Onc Now: Episode 11: Innovations in Gynaecological Oncology

In this episode of the Onc Now Podcast, host Jonathan Sackier is joined by Donal Brennan, a leader in gynaecological oncology and Principal Investigator at Systems Biology Ireland. Together, they discuss advances in ovarian cancer surgery, including cytoreductive techniques and hyperthermic intraperitoneal chemotherapy (HIPEC), as well as the impact of obesity on cancer development and treatment strategies. 

Brennan also shares insights on platinum resistance in ovarian cancer, the FeMMe trial exploring weight loss as a treatment for endometrial cancer, and his innovative approaches in surgical oncology. 

This episode is essential listening for anyone interested in the future of cancer treatment, innovation in surgery, and patient-centred care. 

Timestamps: 

(00:00) - Introduction 

(01:51) - Music debates in the surgical theatre 

(03:42) - Evolution of surgical techniques in ovarian cancer 

(06:32) - The importance of early diagnosis 

(08:18) - State-of-the-art on HIPEC in gynaecological oncology 

(11:36) - Obesity’s impact on cancer diagnosis and treatment 

(19:06) - The FeMMe trial: weight loss as a treatment for endometrial cancer 

(21:47) - Platinum resistance in ovarian cancer and future therapies 

(28:14) - Innovation in gynaecological surgery and medical technology 

(29:53) - The COMFORT trial: mental health and cancer treatment 

(33:24) - Biggest challenges and opportunities in gynaecological oncology research 

(37:42) - Three wishes for the future of cancer treatment