Irish Haematology Oncology Podcast

Eoin Tabb
  • 5.0 (2)
  • EDUCATION
  • UPDATED WEEKLY
Irish Haematology Oncology Podcast

The Irish Haematology Oncology Podcast is your friendly, jargon-free guide to the world of cancer care. Perfect for doctors, nurses, pharmacists, and anyone interested in simplifying this complex field.

  1. 14/11/2024

    Safe Prescribing in Systemic Anticancer Treatments

    Podcast Description: Navigating the complexities of systemic anticancer therapy (SACT) demands meticulous attention to detail, especially when it comes to prescribing. In this episode of the Irish Haematology Oncology Podcast, join your host Eoin Tabb as he delves into the critical aspects of safe prescribing practices for SACT. We'll explore the reasons why SACT prescribing is considered high-risk, the essential steps involved in the prescribing process for both first and subsequent cycles, and the key components of a comprehensive treatment plan. We'll also discuss the legal requirements and prescribing standards, strategies to mitigate errors, and the unique safety challenges associated with oral anticancer medicines (OAMs). Whether you're at the beginning of your career or seeking a refresher, this episode will equip you with the knowledge and insights to ensure the safe and effective administration of these powerful medications to your patients. Takeaways DPYD testing is crucial for personalized cancer treatment. SACT medications have a narrow therapeutic index. Creating a treatment plan requires meaningful patient conversations. Clear communication among healthcare professionals is essential. Legal standards in prescribing protect patients and prescribers. Ambiguity in prescriptions can lead to serious errors. Pharmacists play a critical role in patient safety. Oral anti-cancer medicines come with unique safety challenges. Regular reassessment of patient fitness for treatment is necessary. Safe prescribing is a shared responsibility among all healthcare providers. Feedback Form IIOP Example CPD for Pharmacists

    23 min

  2. 04/11/2024

    SACT Sequencing

    Podcast Description: Join Eoin Tabb on the Irish Haematology Oncology Podcast as he unravels the critical role of drug sequencing in cancer treatment. Discover how the order of drug administration can impact patient safety, treatment efficacy, and overall well-being. Learn about the dangers of extravasation and how to safely administer vesicant drugs. Explore real-world case studies and gain insights from clinical trials that have shaped our understanding of optimal treatment protocols. This episode is a must-listen for healthcare professionals seeking to enhance their knowledge and skills in oncology care. Show Notes: Drug Sequencing in Cancer Treatment The importance of administering anti-cancer drugs in the correct order The impact of drug sequencing on treatment efficacy, side effects, and drug resistance The role of clinical trials in determining optimal drug sequences Real-world case studies illustrating the impact of drug sequencing Minimizing Infusion-Related Reactions Strategies for reducing the risk of infusion-related reactions The importance of premedication and vigilant monitoring Vesicants and Extravasation The dangers of extravasation and its potential complications Prioritizing the administration of vesicant drugs Using appropriate vascular access devices and meticulous administration techniques The "VIP Access" mnemonic for vesicant management Resources The Morales guide for drug administration sequences The "Chemotherapy Sequencing Chart" Relevant clinical trials and research studies as outlined in episode CPD Document for Pharmacists Feedback Form

    22 min

  3. 12/08/2024

    Chemotherapy Extravasation

    Join us on the Irish Haematology Oncology Podcast as we delve into the critical topic of chemotherapy extravasation. We'll explore what it is, why it happens, and the potential consequences. More importantly, we'll discuss how to prevent it and effectively manage it if it occurs. Whether you're a seasoned healthcare professional or new to the field, this episode offers valuable insights to enhance patient safety and optimize cancer care. Key Points: Understanding Extravasation: The 'leaky pipe' analogy and the varying risks associated with different chemotherapy drugs. Incidence and Risk Factors: Understanding the odds and identifying potential vulnerabilities. Prevention is Key: The importance of meticulous administration techniques and staff training. Early Recognition: The fire alarm analogy and the crucial role of prompt identification. The Extravasation Kit: A lifeline in emergencies and the importance of preparedness. Managing Extravasation: The first response and the tailored approach to treatment. The Unique Challenge of CVAD Extravasation: The 'basement leak' analogy and the complexities involved. The Road to Recovery: Follow-up care, patient education, and the importance of documentation. Resources: ESMO-EONS Clinical Practice Guidelines on extravasation management Feedback Form: https://forms.gle/DzC4ye9edfV4rMZF8 CPD IIOP Example: https://docs.google.com/document/d/1RIJK6JPQDKRU-ZUTOCBlvA_I3_hS0Yd9thPibZpN0QA/edit?usp=sharing

    30 min

  4. 29/07/2024

    SACT Specific Ancillary Medication Considerations (Part 2)

