thoughtful, insightful and witty interviewer - I listen to the podcast for his questions more so than the interviewee’s answers!

Kdothadadream ,

Understandable and useful!

Even as a non-medic, I found the content to be understandable and enjoyable. Complex topics are simplified and the guests are always interesting.

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