8 episodes

On this podcast, Christina Applegate and Jamie-Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

MeSsy with Christina Applegate & Jamie-Lynn Sigler Wishbone Production

    • Society & Culture
    • 4.7 • 26 Ratings

On this podcast, Christina Applegate and Jamie-Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

    Jimmy Kimmel

    Jimmy Kimmel

    This week, Christina and Jamie are joined by their friend, Jimmy Kimmel. They discuss finding humor in tough situations, the things he still wants to accomplish, speaking from your heart, mean tweets, and much more.

    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This show is sponsored by:
    Maybelline - If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more
    Lolavie - Get 15% off LolaVie with code MESSY at https://www.lolavie.com/MESSY! #lolaviepod
    ZocDoc - Go to Zocdoc.com/MESSY and download the Zocdoc app for FREE. Then find and book a top-rated doctor today

    • 53 min
    Can I Be Honest?

    Can I Be Honest?

    This week, Christina and Jamie discuss feeling obligated to be strong, the importance of being there for each other, wearing diapers, and much more. They also answer some listener questions.
    Parts of this episode were recorded in 2023.

    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This episode is sponsored by:
    Maybelline - If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more.
    Cionic - MeSsy listeners can get $50 off by entering the code MESSY during checkout visit cionic.com

    Jamie-Lynn Sigler is a paid spokesperson for Novartis. This podcast is independent from Jamie-Lynn Sigler’s collaboration with Novartis.

    • 48 min
    Martin Short

    Martin Short

    This week, Christina and Jamie are joined by Christina's friend, the one and only Martin Short. They reminisce about working together, share funny stories, discuss colonoscopy parties, and much more.

    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch
    This episode is sponsored by/brought to you by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self.

    • 1 hr 7 min
    It’s Okay to Be the Caboose

    It’s Okay to Be the Caboose

    This week, Christina and Jamie discuss traveling, the feeling of being a burden, the importance of listening to your body, and more. They also answer some listener questions.
    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch
    This episode is sponsored by/brought to you by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self.
    *Parts of this episode were recorded in 2023.

    Jamie-Lynn Sigler is a paid spokesperson for Novartis. This podcast is independent from Jamie-Lynn Sigler’s collaboration with Novartis.
    If you'd like to send us a question or comment, fill out the form on messythepodcast.com

    • 49 min
    The Power of Now

    The Power of Now

    This week, Christina and Jamie discuss the importance of being honest about how they're feeling, their love of New York, how to be less hard on themselves, and more. They also answer some listener questions.

    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    *Parts of this episode were recorded in 2023.

    • 57 min
    Edie Falco

    Edie Falco

    This week, Christina and Jamie are joined by Edie Falco, who starred on "The Sopranos" with Jamie. They share their perceptions of each other while working on the show, and discuss parenting, cancer, the importance of being vulnerable, and more.

    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    • 50 min

Customer Reviews

4.7 out of 5
26 Ratings

26 Ratings

Viv030974 ,

Finally, real insights into MS

Thanks for making a heavy subject light and real, and making it seem like no big deal!

Vivienne

yournightmxre__ ,

Finally…

There are those on the fringe actors who do their own thing and seem to be a bit more real than others in the Hollywood sphere. I feel like Christina falls into that category and why I have followed her throughout the years since Married with Children.
I also used to watch the Sopranos religiously when it first came out and had no idea that over 20 years later I’d be here listening to Christina and Meadow, I mean Jess waxing lyrical about MS.

I also didn’t think I would also be dealing with my own autoimmune issues (that no one quite understands as it’s invisible to others) in the future. So, I’m really happy that both Christina and Jess decided to do this and throw some light onto something as life changing as MS in such detail.

It’s refreshing to hear similar stories with such depth, humour and off the cuff no holds barred conversation which include and delve into the intricacies of your own life. It’s appreciated.

drjaneharry ,

Love this!

Love this! So glad you’re doing it, will do so much to support folks with MS and raise wider awareness. I’m just going into the sixth year of my MS life sentence, looking forward to joining you for more honest and funny chats.

Top Podcasts In Society & Culture

Life with Nat
Keep It Light Media
Miss Me?
BBC Sounds
The Louis Theroux Podcast
Spotify Studios
How To Fail With Elizabeth Day
Elizabeth Day and Sony Music Entertainment
Uncanny
BBC Radio 4
Desert Island Discs
BBC Radio 4

You Might Also Like

Sibling Revelry with Kate Hudson and Oliver Hudson
iHeartPodcasts
Let's Talk Off Camera with Kelly Ripa
Kelly Ripa
Literally! With Rob Lowe
Stitcher & Team Coco, Rob Lowe
misSPELLING
iHeartPodcasts
Dinner’s on Me with Jesse Tyler Ferguson
Sony Music Entertainment
SmartLess
Jason Bateman, Sean Hayes, Will Arnett