    Join host Eoin Tabb on the Irish Haematology Oncology Podcast as he delves into the critical role of ancillary medications in chemotherapy. This episode focuses on essential supportive care drugs like vitamins, steroids, and hydration protocols, highlighting their mechanisms, administration, and importance in mitigating side effects and optimizing treatment outcomes. Learn about: Hydration in cisplatin and methotrexate regimens Folinic acid rescue in high-dose methotrexate treatment Mesna prophylaxis for hemorrhagic cystitis in cyclophosphamide and ifosfamide regimens Practical tips for managing common chemotherapy side effects 2. Podcast Show Notes: Hydration Protocols: The importance of maintaining adequate fluid intake before, during, and after chemotherapy to protect kidney function and minimize toxicity. Cisplatin and Nephrotoxicity: The risks of kidney damage associated with cisplatin and the specific hydration strategies used to mitigate these risks. Methotrexate and Folinic Acid: The combined use of hydration, alkalinization, and folinic acid rescue to prevent kidney damage and protect healthy cells from methotrexate's effects. Hemorrhagic Cystitis: The role of mesna in preventing bladder inflammation and bleeding caused by cyclophosphamide and ifosfamide. Practical Tips: Additional strategies for managing common side effects like nausea, vomiting, diarrhea, and fatigue. Feedback Form: https://forms.gle/ctCHDcc7d4W4NfB18 IIOP Education Document (same as last episode): https://docs.google.com/document/d/1d1KEtJ6yrZ_fMGMLgTFgQ762rX0-y5vbb4ikDsr_U6s/edit?usp=sharing

    16 min

  5. 22/07/2024

    SACT Specific Ancillary Drug Considerations (Part 1)

    Summary This episode of the Irish Hematology Oncology podcast explores the importance of ancillary medications in chemotherapy regimens. The host discusses specific medications used to address the side effects and risks of chemotherapy drugs, including Pemetrexed with vitamin B12 and folic acid, Docetaxel with corticosteroids, Irinotecan with atropine, and 5-FU with leucovorin. Each medication is explained in detail, highlighting its role in managing side effects and enhancing the effectiveness of chemotherapy. Takeaways Ancillary medications play a crucial role in managing side effects and enhancing the effectiveness of chemotherapy drugs. Pemetrexed can deplete the body's stores of vitamin B12 and folic acid, so supplementation is necessary to prevent deficiencies and reduce the risk of severe side effects. Corticosteroids like dexamethasone are prescribed alongside Docetaxel to manage fluid retention. Atropine is used as an antidote to counteract the cholinergic reaction caused by Irinotecan. Leucovorin is used to protect healthy cells and enhance the action of 5-FU in chemotherapy. Consult with healthcare professionals for personalized guidance and stay updated on the latest recommendations in cancer care. IIOP CPD Example: https://docs.google.com/document/d/1d1KEtJ6yrZ_fMGMLgTFgQ762rX0-y5vbb4ikDsr_U6s/edit?usp=sharing Feedback Form: https://forms.gle/ortbvq6Ld19zSCDG7

    14 min
  6. Common Skin Reactions in Cancer Treatments

    08/07/2024

    Common Skin Reactions in Cancer Treatments

    Join Eoin Tabb on the Irish Haematology Oncology Podcast as he delves into the common skin reactions caused by cancer treatments. This episode is a must-listen for healthcare professionals seeking to enhance patient care by understanding, preventing, and managing these often-overlooked side effects. From acneiform rash to hand-foot syndrome, hair loss, drug-induced pruritus, paronychia, and onycholysis, Eoin breaks down the incidence, diagnosis, pathology, and treatment options for each condition. Gain valuable insights and practical tips to improve your patients' quality of life during their cancer journey. Tune in and empower yourself to make a real difference in your patients' well-being. In this episode of the Irish Haematology Oncology Podcast, host Eoin Tabb discusses common skin reactions caused by cancer treatments. He covers the following topics: Acneiform Rash: Incidence, diagnosis, pathology, prevention, and treatment options, including topical steroids, oral antibiotics, and oral steroids. Hand-Foot Syndrome (HFS): Incidence, diagnosis, pathology, prevention strategies (moisturizing, avoiding friction, protecting from heat), and treatment options (topical corticosteroids, pain relievers, keratolytics, cooling). Chemotherapy-Induced Alopecia (CIA) and Endocrine Therapy-Induced Alopecia (EIA): Incidence, diagnosis, pathology, prevention (scalp cooling for CIA), and supportive care options (wigs, hairpieces, nutritional supplements). Drug-Induced Pruritus: Incidence, diagnosis, severity rating scales, management options for mild, moderate, and severe cases (moisturizers, anti-itch creams, topical corticosteroids, oral antihistamines, gabapentin, pregabalin, oral corticosteroids). Paronychia: Incidence, diagnosis, pathology, prevention (nail care, hygiene, moisturizing), and treatment options (topical antiseptics, corticosteroids, antibiotics, nail removal). Taxane-Induced Onycholysis: Incidence, diagnosis, pathology, prevention (moisturizing, nail protection, cooling), and treatment options (nail care, antibiotics, nail removal). Eoin emphasizes the importance of early intervention, open communication with patients, and tailoring treatment plans to individual needs. He also provides resources for further learning and encourages listeners to stay informed about the latest research and treatment options. References: Lacouture, M. E., Sibaud, V., Gerber, P. A., van den Hurk, C., Fernández-Peñas, P., Santini, D., ... & Jordan, K. (2021). Prevention and management of dermatological toxicities related to anticancer agents: ESMO Clinical Practice Guidelines. Annals of Oncology, 32(2), 157-170. Feedback Form: ⁠https://forms.gle/AEcFAHCnykCNkKDJ9 CPD IIOP Example Link: https://docs.google.com/document/d/1l6UeJ1hMIQaeVChTCq3_l5A_f9MPms_DaY4EZ-WNBv4/edit?usp=sharing

    24 min
  7. Immune Related Adverse Events

    01/07/2024

    Immune Related Adverse Events

    In this episode, Eoin Tabb, a clinical cancer services pharmacist, unravels the complexities of immune checkpoint inhibitors (ICIs), the superheroes of cancer therapy. We'll explore how ICIs unleash the immune system to fight cancer, the potential side effects known as immune-related adverse events, and how healthcare professionals can effectively manage them. From common skin reactions and endocrine disruptions to rare neurological and cardiac complications, we'll cover it all. Tune in to understand how ICIs are revolutionizing cancer treatment while being prepared for their unique challenges Introduction: Immune checkpoint inhibitors (ICIs) as revolutionary cancer treatments. What are ICIs? How ICIs work by removing cancer's "invisibility cloak" to the immune system. Immune-Related Adverse Events (irAEs): Explanation of irAEs as a side effect of overactive immune response. Common irAEs: Other irAEs: Neurological, cardiovascular, renal, hematologic, ocular. Overlapping Syndromes: Myocarditis-myositis overlap, myasthenia gravis. Management of irAEs: Long-Term Management: Ongoing monitoring for late-onset or recurrent irAEs. Emerging Therapies: Targeted therapies, personalized medicine. Important Disclaimer: Consult healthcare providers for personalized guidance. CPD IIOP Example: https://docs.google.com/document/d/1lI2B0iiLxYAHkvkWo8AjHvw-fjnCwc4DcioSiVF4Ptw/edit?usp=sharing Feedback Form: https://forms.gle/AEcFAHCnykCNkKDJ9 References: ESMO Guidelines: https://www.annalsofoncology.org/article/S0923-7534(22)04187-4/fulltext

    24 min

  8. 24/06/2024

    Hepatic Impairment in Cancer Care

    Join Eoin Tabb on the Irish Haematology Oncology Podcast for a deep dive into hepatic impairment in cancer patients. We'll break down the vital functions of your liver, how we measure its health, and why this is crucial when planning chemotherapy. Whether you're a new healthcare professional or a seasoned expert, this episode is packed with insights on how to navigate the complexities of chemo dosing when the liver isn't functioning at its best. Tune in to learn how to keep your patients safe and optimize their treatment outcomes! Podcast Show Notes: The Liver: Your Body's Metabolic Powerhouse and Detoxification Center The liver's multiple roles: detoxification, nutrient processing, production of essential substances The liver's role in medication metabolism The impact of hepatic impairment on chemotherapy: increased drug levels, decreased drug activation, altered blood flow, and protein binding issues When the Liver Hits a Snag: Types and Causes of Hepatic Impairment Degrees of hepatic impairment: mild, moderate, severe Common causes: chronic liver diseases (cirrhosis, hepatitis, NAFLD), medications (chemotherapy, other drugs), alcohol abuse, other causes Types of liver damage: hepatocellular, cholestatic, mixed Measuring Liver Health: The Tools and the Challenges Child-Pugh score: assessing liver function based on bilirubin, albumin, INR, ascites, and encephalopathy NCI Organ Dysfunction Criteria: focusing on bilirubin and liver enzymes (ALT, AST) The importance of context and clinical judgment in interpreting test results The Domino Effect of Hepatic Impairment on Chemo: Increased risk of toxicity Issues with prodrugs Impact on biliary excretion, blood flow, and protein binding The importance of individualizing treatment based on cancer type, treatment goals, and patient resilience The challenges of dose adjustments Sign up for Irish Haematology Oncology Podcast mailing list to keep in touch: http://eepurl.com/iPyGn-/ CPD IIOP Example: https://docs.google.com/document/d/1qDbcXuLKcPCvufJCfAg0tjsaH5uuUqaaQhjHC7xGmJU/edit?usp=sharing Feedback Form: https://forms.gle/EqQU4tVr84STHftS9

    24 min
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2 Ratings

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The Irish Haematology Oncology Podcast is your friendly, jargon-free guide to the world of cancer care. Perfect for doctors, nurses, pharmacists, and anyone interested in simplifying this complex field.

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